Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia +16 more
wiley +1 more source
Hematopoietic Aging and Leukemia: Mechanistic and Therapeutic Insights. [PDF]
Li Z +5 more
europepmc +1 more source
Expert Perspectives: Defining and Managing Progressive Pulmonary Fibrosis in Systemic Sclerosis
Systemic sclerosis–associated interstitial lung disease (SSc‐ILD) is one of the leading causes of morbidity and mortality in SSc, affecting up to three‐quarters of patients. The disease course is highly heterogeneous, ranging from indolent, nonprogressive forms to rapidly progressive pulmonary fibrosis (PPF).
Devis Benfaremo +7 more
wiley +1 more source
Revisiting the Origins of Cutaneous T-Cell Lymphoma: A Progenitor-Based Model. [PDF]
Zhang Y, Sokol L.
europepmc +1 more source
IgG Glycosylation‐Dependent CLEC7A Signaling Drives Podocyte Dysfunction in Lupus Nephritis
Objective Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) that can lead to end‐stage kidney disease and increased mortality. IgG from patients with LN displays abnormal glycosylation, contributing to podocyte injury.
Rohit Upadhyay +3 more
wiley +1 more source
Viable <i>Gata2</i> deficient mice exhibit T cell development independent of adult definitive hematopoiesis. [PDF]
Li Y +6 more
europepmc +1 more source
Primary Splenic Classic Hodgkin Lymphoma with Immune Thrombocytopenic Purpura and Extramedullary Hematopoiesis. [PDF]
Elsharawi I +5 more
europepmc +1 more source
Clinical decisions in clonal hematopoiesis: a contemporary review for clinicians. [PDF]
Vanner RJ +4 more
europepmc +1 more source
Cutaneous Extramedullary Hematopoiesis in Primary Myelofibrosis: A Case Report With Rapidly Fatal Outcome. [PDF]
El Bouhmadi A +4 more
europepmc +1 more source
Beyond the JAK2 mutation: The inflammasome, clonal stability, and the thrombotic niche in myeloproliferative neoplasms. [PDF]
Abdelgawwad El-Sehrawy AAM +7 more
europepmc +1 more source

