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Age and the Hematopoietic System
Journal of the American Geriatrics Society, 1986The aging process is characterized by a decline in the function of many organ systems. Changes that occur in cardiovascular, endocrine, and immune function with aging have been described extensively. The bone marrow clearly plays an important role in normal physiology, being responsible for oxygen delivery to tissues as well as participating in normal ...
D A, Lipschitz, K B, Udupa
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Hematopoietic Stem Cells and the Aging Hematopoietic System
Seminars in Hematology, 2008The etiology of the age-associated pathophysiological changes of the hematopoietic system including the onset of anemia, diminished adaptive immune competence, and myelogenous disease development are underwritten by the loss of normal homeostatic control.
Roi, Gazit +2 more
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Aging of the hematopoietic system
Current Opinion in Hematology, 2013Aging of the hematopoietic system is associated with myeloid malignancies, anemia and immune dysfunction. As hematopoietic stem cells (HSCs) generate all cells of the hematopoietic system, age-associated changes in HSCs may underlie many features of the aged hematopoietic system.
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Development of the hematopoietic system in the mouse
Experimental Hematology, 1999Introduction The hematopoietic system is established early in embryonic development and functions throughout fetal and adult life to provide a continuous supply of mature blood cells to the embryo, the fetus, and the adult. Maturation of the hematopoietic system in ontogeny represents a succession of developmental programs beginning in the yolk sac and
G, Keller, G, Lacaud, S, Robertson
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1979
Anemia is probably the commonest effect of nutritional deficiency in human beings and has certainly been the most extensively studied. Iron deficiency is widely recognized as the most important cause of anemia in the world (Finch, 1969; Beaton, 1974).
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Anemia is probably the commonest effect of nutritional deficiency in human beings and has certainly been the most extensively studied. Iron deficiency is widely recognized as the most important cause of anemia in the world (Finch, 1969; Beaton, 1974).
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