Results 231 to 240 of about 267,118 (262)

Ocular Manifestations Associated with Hematologic Malignancies: Mechanisms, Diagnosis, and Management. [PDF]

Med Sci (Basel)
Xiao Y, Zou Y, Yang M, Zhang J, Ohno-Matsui K, Kamoi K.   +5 more
europepmc   +1 more source

Melatonin Mitigates Doxorubicin‐Induced Cardiotoxicity by Targeting the USP18/PKM2 Axis Without Compromising Antitumor Efficacy

Advanced Science, EarlyView.
Melatonin engages MT1/MT2 receptors to suppress STAT1‐driven USP18 upregulation, thereby redirecting PKM2 ubiquitination from K33‐linked autophagic degradation toward K27‐linked nuclear translocation. This prevents PKM2‐mediated proinflammatory gene expression in the heart, alleviating doxorubicin‐induced cardiotoxicity without compromising antitumor ...
Zhenyu Feng, Yijin Yang, Jie Bai, Pengqi Sun, Xuyang Sun, Jinshu Shang, Yang Liu, Zhen Ning, Ningning Zhang, Yun‐long Xia, Yunpeng Xie   +10 more
wiley   +1 more source

Antimicrobial Resistance Patterns in Infections Among Patients With Hematologic Malignancies: A Systematic Review. [PDF]

Cureus
Kaur Soni T, Kshatri AHS, Femy A, Verma B, Verma P, Dutta S, Bodanam S, Johnson LS, R K, Devarapalli J, V P A, Ns D, Shrivastava S, Keshari Samal S.   +13 more
europepmc   +1 more source

pH‐Responsive Nanoplatform‐Mediated Lipid Hijacking and Metabolic Collapse for Synergistic Starvation‐Immunotherapy

Advanced Science, EarlyView.
A pH‐responsive ZIF‐8/2‐DG@Cu‐TA nanoplatform orchestrates multifaceted metabolic disruption for synergistic starvation‐immunotherapy. Acid‐triggered 2‐DG release blocks glycolysis, while Zn2+ overload induces mitochondrial dysfunction. Concurrently, Cx43‐mediated gap junctions redirect lipid droplets from tumor cells to cancer‐associated fibroblasts ...
Xianlong Zong, Haochen Yao, Danyang Shen, Furu Gong, Zixuan Wang, Haoyang Qin, Yang Yang, Ruirui Qiao, Yongjuan Li, Rui Li   +9 more
wiley   +1 more source

Central Nervous System Toxoplasmosis Beyond HIV in Patients with Hematologic Malignancies: A Contemporary Narrative Review and Illustrative Case Synthesis. [PDF]

Int J Mol Sci
Łanocha A, Pawelec-Pęciak O, Kot K, Machaliński B, Kosik-Bogacka DI, Łanocha-Arendarczyk N.   +5 more
europepmc   +1 more source

MicroRNA‐941 Acts as a Novel Prognostic Predictor and Oncogenic Driver in Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
Upregulation of miR‐941 was a promising diagnostic and prognostic biomarker for CRC patients. Inhibition of miR‐941 significantly suppressed CRC cellular events and triggered ferroptosis. The oncogenic functions of miR‐941 were mediated through targeting TRPS1.
Hong Li, Yang Liu, Hua Chen, Jialin Li, Xinchun Li, Yanmin Chen   +5 more
wiley   +1 more source

Leveraging Dietary Interventions to Benefit Patients with Hematologic Malignancies and Clonal Hematopoiesis. [PDF]

Nutrients
Brzechffa C, Fleischman AG.
europepmc   +1 more source

The silent pharmacist: Harnessing the gut microbiome to improve therapy in hematologic malignancies. [PDF]

Transl Oncol
El-Sehrawy AAMA, Soleimani Samarkhazan H.   +1 more
europepmc   +1 more source

Population Pharmacokinetic Modeling and Exposure-Response Analyses of Nemtabrutinib in Patients With Hematologic Malignancies. [PDF]

CPT Pharmacometrics Syst Pharmacol
Kemal CC, Zweers TJ, Krekels EHJ, Chatterjee MS.   +3 more
europepmc   +1 more source

Heteroplasmic variants of mitochondrial genome in tumor and normal samples from patients with hematologic malignancies. [PDF]

Leukemia
Davini A, Iannelli F, Rossi A, Zanetti S, Salemi D, Mazzara S, Mangione M, Talarico G, Bertolini F, Tarella C, Chiarle R, Derenzini E.   +11 more
europepmc   +1 more source