Myeloid Heme Oxygenase-1 Regulates the Acute Inflammatory Response to Zymosan in the Mouse Air Pouch [PDF]
, 2018 [EN] Heme oxygenase-1 (HO-1) is induced by many stimuli to modulate the activation and function of different cell types during innate immune responses.
Alcaraz Tormo, Mª Jose +3 more
core +3 more sources
Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death
OncoTarget, 2015 The oncogenic RAS-selective lethal small molecule Erastin triggers a unique iron-dependent form of nonapoptotic cell death termed ferroptosis. Ferroptosis is dependent upon the production of intracellular iron-dependent reactive oxygen species (ROS), but
Min‐Young Kwon +3 more
semanticscholar +1 more source
Effects of nanoparticles on murine macrophages [PDF]
, 2010 Metallic nanoparticles are more and more widely used in an increasing number of applications. Consequently, they are more and more present in the environment, and the risk that they may represent for human health must be evaluated.
A van Dorsselaer +11 more
core +4 more sources
Spin-filtering and Disorder Induced Giant Magnetoresistance in Carbon Nanotubes: Ab Initio Calculations [PDF]
, 2011 Nitrogen-doped carbon nanotubes can provide reactive sites on the porphyrin-like defects. It's well known that many porphyrins have transition metal atoms, and we have explored transition metal atoms bonded to those porphyrin-like defects in N-doped carbon nanotubes.
arxiv +1 more source
Tissue-specific expression of ALA synthase-1 and heme oxygenase-1 and their expression in livers of rats chronically exposed to ethanol [PDF]
, 2008 5-Aminolevulinic acid synthase-1 (ALAS1) and heme oxygenase-1 (HO-1) are the rate-controlling enzymes for heme biosynthesis and degradation, respectively.
Bonkovsky, Herbert L. +5 more
core +1 more source
FEBS Open Bio, 2016 Despite advances in our understanding of the oxidative pathways mediated by free hemoglobin (Hb), the precise contribution of its highly reactive redox forms to tissue and organ toxicities remains ambiguous.
Tigist Kassa +3 more
semanticscholar +1 more source
Off-resonant coherent electron transport over three nanometers in multi-heme protein bioelectronic junctions [PDF]
arXiv, 2020 Multi-heme cytochromes (MHC) are fascinating proteins used by bacterial organisms to shuttle electrons within and between their cells. When placed in a solid state electronic junction, they support temperature-independent currents over several nanometers that are three orders of magnitude higher compared to other redox proteins of comparable size.
arxiv
The effects of Bilirubin and Bilirubin-di-taurate on ischemia reperfusion injruy in a rat model of kidney transplantation [PDF]
, 2011 Background: Heme oxygenase-1 (HO-1) is the rate-limiting enzyme in the conversion of heme into biliverdin, carbon monoxide (CO) and free iron. Biliverdin is then subsequently reduced to bilirubin by the enzyme bilverdin reductase.
Thomas, Michael
core
Length Polymorphisms in Heme Oxygenase-1 and AKI after Cardiac Surgery.
Journal of the American Society of Nephrology, 2016 Heme oxygenase-1 (HO-1) catalyzes the degradation of heme, which may be involved in the pathogenesis of AKI. Length polymorphisms in the number of GT dinucleotide repeats in the HO-1 gene (HMOX1) promoter inversely associate with HMOX1 mRNA expression ...
D. Leaf +8 more
semanticscholar +1 more source
The N-end rule pathway is a sensor of heme [PDF]
, 2008 The conjugation of arginine, by arginyl-transferase, to N-terminal aspartate, glutamate or oxidized cysteine is a part of the N-end rule pathway of protein degradation.
A. Varshavsky +21 more
core +2 more sources