Results 171 to 180 of about 461,308 (260)

Allogeneic Hematopoietic Stem Cell Transplantation for Infant Leukemia: A Single-Center Case Series and Narrative Review. [PDF]

Children (Basel)
Kostareva I, Kirgizov K, Shubina I, Stepanyan N, Batmanova N, Valiev T, Kiselevsky M, Varfolomeeva S.   +7 more
europepmc   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation in Adult Acute Myeloid Leukemia: A Systematic Review. [PDF]

Cureus
Mohamed Ahmed AB, Elagab EA, Abdalla Ahmed EA, Hassan Mahgoub NE, Dawod Faky FS, Shamina NA, Subahi N.   +6 more
europepmc   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

Prenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear, Beltran Borges, Billie R. Lianoglou, Tony Lum, Emma Canepa, Jennifer L. Cohen, Julia E. H. Brown, Akos Herzeg   +7 more
wiley   +1 more source

Quality of life and mood predict posttraumatic stress disorder after hematopoietic stem cell transplantation

Cancer, 2016
A. El-Jawahri, Harry Vandusen, L. Traeger, J. Fishbein, Tanya Keenan, E. Gallagher, J. Greer, W. Pirl, V. Jackson, T. Spitzer, Yi-Bin Chen, J. Temel   +11 more
semanticscholar   +1 more source

Symptoms of depression and anxiety in patients with transfusion-dependent thalassemia after hematopoietic stem cell transplantation: a single-center study. [PDF]

Ther Adv Hematol
Liang X, Huang Y, Yang G, Shi L, Liu L, Xiao H, Dai J, Wei Z, Pan L, Gan Z, Lin Y, Yao Y, Tang Y, Huang H, Zhou X, Lai Y, Liu R.   +16 more
europepmc   +1 more source

Clinical characteristics and risk factors of severe bocavirus‐positive pneumonia in children and a literature review

Pediatric Discovery, EarlyView.
The study explored the clinical characteristics and risk factors of HBoV‐positive severe pneumonia in children. These findings indicate that HBoV can be identified in respiratory samples from children with severe pneumonia, denoting its role as a viral pathogen in hospitalized children with this condition.
Jing Liao, Zhongying Yang, Yu He, Jianhua Wei, Luo Ren, Enmei Liu, Na Zang   +6 more
wiley   +1 more source

Microbiome-based prediction of allogeneic hematopoietic stem cell transplantation outcome. [PDF]

Genome Med
Shtossel O, Eshel A, Fried S, Geva M, Danylesko I, Yerushalmi R, Shem-Tov N, Fein JA, Fabbrini M, Shimoni A, Turjeman S, Louzoun Y, Nagler A, Koren O, Shouval R.   +14 more
europepmc   +1 more source

Physiologically‐Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Pediatric extrapolation strategies issued by health authorities have streamlined pediatric drug development and reduced the unnecessary burden of conducting pediatric clinical studies. In line with these strategies, physiologically based pharmacokinetic (PBPK) models have been utilized extensively for initial dosing regimen and sampling ...
James W. T. Yates, Michael Zientek, Kunal S. Taskar, Wen Lin, Tycho Heimbach, Stefan Willmann, Jessica Rehmel, Neil Parrott, Michael Hanley, Justine Badee, Yuan Chen, Susan Cole, Loeckie De Zwart, Sebastian Haertter, Rongrong Jiang, Masakatsu Kotsuma, Guiqing Liang, Yu‐Wei Lin, Jing Liu, Ying Ou, Juliane Rascher, Naveed A. Shaik, Jan Wahlstrom, Xiaofeng Wang, Guangqing Xiao, Ka Lai Yee, S. Y. Amy Cheung   +26 more
wiley   +1 more source

Hematopoietic stem cell transplantation in immunocompetent hosts without radiation or chemotherapy

Science Translational Medicine, 2016
Akanksha Chhabra, A. Ring, K. Weiskopf, Peter J. Schnorr, S. Gordon, Alan C. Le, Hye-Sook Kwon, N. G. Ring, J. Volkmer, P. Ho, Serena Tseng, I. Weissman, J. Shizuru   +12 more
semanticscholar   +1 more source