Results 11 to 20 of about 310 (139)

Theranostic Advancements in Brain Cancer: Promising Approaches for Emerging Therapy

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Strategies for improving intra‐arterial administration (A) and photodynamic therapy in brain cancer (B). Improving intra‐arterial (IA) administration and photodynamic therapy (PDT) for brain cancer involves enhancing tumor targeting and breaching the blood–brain barrier (BBB). Key strategies include super selective catheterization, using osmotic agents
Bipraban Khanra, Manoj Kumar Sarangi
wiley   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 20, 27 May 2026.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

Ultrasound‐Responsive Engineered Bacteria for Targeted Cancer Therapy: Strategies, Mechanisms, and Applications

open access: yesAdvanced Science, Volume 13, Issue 20, 9 April 2026.
This review elucidates URB design strategies, including genetic and physicochemical modifications, while dissecting the synergistic mechanisms governing spatiotemporal control. It further evaluates applications in targeted drug delivery, gene modulation, and immunotherapy, finally offering perspectives on overcoming translational barriers for clinical ...
Xueyao Wang   +5 more
wiley   +1 more source

AIEgens: An Exemplary Template for “One‐for‐All” Multimodal Phototheranostics

open access: yesAggregate, Volume 7, Issue 4, April 2026.
This review establishes a consensus that AIEgens serve as a quintessential template for “one‐for‐all” multimodal phototheranostics and systematically articulates the underlying rationale from a photophysical perspective. It comprehensively examines corresponding molecular engineering principles and performance optimization tactics, framed within the ...
Miaomiao Kang   +9 more
wiley   +1 more source

Developing HMME‐Conjugated NIR‐II Activated Carbon Dots Nanospray for the Treatment of MRSA Biofilm Infections in Diabetic Wound via PTT/CDT/SDT

open access: yesRare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT Diabetic wound infections are a common complication of diabetes, which severely impact patients' quality of life. Effective treatment of diabetic wound infections remains one major challenge in the clinic, partially due to the formation of bacterial biofilm and antibiotic resistance.
Liang Zhou   +8 more
wiley   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

open access: yesSmall, Volume 22, Issue 16, 17 March 2026.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa   +4 more
wiley   +1 more source

Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan   +5 more
wiley   +1 more source

In Vivo Efficacy of Zinc Phthalocyanine Nanocarriers IN Photodynamic Therapy of Cancer

open access: yesAdvanced Therapeutics, Volume 9, Issue 1, January 2026.
Zinc phthalocyanines are photosensitizing agents used in photodynamic therapy. Their incorporation into nanosystems enables their encapsulation, targeting, and functionalization, optimizing their therapeutic activity. The results highlight their therapeutic potential, reinforcing their relevance as an innovative strategy in cancer treatment and as a ...
Adrian Lima Roberto   +4 more
wiley   +1 more source

Implanted Miniature Light Devices for Phototherapeutics

open access: yesAdvanced Therapeutics, Volume 9, Issue 1, January 2026.
Modern phototherapeutics has many attractive features; however, the shallow penetration of light into skin and tissue is an inherent physical limitation that restricts usage to superficial sites of disease. To mitigate this major problem, researchers and clinicians are actively developing miniature implanted light devices that can be implanted within a
Hailey S. Sanders   +5 more
wiley   +1 more source

Flash Photodynamic Therapy – How the Saturation of Photosensitizer Absorption Enables Selective and Deeper Tumor Treatments

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
FLASH‐PDT uses strongly‐absorbing photosensitizers and pulsed lasers to saturate the photosensitizer absorption at ≈1‐cm tissue depths. This allows for the generation of [ROS] above the necrosis threshold level for tumors, while maintaining [ROS] in peritumoral tissues below that threshold, even when the tumor‐to‐peritumoral tissue ratio is as low as 2.
Luis G. Arnaut   +3 more
wiley   +1 more source

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