Results 41 to 50 of about 382,649 (338)

Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually

open access: yesBone Marrow Transplantation, 2016
A record number of 40 829 hematopoietic stem cell transplantation (HSCT) in 36 469 patients (15 765 allogeneic (43%), 20 704 autologous (57%)) were reported by 656 centers in 47 countries to the 2014 survey. Trends include: continued growth in transplant
Jakob R. Passweg   +15 more
semanticscholar   +1 more source

The effects of intestinal tract bacterial diversity on mortality following allogeneic hematopoietic stem cell transplantation.

open access: yesBlood, 2014
Highly diverse bacterial populations inhabit the gastrointestinal tract and modulate host inflammation and promote immune tolerance. In allogeneic hematopoietic stem cell transplantation (allo-HSCT), the gastrointestinal mucosa is damaged, and colonizing
Y. Taur   +14 more
semanticscholar   +1 more source

Hematopoietic stem cell transplantation in Egypt [PDF]

open access: yesBone Marrow Transplantation, 2008
Hematopoietic SCT is now an established treatment modality with definitive indications for many hematological disorders. However, this line of treatment requires tremendous resources, and it becomes increasingly difficult for transplanters practicing in the developing world to reconcile the difference between what is possible and what is available.
A Sobhy   +7 more
openaire   +3 more sources

Hematopoietic Stem Cell Transplantation in Inborn Errors of Metabolism

open access: yesFrontiers in Pediatrics, 2019
Hematopoietic stem cell transplantation (HSCT) has been established as an effective therapy for selected inborn errors of metabolism. The success of HSCT in metabolic disease is best exemplified through the treatment of Hurler's syndrome, a lysosomal ...
E. Y. Tan   +3 more
semanticscholar   +1 more source

Acute Kidney Injury and CKD associated with Hematopoietic Stem Cell Transplantation.

open access: yesAmerican Society of Nephrology. Clinical Journal, 2019
Hematopoietic stem cell transplantation is a life-saving therapy for many patients with cancer, as well as patients with some nonmalignant hematologic disorders, such as aplastic anemia, sickle cell disease, and certain congenital immune deficiencies ...
A. Renaghan   +5 more
semanticscholar   +1 more source

Hematopoietic Stem Cell Transplantation

open access: yes, 2016
Hematopoietic stem cell transplantation offers patients the only prospect of long-term survival for a substantial variety of otherwise incurable malignant neoplasms as well as selected non-neoplastic conditions. This therapeutic modality, however, carries significant risks and is associated with a wide range of complications affecting not only the bone
Chelsea Maedler-Kron   +2 more
openaire   +2 more sources

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Haploidentical donor is preferred over matched sibling donor for pre-transplantation MRD positive ALL: a phase 3 genetically randomized study

open access: yesJournal of Hematology & Oncology, 2020
Background Previous reports suggest a benefit associated with haploidentical donor transplantation (HIDT) compared to matched sibling donor transplantation (MSDT) in certain contexts, and the choice of optimal candidates warrants further investigation ...
Ying-Jun Chang   +14 more
doaj   +1 more source

Monitoring of post-transplant MLL-PTD as minimal residual disease can predict relapse after allogeneic HSCT in patients with acute myeloid leukemia and myelodysplastic syndrome

open access: yesBMC Cancer, 2022
Background The mixed-lineage leukemia (MLL) gene is located on chromosome 11q23. The MLL gene can be rearranged to generate partial tandem duplications (MLL-PTD), which occurs in about 5-10% of acute myeloid leukemia (AML) with a normal karyotype and in ...
Jun Kong   +11 more
doaj   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

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