Results 311 to 320 of about 428,654 (353)

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi   +2 more
wiley   +1 more source

Magnetic Properties of Ferritin at Different Levels of Degradation: Implications for MRI‐Based Iron Quantification in the Brain

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Ferritin's iron core exhibits complex magnetic properties, as suggested by magnetometry and Mössbauer spectroscopy, which remain incompletely understood. In particular, the antiferromagnetic inner core could influence the accuracy of iron quantification using MRI and raise concerns about postmortem validation studies involving degraded
Stefan Ropele   +8 more
wiley   +1 more source

What Role Does the Central Nervous System Play in Refractory LUTS, and What Are the Therapeutic Implications? ICI‐RS 2025

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk   +7 more
wiley   +1 more source

Hemoglobin receptor redundancy in <i>Staphylococcus aureus</i>: molecular flexibility as a determinant of divergent hemophore activity. [PDF]

open access: yesJ Struct Biol X
Buoli Comani V   +11 more
europepmc   +1 more source

Patterns of parenteral nutrition use in the inpatient setting: A retrospective cohort study

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Parenteral nutrition (PN) supports patients unable to absorb sufficient nutrients from their gastrointestinal tracts. Yet, information about the patterns and extent of PN's in‐hospital use is lacking. Data on this topic should provide comparison points for nutrition support teams and hospital administrators examining PN use in their
Marc Romain   +7 more
wiley   +1 more source

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