Results 351 to 360 of about 540,232 (408)

The wider perspective: Barriers and recommendations for transfusion support for patients with sickle cell disease in low‐ and middle‐income countries

open access: yesBritish Journal of Haematology, EarlyView.
Globally, sickle cell disease (SCD) is the most common inherited haemoglobinopathy. The highest burden of SCD is encountered in low‐ and middle‐income countries (LMICs), most of which lack the resources to contend with the disease. Blood transfusion remains central to the emergent treatment and prevention of complications of SCD.
Jeremy W. Jacobs   +13 more
wiley   +1 more source

Myeloid neoplasm inspired intensive therapy in VEXAS syndrome: A single‐centre experience

open access: yesBritish Journal of Haematology, EarlyView.
Summary There is still no standard of care and unmet medical needs in refractory/advanced VEXAS (vacuoles in myeloid progenitors, E1 ubiquitin activating enzyme, X‐linked, autoinflammatory manifestations and somatic) syndrome with or without associated haematological neoplasm.
Maël Heiblig   +5 more
wiley   +1 more source

Comparison of severe aplastic anaemia and lower risk hypoplastic myelodysplastic neoplasms: Critical role of megakaryocyte count in distinguishing aplastic anaemia from myelodysplastic neoplasms

open access: yesBritish Journal of Haematology, EarlyView.
In our central morphological review system, megakaryocyte counts are prioritized alongside BM cellularity to differentiate between AA and MDS. A retrospective analysis of patients with SAA and those with LR‐hMDS, registered in that system, revealed a significant difference in outcomes.
Tomoya Maeda   +25 more
wiley   +1 more source

Case study: Acute plasmoblastic leukemia presentation following effective haploidentical hematopoietic stem cell transplantation therapy. [PDF]

open access: yesJ Int Med Res
Karabekov A   +7 more
europepmc   +1 more source

Distinct characteristics and social determinants in adult T‐cell leukaemia/lymphoma patients at a tertiary cancer centre in Canada

open access: yesBritish Journal of Haematology, EarlyView.
Adult T‐cell leukaemia/lymphoma (ATLL) is a rare, aggressive cancer linked to HTLV‐1, with poor outcomes. We analysed 79 ATLL patients (1993–2023) at our institution. The median age at diagnosis was 47 years, with 72% of patients of Caribbean origin. Median progression‐free and overall survival were 10.2 and 16.2 months respectively. CNS involvement at
Tomohiro Aoki   +11 more
wiley   +1 more source

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