Results 311 to 320 of about 540,232 (408)

Adaptive dosing of high‐dose busulfan in real‐world adult patients undergoing haematopoietic cell transplant conditioning

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 1171-1181, April 2025.
Aim To evaluate the effectiveness of a Bayesian adaptive dosing strategy in achieving target busulfan exposure in adult patients undergoing haematopoietic cell transplantation (HCT). Methods This study included 71 adult patients scheduled to receive high‐dose busulfan. Busulfan was administered to achieve a cumulative area under the curve (AUC) of 66.0 
Dorian Protzenko   +6 more
wiley   +1 more source

Characteristics and Outcome of Patients After Allogeneic Hematopoietic Stem Cell Transplantation Treated With Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome*

open access: yesCritical Care Medicine, 2017
P. Wohlfarth   +18 more
semanticscholar   +1 more source

Killing several birds with one stone: A multi‐indication population pharmacokinetic model and Bayesian estimator for enteric‐coated mycophenolate sodium

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 5, Page 1396-1408, May 2025.
Abstract Aims Mycophenolic acid (MPA), the active component of enteric‐coated mycophenolate sodium (EC‐MPS), exhibits highly variable pharmacokinetics. Only a few population pharmacokinetic (popPK) models and Bayesian estimators (MAP‐BE) exist for estimating MPA AUC and all in renal transplantation.
Yeleen Fromage   +6 more
wiley   +1 more source

Pharmacokinetic characterization and exposure–response relationship of crovalimab in the COMMODORE 1, 2 and 3 and COMPOSER trials of patients with paroxysmal nocturnal haemoglobinuria

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 5, Page 1479-1490, May 2025.
Abstract Aims Crovalimab is a novel C5 inhibitor administered first intravenously and then subcutaneously in patients with paroxysmal nocturnal haemoglobinuria (PNH) naive to complement inhibition or switching from eculizumab or ravulizumab. Crovalimab showed efficacy and safety comparable to eculizumab in the pivotal COMMODORE 2 and supporting studies.
Valérie Cosson   +19 more
wiley   +1 more source

Late Relapse After Autologous Hematopoietic Stem Cell Transplantation in AQP4-IgG-Positive NMOSD.

open access: yesJAMA Netw Open
Vorasoot N   +9 more
europepmc   +1 more source

Hematopoietic stem cell transplantation and immunosuppressive therapy: implications of clonal haematopoiesis. [PDF]

open access: yesAnn Hematol
Tan Z   +12 more
europepmc   +1 more source

OP0038 Autologous hematopoietic stem cells (hsc) transplantation in scleroderma and myositis

open access: bronze, 2001
D Farge   +11 more
openalex   +1 more source

A critical review of management of allogeneic transplant‐eligible adults with Ph+ acute lymphoblastic leukaemia

open access: yesBritish Journal of Haematology, EarlyView.
Proposed management of newly diagnosed Philadelphia chromosome‐positive (Ph+) acute lymphoblastic leukaemia (ALL) in transplant‐eligible patients. Suggested considerations when deciding the treatment pathway available to a newly diagnosed Ph+ ALL patient that would be deemed transplant eligible. Summary Acute lymphoblastic leukaemia (ALL) in 20%–30% of
Naranie Shanmuganathan, Andrew Grigg
wiley   +1 more source

Outcomes in patients undergoing hematopoietic stem cell transplantation for myelodysplastic syndromes. [PDF]

open access: yesBlood Cell Ther
Karumathil S   +11 more
europepmc   +1 more source

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