Results 351 to 360 of about 1,175,170 (409)
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New England Journal of Medicine, 1979
(First of Three Parts) IN man, most tissues consist primarily of differentiated cells that normally show little evidence of proliferation and self-renewal.
P, Quesenberry, L, Levitt
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(First of Three Parts) IN man, most tissues consist primarily of differentiated cells that normally show little evidence of proliferation and self-renewal.
P, Quesenberry, L, Levitt
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Clinical Orthopaedics and Related Research, 2000
Hematopoietic stem cells are rare cells found in the bone marrow, peripheral blood, placenta, and elsewhere that sustain the hematopoietic system. The current review will focus on the evolving views of the biology of these cells. Because hematopoietic stem cells have been studied and transplanted for several decades, lessons learned from studying these
C, Smith, B, Storms
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Hematopoietic stem cells are rare cells found in the bone marrow, peripheral blood, placenta, and elsewhere that sustain the hematopoietic system. The current review will focus on the evolving views of the biology of these cells. Because hematopoietic stem cells have been studied and transplanted for several decades, lessons learned from studying these
C, Smith, B, Storms
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Cancer Investigation, 2002
In the broadest sense, stem cells are primitive cells endowed with extensive capacities to develop and differentiate into functional and mature tissues or organs.
Paul, Schwarzenberger +2 more
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In the broadest sense, stem cells are primitive cells endowed with extensive capacities to develop and differentiate into functional and mature tissues or organs.
Paul, Schwarzenberger +2 more
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Current Opinion in Immunology, 2014
Aging is organized in a hierarchy, in which aging of cells results in aged tissues, ultimately limiting lifespan. For organ systems that also in the adult depend on stem cells for tissue homeostasis like the hematopoietic system that forms immune cells, it is believed that aging of the stem cells strongly contributes to aging-associated dysfunction. In
Hartmut, Geiger +2 more
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Aging is organized in a hierarchy, in which aging of cells results in aged tissues, ultimately limiting lifespan. For organ systems that also in the adult depend on stem cells for tissue homeostasis like the hematopoietic system that forms immune cells, it is believed that aging of the stem cells strongly contributes to aging-associated dysfunction. In
Hartmut, Geiger +2 more
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Characterization of Hematopoietic Stem Cells
Annals of the New York Academy of Sciences, 1995On the basis of density-separated mononuclear cells isolated from bone marrow, peripheral blood, and cord blood, we have repeatedly shown good correlation between two-color flow cytometric (FACS) CD34 analysis and colony formation in the clonogenic assay.
G, Fritsch +7 more
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Pediatrics, 2004
The hematopoietic system of the young child acquires, through time, the ability to cope with exposure to a number of environmental toxins and infectious agents. Occasionally, severe aplastic anemia occurs secondary to exposure to some of these toxins or infectious agents.
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The hematopoietic system of the young child acquires, through time, the ability to cope with exposure to a number of environmental toxins and infectious agents. Occasionally, severe aplastic anemia occurs secondary to exposure to some of these toxins or infectious agents.
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Birth Defects Research Part C: Embryo Today: Reviews, 2003
AbstractConsiderable effort has been made in recent years in defining the embryonic origin of the hematopoietic stem cell (HSC). Using transgenic mouse models, a number of genes that regulate the formation, selfârenewal, or differentiation of HSCs have been identified. Of particular interest, it has recently been shown that key regulators of definitive
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AbstractConsiderable effort has been made in recent years in defining the embryonic origin of the hematopoietic stem cell (HSC). Using transgenic mouse models, a number of genes that regulate the formation, selfârenewal, or differentiation of HSCs have been identified. Of particular interest, it has recently been shown that key regulators of definitive
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Current Biology, 1992
Recent studies indicate that hematopoietic stem cells that provide long-term reconstitution can be separated from more mature hematopoietic cells that provide radioprotection and short-term repopulation. With these findings it is now possible to design assays that will specifically measure long-term repopulating stem cells, as well as to develop ...
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Recent studies indicate that hematopoietic stem cells that provide long-term reconstitution can be separated from more mature hematopoietic cells that provide radioprotection and short-term repopulation. With these findings it is now possible to design assays that will specifically measure long-term repopulating stem cells, as well as to develop ...
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2013
Hematopoietic stem cells represent the most studied and understood adult stem cell, and have consequently set the trends for the investigation of a wide array of stem cells, while their clinical use for over half a century and ever improving efficacy encourages the view that stem cell therapy will 1 day be useful in the treatment of a whole host of ...
Mary L. Clarke, Jonathan Frampton
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Hematopoietic stem cells represent the most studied and understood adult stem cell, and have consequently set the trends for the investigation of a wide array of stem cells, while their clinical use for over half a century and ever improving efficacy encourages the view that stem cell therapy will 1 day be useful in the treatment of a whole host of ...
Mary L. Clarke, Jonathan Frampton
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Hematopoietic stem cell expansion
Transfusion Science, 1997This review addresses two issues: (1) cytokine-mediated expansion of functional end cells for the abrogation of short term neutropenia and thrombopenia following high dose chemotherapy and (2) cytokine-driven increase in absolute numbers of functional stem cells.
A, Rice, J, Ripoche, J, Reiers
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