Results 141 to 150 of about 109,190 (303)

Stochastic Modeling of Early Hematopoiesis

open access: yes, 2007
Hematopoiesis is the body's way of making the cellular constituents of blood. Oxygen transport, response to infections, and control of bleeding are among the functions of different mature blood cells.
Renato Assunção   +5 more
core  

Patterns of Wnt/Fzd/LRP gene expression during embryonic hematopoiesis

open access: yes, 2009
Wnt signaling plays several roles in hematopoiesis, promoting hemopoietic stem cell (HSC) self-renewal, providing proliferative signals for immature progenitors and regulating lineage commitment.
Freeburn, R.W.   +3 more
core   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

open access: yesAdvanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan   +6 more
wiley   +1 more source

Effects of IKKβ or p65 deletion on hematopoiesis.

open access: yes, 2015
Effects of IKKβ or p65 deletion on hematopoiesis.
Albert S. Baldwin Jr. (759315)   +4 more
core   +1 more source

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen   +10 more
wiley   +1 more source

Streptococcal Mannose Phosphotransferase System Component IID Is a Novel RANK‐Binding Osteoclastogenic Factor

open access: yesAdvanced Science, EarlyView.
Streptococcal mannose phosphotransferase system component IID (Man‐PTSIID) is identified as a novel RANK‐binding osteoclastogenic factor. By directly binding to RANK and activating NF‐κB independently of TLR2, Man‐PTSIID drives osteoclastogenesis and inflammatory bone destruction, uncovering an unexpected microbial mechanism underlying streptococcal ...
Chaeyeon Park   +13 more
wiley   +1 more source

Single-cell resolved clonal dynamics in human hematopoiesis and regeneration

open access: yes
SINGLE-CELL RESOLVED CLONAL DYNAMICS IN HUMAN HEMATOPOIESIS AND REGENERATION Single-cell resolved clonal dynamics in human hematopoiesis and regeneration / Nitsch, Lena (Rights reserved) (-
Nitsch, Lena
core  

The Changing Balance Between Osteoblastogenesis and Adipogenesis in Aging and its Impact on Hematopoiesis

open access: yes, 2013
Osteoblasts (OBs) and adipocytes (APs) share a common mesenchymal ancestor. It is now clear that mesenchymal stem cell (MSC) maturation along the OB lineage comes at the expense of adipogenesis and vice versa.
Melissa A. Kacena   +7 more
core   +1 more source

Hematopoiesis [PDF]

open access: yesJournal of Medical Humanities, 2018
openaire   +2 more sources

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