Results 111 to 120 of about 575,997 (353)
Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis
ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin+10 more
wiley +1 more source
Objective Systemic sclerosis (SSc) is a rare autoimmune disease characterized by tissue fibrosis, vasculopathy, and immune dysregulation. Our objectives were to quantify the overall and site‐specific cancer risks in patients with SSc compared to the general population, examine temporal trends in cancer incidence following SSc diagnosis, and explore ...
Jihyun Na+4 more
wiley +1 more source
Background/Objectives: Thrombotic thrombocytopenic purpura (TTP) is a microangiopathic hemolytic anemia exhibiting 90% mortality without prompt treatment.
Brenna S. Kincaid+5 more
doaj +1 more source
Objective Lupus low disease activity state (LLDAS) is a validated treatment target in systemic lupus erythematosus (SLE) but limited studies have explored the role of LLDAS in lupus nephritis (LN). This study aims to investigate the frequency and predictors of LLDAS attainment, and its benefit on LN relapse and renal function preservation in patients ...
Chak Kwan Cheung+6 more
wiley +1 more source
Relationship between HMGB1 and PAI-1 after allogeneic hematopoietic stem cell transplantation
Shosaku Nomura,1 Yoshinobu Maeda,2 Kazuyoshi Ishii,1 Yuta Katayama,3 Hideo Yagi,4 Naoto Fujishima,5 Shuichi Ota,6 Masato Moriyama,7 Takayuki Ikezoe,8 Yasuhiko Miyazaki,9 Kunio Hayashi,10 Shinya Fujita,1 Atsushi Satake,1 Tomoki Ito,1 Taiichi Kyo,3 Mitsune
Nomura S+15 more
doaj
Objective This study aimed to determine if program format (in‐person, virtual, hybrid) results in differences in three‐month outcomes of pain, function, quality of life, self‐efficacy and chair stands in a hip/knee osteoarthritis management program. Methods A secondary analysis of the GLA:DTM Canada database was completed.
Jill Van Damme+7 more
wiley +1 more source
Introduction: Hematology section provides valuable information for diagnosis and treatment of patients to improve the health of them. In this regard Hematology Information System led to deliver produced information accurately and timely.
Farkhondeh Asadi+2 more
doaj
Objectives This study aimed to identify the frequency and determinants of Lupus Low Disease Activity State (LLDAS) and Definition of Remission in SLE (DORIS‐remission) attainment in systemic lupus erythematosus (SLE) patients with clinically active disease, and the frequency and determinants of flare and damage accrual after target attainment.
Yanjie Hao+39 more
wiley +1 more source
This research has the objectives to determine LC50 96 hours value and observation toward hematology, gills and kidney histology of goldfish (Cyprinus carpio) exposed to organophosphate pesticide with Poksim active compound (trade brand FOKKER 500 EC ...
Dewi Nur Setyorini+2 more
doaj