Results 201 to 210 of about 148,177 (294)

Investigating the causal relationship and mediating mechanisms between Clonal hematopoiesis and vitamin D levels: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Liang C, Li M, Sun Z.
europepmc   +1 more source

Tracking of [14C]Polystyrene Nanoplastics in Pregnant Mice

Advanced Science, EarlyView.
This study investigates [14C]polystyrene nanoplastic ([14C]PS) translocation in late‐stage pregnant mice after intranasal (0.5 mg of [14C]PS on GD12, GD14, and GD16, n = 6) and intravenous administration (1.5 mg of [14C]PS on GD16, n = 6). 14C‐radiolabel allows quantitative tracking of unmodified polystyrene nanoplastics.
Olga Khaybullina, Pallavi Sarkhel, Outi M. Keinänen   +2 more
wiley   +1 more source

CDK4/6 inhibition mitigates chemotherapy-induced expansion of TP53-mutant clonal hematopoiesis. [PDF]

Nat Genet
Chan ICC, Zhang P, Pan X, Castro C, Fox N, Lewis AM, Weis K, Cuibus A, Tittley S, Petrone G, Beeler JS, Tran D, Mustion G, Fronick C, Stopsack KH, Cruchaga C, Abdel-Wahab O, Bolton KL.   +17 more
europepmc   +1 more source

Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer [PDF]

, 2019
Bresnick, Emery H, Cao, Miao, Choi, Kyunghee, Hofmann, Inga, Johnson, Kirby D, Keles, Sunduz, Liu, Peng, Mahta, Charu, Soukup, Alexandra A, Wu, Jun, Zhang, Jing, Zheng, Ye, Zhou, Yun   +12 more
core   +1 more source

Peptide‐Incorporated Biomaterials Promote Regeneration of Peripheral Nerve Injuries

Advanced Science, EarlyView.
Peptide‐incorporated biomaterials provide precise, tunable biological cues that mimic functional protein domains to regulate behaviors of neurons, Schwann cells, immune cells, and endothelial cells, thereby enhancing axon elongation, Schwann cell support, inflammatory microenvironment modulation, and vascularization, offering a promising alternative to
Zhiwei Zhao, Jianfeng Liu, Jincheng Li, Di Li, Jianxun Ding, Bin Liu   +5 more
wiley   +1 more source

Cell Lines in Myelodysplastic Syndromes/Neoplasms (MDS) Research: A Review of Existing Models and Their Applications. [PDF]

Int J Mol Sci
Maślińska-Gromadka K, Palusińska M, Łuczak JW, Skopek R, Kraj L, Schenk T, Zelent A, Szymański Ł.   +7 more
europepmc   +1 more source

PAIR: Reconstructing Single‐Cell Open‐Chromatin Landscapes for Transcription Factor Regulome Mapping

Advanced Science, EarlyView.
scATAC‐seq analysis is often constrained by limited sequencing depth, extreme sparsity, and pervasive technical missingness. PAIR is a probabilistic framework that restores scATAC‐seq accessibility profiles by directly modeling the native cell–peak bipartite structure of chromatin accessibility.
Yanchi Su, Qi Qi, Yi Fan, Yubo Wang, Gaoyang Hao, Ka‐Chun Wong, Yunhe Wang, Xiangtao Li   +7 more
wiley   +1 more source

In vivo CRISPR screening identifies SAGA complex members as key regulators of hematopoiesis. [PDF]

Nat Commun
Shankar A, Olender L, Hsu I, Miyauchi M, Pálovics R, Meaker GA, Kaito S, Rizq O, Khoo HM, Bozhilov Y, Igarashi KJ, Bhadury J, Munson C, Mack PK, Tan TK, Rehwinkel J, Iwama A, Wyss-Coray T, Nakauchi H, Haney MS, Wilkinson AC.   +20 more
europepmc   +1 more source

Hematopoiesis [PDF]

Journal of Clinical Pathology, 1985
openaire   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source