Results 31 to 40 of about 414 (184)
Novel Photodynamic Therapy Agents: Biochemical Analysis [PDF]
Bioinorganic photochemistry is a rapidly advancing research area in the field of bioinorganic chemistry. This project seeks to build upon the growing field by synthesizing and analyzing new photodynamic therapy (PDT) agents.
Pullen, Eboni D
core +1 more source
Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa +4 more
wiley +1 more source
Effect of calcium on the vasoactive response of arterioles to light during fluorescent intravital microscopy of the tibialis anterior muscle of the hamster [PDF]
Arterioles may undergo a transient vasoactive response when exposed to light during fluorescent intravital microscopy. We hypothesized that the type and frequency of the vasoactive responses by arterioles to light is calcium dependent.
Gardner, Ane K., Messina, Louis M.
core +1 more source
Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan +5 more
wiley +1 more source
In Vivo Efficacy of Zinc Phthalocyanine Nanocarriers IN Photodynamic Therapy of Cancer
Zinc phthalocyanines are photosensitizing agents used in photodynamic therapy. Their incorporation into nanosystems enables their encapsulation, targeting, and functionalization, optimizing their therapeutic activity. The results highlight their therapeutic potential, reinforcing their relevance as an innovative strategy in cancer treatment and as a ...
Adrian Lima Roberto +4 more
wiley +1 more source
One of the most difficult areas of both human and veterinary medicine today is the treatment of neoplastic disease. numerous techniques and agents have been used in this field but none are totally effective.
Grier, Ronald L., Ihle, Sherri L.
core +2 more sources
Implanted Miniature Light Devices for Phototherapeutics
Modern phototherapeutics has many attractive features; however, the shallow penetration of light into skin and tissue is an inherent physical limitation that restricts usage to superficial sites of disease. To mitigate this major problem, researchers and clinicians are actively developing miniature implanted light devices that can be implanted within a
Hailey S. Sanders +5 more
wiley +1 more source
Nanoencapsulated Drug-Carrying System for Photodynamic Antimicrobial Chemotherapy (PACT) [PDF]
The purpose of this study is to develop nanoparticulate drug-carrying systems that are capable of directly delivering photodynamic antimicrobial agents to treat patients with chronic wounds.
Kalapala, Gopala Krishna Murthy
core +1 more source
FUNCTIONALIZED SUB-10 NM SILICA METHYLENE BLUE NANOPHOTOSENSITIZERS [PDF]
Photodynamic therapy (PDT) presents an alternative non-invasive therapeutic modality for the treatment of cancer and other diseases. PDT relies on cytotoxic singlet oxygen that is locally generated through energy transfer between a photosensitizer and ...
Li, Songying
core +1 more source
FLASH‐PDT uses strongly‐absorbing photosensitizers and pulsed lasers to saturate the photosensitizer absorption at ≈1‐cm tissue depths. This allows for the generation of [ROS] above the necrosis threshold level for tumors, while maintaining [ROS] in peritumoral tissues below that threshold, even when the tumor‐to‐peritumoral tissue ratio is as low as 2.
Luis G. Arnaut +3 more
wiley +1 more source

