Results 271 to 280 of about 474,063 (338)

COVID-19-Related Hematological Abnormalities Among Adults; A Cross-Sectional Study in a Resource-Limited Setting. [PDF]

Immun Inflamm Dis
Nkansah C, Osei-Boakye F, Appiah SK.
europepmc   +1 more source

P-635. Clinical Impact and Comparative Outcomes of hMPV and RSV Infections in Hematological Malignancy Patients: A Multinational Cohort Study

Jon Salmanton‐García, Francesco Marchesi, Oliver A Cornely, L Pagano   +3 more
openalex   +1 more source

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

Correction: Genetic polymorphisms in cGAS-STING-mediated type I interferon innate immune signaling pathway are associated with DLBCL. [PDF]

Front Immunol
Zhou Q, Jia R, Chen J, Tan Y, Ma Y, Luan M, Sheng X, Han X, Li S, Lu F, Ji C, Wang D, Ye J.   +12 more
europepmc   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Patient Blood Management in Hematology: Focusing on Platelet Transfusion. [PDF]

J Clin Med
Solves P, Córcoles M, Soriano M, Lamas B, Martínez-Campuzano D, Asensi P, Gómez-Seguí I, de la Rubia J.   +7 more
europepmc   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Diversity Analysis of Fecal Microbiota in Goats Driven by White Blood Cell Count. [PDF]

Microorganisms
Zeng M, Zhou H, Wu Q, Wang K, Liu H, Yang Y, Peng W, Chen A, Deng X, Ji C, Zhang X, Han J.   +11 more
europepmc   +1 more source

Hematological ratios, immune-related adverse events and mortality in patients treated with immune checkpoint inhibitors. [PDF]

PLoS One
Lekkerkerker S, Kaasjager KAH, Haitjema S, Hulsbergen-Veelken C, Herbschleb KH, Verhaar MC, Khairoun M, Ocak G.   +7 more
europepmc   +1 more source