Results 291 to 300 of about 157,726 (359)

Copper‐Containing Mesoporous Bioactive Glass Nanoparticles: A Novel Radiosensitizer for Nonsmall Cell Lung Cancer

Advanced NanoBiomed Research, EarlyView.
Cu‐MBGNs enhance the efficacy of radiotherapy for nonsmall cell lung cancer (NSCLC), exhibiting selective cytotoxicity toward cancer cells while maintaining minimal toxicity to normal cells. Cu‐MBGNs amplify radiation‐induced ROS through silica‐mediated generation and Cu2+/Cu+ redox catalysis.
Jingyi He, Sihong Ouyang, Xiaofeng Chen, Conghua Xie   +3 more
wiley   +1 more source

Paraspinal Extramedullary Hematopoiesis in a Transfusion-Dependent Beta-Thalassemia Patient: A Case Report. [PDF]

Cureus
Rawashdeh Z, Rawashdeh A, Al-Rahamnah RA, Elghoul YI.   +3 more
europepmc   +1 more source

Identification of a Proteolysis‐Targeting‐Chimera that Addresses Activated Checkpoint Kinase‐1 Reveals its Non‐Catalytic Functions in Tumor Cells

Angewandte Chemie International Edition, EarlyView.
In cancer cells, the induction of DNA replication stress by HU activates CHK1 by autophosphorylation. This leads to cell cycle arrest and recruits the DNA repair protein WRN to promote DNA repair and cell survival. In such cells, addition of the CHK1 inhibitor 9a propels DNA damage and apoptosis.
Ramy Ashry, Mohamed Abdelsalam, Julia Hausen, Christoph Hieber, Yanira Zeyn, Anne‐Christin Sarnow, Matthias Schmidt, Sara Najafi, Ina Oehme, Matthias Bros, Jia‐Xuan Chen, Mario Dejung, Wolfgang Sippl, Oliver H. Krämer   +13 more
wiley   +1 more source

Clonal Hematopoiesis and Cardiovascular Outcomes in Older Women. [PDF]

J Am Coll Cardiol
Ezzat D, Uddin MM, Xue L, Pershad Y, Zhang S, Collins JM, Kitzman JO, Jaiswal S, Desai P, Kooperberg C, Bick AG, Natarajan P, Manson JE, Whitsel EA, Reiner AP, Honigberg MC.   +15 more
europepmc   +1 more source

Review of the anatomical basis for predicting plutonium alpha particle radiation induced osteogenic cancers

The Anatomical Record, EarlyView.
Abstract Plutonium was discovered and first synthesized in the early 1940's. Several isotopes of plutonium are used in nuclear technologies, 238Pu for heat generation and 239Pu for energy production and weapons. Both isotopes emit alpha particles, which pose a significant radiation hazard when incorporated into the body.
Scott C. Miller
wiley   +1 more source

Chromatin factor YY1 controls fetal hematopoietic stem cell migration and engraftment in mice. [PDF]

J Clin Invest
Saka S, Lu Z, Wang Y, Liu P, Singh DK, Lee JP, Palii CG, Alvarez TR, Assumpção AL, You X, Zhang J, Brand M, Atchison ML, Pan X.   +13 more
europepmc   +1 more source

Inside a duck‐billed dinosaur: Vertebral bone microstructure of Huallasaurus (Hadrosauridae), Upper Cretaceous of Patagonia

The Anatomical Record, EarlyView.
Abstract Dinosaurs evolved a unique respiratory system with air sacs that contributed to their evolutionary success. Postcranial skeletal pneumaticity (PSP) has been used to infer the presence of air sac systems in some fossil archosaurs. While unambiguous evidence of PSP is well documented in pterosaurs and post‐Carnian saurischians, it remains absent
Tito Aureliano, Aline M. Ghilardi, Jonatan Kaluza, Agustín G. Martinelli   +3 more
wiley   +1 more source

Radiologic Evaluation of Paranasal Sinuses in Sickle Cell Anemia and Thalassemia: Case-Control Study. [PDF]

Laryngoscope Investig Otolaryngol
Alharbi MA, AlDarwish A, Alamier RM, Omer NE, Alabbad MA, Aljassem AM, ALalwan QM, Althomaly DH, Albaharna HA.   +8 more
europepmc   +1 more source

Trabecular bone ontogeny of the human talus

The Anatomical Record, EarlyView.
Abstract Studies of trabecular ontogeny may provide insight into the factors that drive healthy bone development. There is a growing understanding of how the juvenile skeleton responds to these influences; however, gaps in our knowledge remain. This study aims to identify ontogenetic trabecular patterns and regional changes during development within ...
Rebecca A. G. Reid, Catriona Davies, Craig Cunningham   +2 more
wiley   +1 more source

The TET protein family interactor PROSER1 sustains hematopoietic stem cell function. [PDF]

Blood Adv
Knatko EV, Fleming A, Li X, Crawley P, Budriunaite I, Rasmussen KD.   +5 more
europepmc   +1 more source