Results 201 to 210 of about 1,311,555 (408)
Advanced Science, EarlyView.This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård +19 more
wiley +1 more source
Advanced Science, EarlyView.Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi +15 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley +1 more source
Non-myeloablative autologous hematopoietic stem cell transplantation for systemic lupus erythematosus [PDF]
, 2006 Laisvyde Statkute +11 more
openalex +1 more source
SARS-CoV-2 convalescent plasma therapy in pediatric patient after hematopoietic stem cell transplantation [PDF]
, 2020 Dmitry Balashov +8 more
openalex +1 more source
Mechanisms of Pericyte‐Mediated Cancer Metastasis
Advanced Science, EarlyView.Pericytes play multifarious roles in promoting cancer metastasis by facilitating metastatic cancer cell dissemination, circulating tumor cell survival, tissue extravasation, premetastatic niche formation, and metastatic tumor growth. These cells have intertwined interactions with vascular endothelial cells to modulate cancer cell behavior and ...
Ziheng Guo, Yihai Cao
wiley +1 more source
Blood Development: Hematopoietic Stem Cell Dependence and Independence.
Cell Stem Cell, 2018 E. Dzierzak, A. Bigas
semanticscholar +1 more source
Hematopoietic Stem Cell Transplantation in Multiple Myeloma in the Era of Novel Therapies
, 2019 Khalid Ahmed Al‐Anazi
openalex +2 more sources
High-Dose Chemotherapy with Hematopoietic Stem Cell Transplantation for Patients with Advanced Multiple Myeloma [PDF]
, 2000 Hermann Einsele +5 more
openalex +1 more source
Advanced Science, EarlyView.After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng +9 more
wiley +1 more source