Application of cell-derived exosomes in the hematological malignancies therapy
Frontiers in Pharmacology, 2023 Exosomes are small membrane vesicles of endocytic origin that are produced by both tumor and normal cells and can be found in physiological fluids like plasma and cell culture supernatants.
Kazem Ghaffari +7 more
doaj +1 more source
Effect of Combined Oral Ferrotherapy with L-carnitine on Exercise Tolerance of Patients with Chronic Heart Failure with Reduced Ejection Fraction of Left Ventricle with Concomitant Iron Deficiency Anemia [PDF]
, 2019 According to numerous studies, a high prevalence of iron deficiency (ID) with anaemic syndrome and its association with mortality during chronic heart failure (CHF) have been revealed.
Ivanov, V. (Valerii) +1 more
core +3 more sources
Modelling hematopoiesis mediated by growth factors with applications to periodic hematological diseases [PDF]
, 2006 Hematopoiesis is a complex biological process that leads to the production and regulation of blood cells. It is based upon differentiation of stem cells under the action of growth factors.
Adimy, Mostafa +2 more
core +5 more sources
Онкогематология, 2014 The additional molecular and chromosomal abnormalities (ACA) in Phositive cells usually considered as a genetic marker of chronic myeloid leukemia (CML) progression.
O. Yu. Vinogradova +22 more
doaj +3 more sources
Increased mortality in hematological malignancy patients with acute respiratory failure from undetermined etiology : a Groupe de Recherche en Réanimation Respiratoire en Onco-Hématologique (Grrr-OH) study [PDF]
, 2016 Background: Acute respiratory failure (ARF) is the most frequent complication in patients with hematological malignancies and is associated with high morbidity and mortality.
Azoulay, Elie +19 more
core +2 more sources
Онкогематология, 2014 Literature data of idiopathic myelofibrosis are presented: classification, diagnostic criteria, morphological and molecular features. Particular attention is given to therapy of various clinical forms of primary myelofibrosis.
L. M. Meshcheryakova +4 more
doaj +3 more sources
Toxicity Analysis in the ADEBAR Trial: Sequential Anthracycline-Taxane Therapy Compared with FEC120 for the Adjuvant Treatment of High-Risk Breast Cancer [PDF]
, 2012 Background: Data from meta-analyses have shown taxane-containing therapies to be superior to anthracycline-based treatments for high-risk breast cancer. Patients and Methods: The ADEBAR trial was a multicenter phase Ill trial in which patients with lymph
Aivazova-Fuchs, Viktoria +16 more
core +1 more source
Predictive value of hematological and phenotypical parameters on postchemotherapy leukocyte recovery [PDF]
, 2009 Background: Grade IV chemotherapy toxicity is defined as absolute neutrophil count <500/μL. The nadir is considered as the lowest neutrophil number following chemotherapy, and generally is not expected before the 7th day from the start of chemotherapy.
Abbasciano V +15 more
core +1 more source
Complete blood count: absolute or relative values? [PDF]
, 2016 Background: For many years, relative values based on 100 quantified cells have been used to assess blood counts in the field of hematology. However, modern blood counting machines have recently made it possible to determine absolute counts.
Arneth, Borros
core +1 more source
High efficacy and low toxicity of weekly docetaxel given as first-line treatment for metastatic breast cancer [PDF]
, 2005 Background: Docetaxel is one of the most effective antitumor agents currently available for the treatment of metastatic breast cancer (MBC). This phase II multicenter study prospectively analyzed the efficacy and toxicity of docetaxel given on a weekly ...
Ajani JA +26 more
core +1 more source