Results 291 to 300 of about 540,232 (408)

CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy

VIEW, EarlyView.
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma, Junxin Chen, Yuan Du, Zhihao Cao, Weizhi Ji, Yuyu Niu, Zebin Yang   +6 more
wiley   +1 more source

Healthcare Resource Use and Costs of Allogeneic Hematopoietic Stem Cell Transplantation Complications: A Scoping Review. [PDF]

Curr Oncol
Kim NV, McErlean G, Yu S, Kerridge I, Greenwood M, De Abreu Lourenco R.   +5 more
europepmc   +1 more source

Immune Reconstitution after Allogeneic Hematopoietic Stem Cell Transplantation: Time To T Up the Thymus

Journal of Immunology, 2017
M. Chaudhry, E. Velardi, F. Malard, M. V. D. van den Brink   +3 more
semanticscholar   +1 more source

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes, Rishi S. Kotecha, Derek J. Roebuck   +2 more
wiley   +1 more source

Effect of Hematopoietic Stem Cell Transplantation Regimen on Tacrolimus Pharmacokinetics. [PDF]

Curr Ther Res Clin Exp
Oku H, Yoshida S, Hotta T, Muroi H, Fukushima K, Irie K, Hirano T, Shimomura Y, Ishikawa T, Ikesue H, Muroi N, Hashida T, Sugioka N.   +12 more
europepmc   +1 more source

Incidence and outcome of bacterial and fungal infections following nonmyeloablative compared with myeloablative allogeneic hematopoietic stem cell transplantation: A matched control study [PDF]

, 2002
Christian Junghanß, Kieren A. Marr, Rachel A. Carter, Brenda M. Sandmaier, Michael B. Maris, David G. Maloney, Thomas R. Chauncey, Peter A. McSweeney, Rainer Storb   +8 more
openalex   +1 more source

Age‐Dependent Clonal Expansion of Non–Sperm‐Forming Spermatogonial Stem Cells in Mouse Testes

Aging Cell, EarlyView.
We found that GFRα1+ spermatogonial stem cells (SSCs) with reduced Egr4 and Cops5 expression did not form spermatids in mouse testes. Furthermore, the proportion of their clones relative to the total SSC clones increased and their distribution area expanded in old mice.
Terumichi Kawahara, Shinnosuke Suzuki, Toshinori Nakagawa, Yuki Kamo, Miki Kanouchi, Miyako Fujita, Maki Hattori, Atsuko Suzuki, Kentaro Tanemura, Shosei Yoshida, Kenshiro Hara   +10 more
wiley   +1 more source

Hematopoietic stem cell transplantation for multiple sclerosis: no inflammation, no response. [PDF]

Eur J Neurol
Burt RK, Alexander T, EBMT Autoimmune Diseases Working Party (ADWP).   +2 more
europepmc   +1 more source

Thrombopoietin expands hematopoietic stem cells after transplantation [PDF]

, 2002
Norma E. Fox, Greg Priestley, Thalia Papayannopoulou, Kenneth Kaushansky   +3 more
openalex   +1 more source

Pyrroloquinoline Quinone Reprograms the Single‐Cell Landscape of Immune Aging in Hematopoietic Immune System

Aging Cell, EarlyView.
This study demonstrates that aging induces oxidative stress and inflammation in the hematopoietic immune system, resulting in immune homeostasis dysfunction, including alterations in B cells and hematopoietic stem cells, senescent cells (SnCs) accumulation, and senescence‐associated secretory phenotypes (SASPs) production. Notably, the study highlights
Xiuxing Liu, Chun Zhang, Jianjie Lv, Yidan Liu, Chenyang Gu, Yuehan Gao, Wen Ding, Hui Chen, Nanwei Xu, Hongbin Yin, Wenru Su, Zhuping Xu   +11 more
wiley   +1 more source