Results 341 to 350 of about 540,232 (408)

Refractory myasthenia gravis treated with autologous hematopoietic stem cell transplantation. [PDF]

Ann Clin Transl Neurol
Beland B, Storek J, Quartermain L, Hahn C, Pringle CE, Bourque PR, Kennah M, Kekre N, Bredeson C, Allan D, Jamani K, White C, Atkins H.   +12 more
europepmc   +1 more source

The IKZF1 N159S mutation is associated with poor outcome and a distinct molecular profile in adult patients with AML

British Journal of Haematology, Volume 206, Issue 5, Page 1373-1379, May 2025.
Summary IKZF1 mutations are recurrent alterations in acute myeloid leukaemia (AML), and hotspot point mutation, N159S, has recently been associated with unique gene expression and adverse risk. To better understand the molecular and clinical associations of IKZF1 N159S‐mutated AML, we performed a pooled analysis of 4136 AML patients.
Sebastian Stasik, Jan‐Niklas Eckardt, Christoph Röllig, Claudia D. Baldus, Uwe Platzbecker, Hubert Serve, Carsten Müller‐Tidow, Kerstin Schäfer‐Eckart, Martin Kaufmann, Stefan W. Krause, Tim Sauer, Mathias Hänel, Andreas Neubauer, Gerhard Ehninger, Martin Bornhäuser, Johannes Schetelig, Jan M. Middeke, Christian Thiede, on behalf of the Study Alliance Leukemia (SAL)   +18 more
wiley   +1 more source

Markers of Kidney Injury: Proenkephalin A and Uromodulin, but Not Dickkopf-3, Are Elevated in Patients After Hematopoietic Stem Cell Transplantation. [PDF]

Int J Mol Sci
Kaszyńska A, Kępska-Dzilińska M, Karakulska-Prystupiuk E, Tomaszewska A, Basak GW, Żórawski M, Jakubowska Z, Małyszko J.   +7 more
europepmc   +1 more source

High-dose immunosuppression and hematopoietic stem cell transplantation in autoimmune disease: Clinical review

, 2002
Harry Openshaw, Richard A. Nash, Peter A. McSweeney   +2 more
openalex   +1 more source

Iron trapping in macrophages reshapes the homeostasis of the haematopoietic system

British Journal of Haematology, Volume 206, Issue 5, Page 1485-1496, May 2025.
Deletion of ferroportin (Fpn) in myeloid cells results in iron trapping in macrophages and reshapes whole haematopoiesis with ageing. Impaired local iron supply to bone marrow (BM) leads to anaemia and microcytaemia, unbalanced megakaryopoiesis versus erythropoiesis and reduced BM cells starting from haematopoietic stem cells.
Laura Crisafulli, Margherita Correnti, Elena Gammella, Elisa De Camilli, Matteo Brindisi, Eleonora Palagano, Chiara Milanesi, Gabriele Todisco, Matteo G. Della Porta, Cristina Sobacchi, Gaetano Cairo, Francesca Ficara, Stefania Recalcati   +12 more
wiley   +1 more source

Advances in hematopoietic stem cell transplantation for autoimmune diseases. [PDF]

Heliyon
Xu Y, Wang X, Hu Z, Huang R, Yang G, Wang R, Yang S, Guo L, Song Q, Wei J, Zhang X.   +10 more
europepmc   +1 more source

Indirect presentation of mismatched human leukocyte antigen‐B associates with outcomes of cord blood transplantation

British Journal of Haematology, Volume 206, Issue 5, Page 1406-1417, May 2025.
This study analysed 1498 single‐unit cord blood transplantation (CBT) cases (2000–2018) to evaluate the impact of mismatched human leukocyte antigen (HLA) immunogenicity. Results highlighted that Class I epitopes from recipient‐mismatched HLA‐B were associated with higher transplantation‐related mortality (TRM) and lower neutrophil engraftment ...
Takeshi Sugio, Kohta Miyawaki, Naoyuki Uchida, Matthias Niemann, Eric Spierings, Kyohei Mori, Yuju Ohno, Tetsuya Eto, Yasuo Mori, Goichi Yoshimoto, Yoshikane Kikushige, Yuya Kunisaki, Shinichi Mizuno, Koji Nagafuji, Hiromi Iwasaki, Tomohiko Kamimura, Ryosuke Ogawa, Toshihiro Miyamoto, Shuichi Taniguchi, Koichi Akashi, Koji Kato   +20 more
wiley   +1 more source

Optimizing Haploidentical Hematopoietic Stem Cell Transplantation: Enhancing Outcomes in Hematologic Malignancies in Resource-Limited Settings. [PDF]

J Blood Med
Owattanapanich W, Karoopongse E, Kittivorapart J, Meeudompong U, Sathapanapitagkit N, Kungwankiattichai S, Vittayawacharin P, Jianthanakanon J, Donsakul N, Bundhit R, Kongsomchit C, Poonmee N, Luangtrakool P, Warindpong T, Chamsai S, Bintaprasit W, Atakulreka S, Kunacheewa C.   +17 more
europepmc   +1 more source

How low can we go? Comparison of liberal and restrictive red cell transfusion thresholds in paediatric allogeneic haematopoietic stem cell transplantation: A randomized multicentre feasibility trial

British Journal of Haematology, EarlyView.
Optimal red blood cell transfusion thresholds for children with bone marrow failure are uncertain. Children may be able to safely tolerate lower haemoglobin thresholds, thereby reducing transfusions, which have risks. This study in paediatric allogeneic haematopoietic stem cell transplant aimed to assess feasibility of recruitment and protocol ...
H. V. New, E. Sanderson, V. Hopkins, H. Thomas, A. Gassas, M. Adams, B. Gibson, K. Patrick, R. Wynn, L. Hoole, H. Smethurst, M. Lobo‐Clarke, L. Smith, A. Mora, S. J. Stanworth   +14 more
wiley   +1 more source