Results 201 to 210 of about 157,726 (359)

Homeobox genes in normal hematopoiesis and leukemia [PDF]

, 1992
HJ Lawrence, C Largman
openalex   +1 more source

Enhancing Spatial Transcriptomics via Spatially Constrained Matrix Decomposition with EDGES

Advanced Science, EarlyView.
Imaging‐based spatial transcriptomics technologies are currently limited by their restricted gene detection capacity and low measurement accuracy. Moreover, the insufficient integration of spatial context and single‐cell reference data poses a significant challenge for comprehensive data analysis.
Jinyue Zhao, Jiating Yu, Yuqing Cao, Fan Yuan, Ling‐Yun Wu, Duanchen Sun   +5 more
wiley   +1 more source

Memory CD8+ T cells support the maintenance of hematopoietic stem cells in the bone marrow

Haematologica, 2018
Sulima Geerman, Giso Brasser, Sudeep Bhushal, Fiamma Salerno, Natasja A. Kragten, Mark Hoogenboezem, Gerald de Haan, Monika C. Wolkers, María Fernanda Pascutti, Martijn A. Nolte   +9 more
doaj   +1 more source

Therapy‐Induced ECM Remodeling Creates a Transient Immune Barrier in Residual Melanoma

Advanced Science, EarlyView.
BRAF/MEK inhibition promotes extracellular matrix (ECM) accumulation and remodeling during therapy‐tolerant residual disease, limiting CD8⁺ T cell access to tumor cells. Targeting ECM accumulation restores CD8⁺ T cell infiltration, enhances their intratumoral distribution, and delays therapeutic resistance.
Chia‐Hsin Hsu, Jingyi Chen, Keng‐Jung Lee, Leanne R. Donahue, Danielle Kacaj, Sean P. McDonough, Andrew C. White   +6 more
wiley   +1 more source

Bestatin Treatment of Myelodysplastic Syndromes (MDS) and the Effects of Bestatin on Hematopoiesis in MDS [PDF]

, 1990
Y Uzuka, Yoshiko Saito
openalex   +1 more source

Comparative Cochlear Transcriptomics in Echolocating Bats and Mouse Reveals Hras as Protector Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Comparative cochlear transcriptomics of noise‐exposed bats (Miniopterus fuliginosus) and mice reveals bat‐specific protection mechanisms for noise‐induced hearing loss (NIHL), identifying Hras as a key hub regulator. Functional studies in mice show hair‐cell‐specific Hras overexpression significantly reduced hair‐cell damage and NIHL by activating the ...
Peng Chen, Chenhao Che, Lingjie Wu, Changjie Sun, Dongming Xu, Qinyang Hua, Yunzhong Zhang, Yi‐Quan Tang, Peng Shi, Shan Sun   +9 more
wiley   +1 more source

Red Blood Cell-Mediated Enhancement of Hematopoietic Stem Cell Functions via a Hes1-Dependent Pathway. [PDF]

FASEB J
Yamashita E, Hashimoto S, Abe H, Sudo T, Okuzaki D, Okawa T, Ishii M.   +6 more
europepmc   +1 more source

LACK OF CORRELATION BETWEEN SPLENIC AND MARROW HEMATOPOIESIS FOLLOWING IRRADIATION OR IRRADIATION AND TRANSPLANTATION IN MICE

, 1978
Dane R. Boggs, Sallie S. Boggs
openalex   +1 more source

Expression of tal-1 and GATA-binding proteins during human hematopoiesis [PDF]

, 1993
MA Mouthon, Olivier Bernard, M. T. Mitjavila, Paul‐Henri Roméo, William Vainchenker, D Mathieu-Mahul   +5 more
openalex   +1 more source

Single‐Cell Immune Profiling Reveals Neutrophils Promote Myasthenia Gravis Exacerbation Through BAFF Secretion

Advanced Science, EarlyView.
Single‐cell transcriptomics and clinical data show that during myasthenia gravis (MG) exacerbation, bone marrow mature neutrophils expand and enter blood, with parallel increase of B‐cell activating factor (BAFF)–positive neutrophils. Experimental autoimmune myasthenia gravis (EAMG) confirms a pathogenic interferon‐γ (IFN‐γ)–neutrophil–BAFF axis ...
Zhaoxu Zhang, Jingya Dong, Mengyuan Qiu, Jie Bai, Xufeng Cheng, Xiaodong Song   +5 more
wiley   +1 more source