Results 151 to 160 of about 84,691 (282)

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

Advanced Science, EarlyView.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang, Junteng Qiu, Yunfeng Lu, Yahui Song, Xinyu Zhou, Tianshun Duan, Xuanqi Peng, Caixia Yin, Cheng Gao, Ruibing Wang   +9 more
wiley   +1 more source

Safety and Feasibility of Transcatheter Aortic Valve Replacement in Patients With Hematologic Neoplasms. [PDF]

JACC Case Rep
Prinz NW, Thomas J, Mathew MA, Mehta JJ, Mohanty BD.   +4 more
europepmc   +1 more source

Beating Hematological Neoplasms

Journal of Nihon University Medical Association, 2023
openaire   +1 more source

Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang, Ning Lu, Zhuo Yan, Luyi Ye, Luyao Bai, Shanshan Yuan, Yuting Zhu, Yiru Xiong, Yongheng Bai, Yaping Chen, Junjie Deng   +10 more
wiley   +1 more source

Performance and clinical utility of Spanish germ line genetic testing criteria for hematologic neoplasms predisposition. [PDF]

Blood Adv
Torres-Esquius S, Ramil-López G, Gabarrós-Subirà M, Diaz-Beya M, Rivero E, Garcia-Maño L, López-Cadenas F, Fernandez-Rodriguez C, Guijarro F, Acha P, Novoa-Jauregui S, Palomo L, Tuset E, Pratcorona M, Valcarcel D, Bosch F, Jerez A, Montoro MJ.   +17 more
europepmc   +1 more source

Topotecan in second-line therapy of SCLC: Impact on survival? [PDF]

, 2000
Kleinschmidt, R., Hruska, D., Mezger, J., Pawel, J. von, Saal, J. G., Gatzemeier, U., Steppling, H., Huber, Rudolf M., Gosse, H., Steppert, C.   +9 more
core   +1 more source

Self‐Accelerating Bimetallic Peroxide Nanozymes for Cascade‐Amplified Pyroptosis‐Immunotherapy

Advanced Science, EarlyView.
Acidic tumor microenvironment‐responsive CuZnONPs enable triple‐combination therapy via self‐supplying H2O2, cascade nanozyme activities for ROS burst, and Zn2+‐activated pyroptosis, synergizing catalytic therapy with immunotherapy to convert cold tumors into hot ones.
Xuanyi Lu, Liang Li, Siyu Pan, Yuehan Jian, Yuhan Chen, Wenjie Yang, Guang Song, Xueyang Fang, Ping'an Ma, Lijun Jiang   +9 more
wiley   +1 more source

Management of elderly patients with hematological neoplasms

Annals of Oncology, 2007
O, Mora, E, Zucca
openaire   +2 more sources

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

Advanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu, Xin Chen, Qingyang Zhao, Weikang Tan, Lingrui Zhu, Kin Liao, Vincent Chan, Nicolae Goga, Winfred O. Larkotey, Yang Li, Yinghui Shi, Wenya Shu, Lin Wang, Weiqing Wang, Tian Jian Lu, Yulong Han   +15 more
wiley   +1 more source