Results 141 to 150 of about 90,270 (303)

Impact of Germline DNA Repair Mutations on Clonal Hematopoiesis and Myeloid Neoplasm Development. [PDF]

Curr Hematol Malig Rep
Fedorov K, Luo LY, Bick AG, Savona MR.
europepmc   +1 more source

Integrative analysis of copper dysregulation and cuproptosis in postnatal hematopoiesis

Liyun Chen, Qian Wu, Chaohui Lin, Zijun Song, Yunxing Su, Chaodong Ge, Xue Wang, Hongbing Luo, Rong Wang, Yanfang Wang, Junxia Min, Fudi Wang   +11 more
openalex   +1 more source

Extramedullary hematopoiesis in ovary: a rare presentation of CML

, 2019
Akriti Agarwal, Asha Gokhale
openalex   +2 more sources

Type I Interferon Pathway Activation Disrupts Monocyte Maturation and Enhances Immune Evasion in Multiple Myeloma

Advanced Science, EarlyView.
This study shows that monocytes in multiple myeloma display an excessive interferon response, leading to transcriptional reprogramming and altered differentiation. Using single‐cell sequencing, coculture experiments, and patient samples before and after therapy, the authors demonstrate that induction treatment reduces this interferon response ...
Jian Cui, Jingwei Wang, Xiaoyun Li, Lina Wang, Xuehan Mao, Rui Lyv, Wenqiang Yan, Jingyu Xu, Jieqiong Zhou, Chenxing Du, Shuhui Deng, Mu Hao, Yan Xu, Shuhua Yi, Dehui Zou, Tao Cheng, Xin Gao, Lugui Qiu, Gang An   +18 more
wiley   +1 more source

Real-ambient PM_2.5 exposure disrupts hematopoietic homeostasis via HIF-1α-driven myeloid skewing and promotes organ inflammation. [PDF]

Part Fibre Toxicol
Yu H, Chen Y, Wang Y, Li M, Tang G, Zhang R, Qu G, Jin X, Zheng Y, Jiang G.   +9 more
europepmc   +1 more source

The Disordered Region of ASXL1 Acts as an Auto‐Regulator Through Condensation

Advanced Science, EarlyView.
ASXL1's long IDR encodes an electrostatic “basic platform + acidic brake” that autoregulates condensation. Truncation at a clinical hotspot lifts this brake, forming condensates that retarget BRD2, remodel local chromatin accessibility, and impair neutrophil maturation.
Xiao Fang, Qiwei Li, Wenqing Zhang
wiley   +1 more source

Lexicon for Clonal Hematopoiesis in Liquid Biopsy. [PDF]

Clin Transl Sci
Tell R, Zehir A, Anfora AT, Basu G, Beidelschies M, Compton C, Cristiano S, Godsey JH, Hu J, Johann DJ, Juntilla M, Kansal R, Lo C, Lopez Ramos D, Mahaganapathy V, Merriam D, Rolfo C, Russell H, Singh U, Stetson D, You M, Leiman LC.   +21 more
europepmc   +1 more source

Regulation of Hematopoiesis [PDF]

, 1990
David G. Nathan
openalex   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Clonal hematopoiesis and subsequent venous thromboembolism among survivors of autologous transplantation for lymphoma. [PDF]

J Natl Cancer Inst
Gangaraju R, Chen Y, Hageman L, Bosworth A, Ross E, Francisco L, Singh P, Richard MA, Yan C, Kalra R, Cheng C, Armenian SH, Forman SJ, Bhatia R, Bhatia S.   +14 more
europepmc   +1 more source