Results 1 to 10 of about 310 (139)

Development of Novel Tetrapyrrole Structure Photosensitizers for Cancer Photodynamic Therapy [PDF]

Bioengineering, 2022
The effectiveness of photodynamic therapy (PDT) is based on the triad effects of photosensitizer (PS), molecular oxygen and visible light on malignant tumors.
Natalia Plekhova, Olga Shevchenko, Oksana Korshunova, Aleksandra Stepanyugina, Ivan Tananaev, Vladimir Apanasevich   +5 more
doaj   +2 more sources

Hematoporphyrin phototherapy of cancer [PDF]

Radiotherapy and Oncology, 1986
Hematoporphyrin phototherapy of cancer is a new modality for cancer diagnosis and treatment that is currently undergoing clinical trials worldwide. A variety of tumors have been studied, e.g., breast (mostly recurrent skin), lung, bladder, eye, head and neck, gynecological and brain.
Berns, Michael W, Wile, Alan G
openaire   +4 more sources

Teraphtal (sodium salt of cobalt 4,5-carboxyphthalocyanine) Decreases Sensitivity of Tumor Cells to Anthracycline Antibiotics and Mitoxantrone in Vitro

Клиническая онкогематология, 2018
Background. Anthracycline antibiotics (AA) are widely used in clinical oncohematology. As is well known АА cytotoxicity diminishes in the presence of hemin (FePPIX), an endogenous metalloporphyrine. Aim.
Tat’yana Aleksandrovna Sidorova, O. O. Ryabaya, V. V. Tatarskii, D. A. Khochenkov, E. S. Ivanova, O. L. Kaliya   +5 more
doaj   +1 more source

Interaction of Hematoporphyrin with Lipid Membranes

The Journal of Physical Chemistry B, 2012
Natural or synthetic porphyrins are being used as photosensitizers in photodiagnosis (PD) and photodynamic therapy (PDT) of malignancies and some other diseases. Understanding the interactions between porphyrins and cell membranes is therefore important to rationalize the uptake of photosensitizers and their passive transport through cell membranes. In
M. Stepniewski, M. Kepczynski, D. Jamroz, M. Nowakowska, S. Rissanen, I. Vattulainen, and T. Rog   +6 more
openaire   +5 more sources

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

The effect of photodynamic therapy in head and neck cancer: A comprehensive review of in vivo models

Photochemistry and Photobiology, EarlyView.
This review evaluates Photodynamic Therapy (PDT) in in vivo head and neck cancer models. PDT effectively generates ROS, reducing tumor growth, cell proliferation and angiogenesis while enhancing survival and immune responses. However, methodological heterogeneity highlights the urgent need for standardized dosimetric protocols to ensure reproducibility
Bibiana Padilha de Menezes da Silva, Rebeca Barros Nascimento, Giovanna Lopes Carvalho, Rebeca Boltes Cecatto, Maria Stella Moreira, Maria Fernanda Setúbal Destro Rodrigues   +5 more
wiley   +1 more source

Nanomaterial‐Mediated Radiotherapy–Immunotherapy Combinations: Breaking Immunosuppression and Revolutionizing Cancer Treatment

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Nanomaterials integrate radiotherapy and immunotherapy by enhancing radiosensitivity, remodeling the immunosuppressive tumor microenvironment, and promoting systemic antitumor immunity. This review summarizes the latest strategies of nanomaterial‐mediated combinations (RT, immunotherapy, IRT) and highlights future directions for overcoming clinical ...
Peijie Li, Xiangqin Wang, Sisi He, Hu Ma
wiley   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, Volume 4, Issue 2, June 2026.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source