Results 261 to 270 of about 146,694 (331)

Is Deuterium Sequestering by Reactive Carbon Atoms an Important Mechanism to Reduce Deuterium Content in Biological Water?

FASEB BioAdvances, Volume 7, Issue 6, June 2025.
Deuterium, a heavy isotope of hydrogen, is universal in nature, but it disrupts the mitochondrial ATPase pumps. One mechanism that biological organisms may use to reduce deuterium levels in the mitochondria is to sequester deuterium bound to carbon atoms in a small set of organic molecules that have a unique configuration to support such trapping ...
Stephanie Seneff, Greg Nigh, Anthony M. Kyriakopoulos   +2 more
wiley   +1 more source

Heme Oxygenase-1 Drives Metaflammation and Insulin Resistance in Mouse and Man

Cell, 2014
A. Jais, E. Einwallner, O. Sharif, O. Sharif, Klaus Gossens, T. Lu, S. Soyal, David Medgyesi, David Medgyesi, D. Neureiter, Jamile Paier-Pourani, Kevin Dalgaard, J. Duvigneau, Josefine Lindroos-Christensen, Thea-Christin Zapf, S. Amann, S. Saluzzo, S. Saluzzo, Florian Jantscher, P. Stiedl, J. Todoric, R. Martins, R. Martins, H. Oberkofler, Simone Müller, C. Hauser-kronberger, L. Kenner, L. Kenner, E. Casanova, Hedwig Sutterlüty-Fall, M. Bilban, K. Miller, A. Kozlov, F. Krempler, S. Knapp, S. Knapp, C. Lumeng, W. Patsch, O. Wagner, J. Pospisilik, H. Esterbauer   +40 more
semanticscholar   +1 more source

Integrated Analysis of Gene Expression, Protein Synthesis, and Epigenetic Modifications in Alcanivorax borkumensis SK2 Under Iron Limitation

Environmental Microbiology Reports, Volume 17, Issue 3, June 2025.
Summarised transcriptomics, methylomics, and proteomics data plotted to circular maps using Circos software. Meanings of circles and histograms on the plots are explained in the figure legend. ABSTRACT This study aimed to understand the genetic and molecular mechanisms enabling Alcanivorax borkumensis SK2, a hydrocarbonoclastic marine bacterium, to ...
Francesco Smedile, Renata Denaro, Francesca Crisafi, Domenico Giosa, Giuseppe D'Auria, Manuel Ferrer, Riccardo Rosselli, Martin S. Staege, Michail M. Yakimov, Laura Giuliano, Oleg N. Reva   +10 more
wiley   +1 more source

Antioxidant genes in cancer and metabolic diseases: Focusing on Nrf2, Sestrin, and heme oxygenase 1. [PDF]

Int J Biol Sci
Shrestha J, Limbu KR, Chhetri RB, Paudel KR, Hansbro PM, Oh YS, Baek DJ, Ki SH, Park EY.   +8 more
europepmc   +1 more source

The Potential Ability of Betulinic Acid to Prevent Experimentally Induced Acute Pancreatitis in Rats

Basic &Clinical Pharmacology &Toxicology, Volume 136, Issue 6, June 2025.
ABSTRACT Acute pancreatitis (AP) is a serious pancreatic inflammatory disease that results in pancreatic enzyme activation and autodegradation. Betulinic acid (BA), a pentacyclic triterpene of natural origin that was isolated from several plants, has anti‐inflammatory, immunomodulatory and antioxidant effects that can help with AP.
Guler Yenice, Seckin Ozkanlar, Ismail Bolat, Serkan Yildirim   +3 more
wiley   +1 more source

Notoginsenoside R1 Attenuates Cisplatin-Induced Ototoxicity by Inducing Heme Oxygenase-1 Expression and Suppressing Oxidative Stress. [PDF]

Int J Mol Sci
Lin YC, Ho YJ, Lin YY, Liao AH, Kuo CY, Chen HK, Chen HC, Wang CH, Shih CP.   +8 more
europepmc   +1 more source

Expression and Actions of Heme Oxygenase in the Renal Medulla of Rats

, 2000
Ai-Ping Zou, Heather Billington, Na Su, Allen W. Cowley   +3 more
openalex   +1 more source

Cardioprotective and Anti‐Hypertensive Effects of Epigallocatechin Gallate: Novel Insights Into Biological Evidence

The Journal of Clinical Hypertension, Volume 27, Issue 6, June 2025.
ABSTRACT Epigallocatechin gallate (EGCG), the major catechin in green tea, is of considerable interest principally due to its proposed antihypertensive and cardioprotective properties. New research shows that EGCG can help relax the circulation of blood vessels, reduce arterial stiffness of arteries, and promote antioxidant activity promotion, which ...
Reza Eshraghi, Ashkan Bahrami, Faraz Tayyar Iravanlou, Mehdi Karimi, Mohammad Saeed Soleimani, Mohammad Hossein Paknahad, Mohammad Yaghoubi, Arman Beheshtirooy, Fatemeh Qasemi Talouki, Javad Shaabanzadeh, Fatemeh Hasani, Alireza Rafi, Mohammad Hossein Pourhanifeh   +12 more
wiley   +1 more source

Omaveloxolone Suppresses Cell Growth and Causes Cell Cycle Arrest by Downregulating CDC20 Expression in Glioblastoma Cells Both In Vitro and In Vivo

Journal of Cellular and Molecular Medicine, Volume 29, Issue 11, June 2025.
ABSTRACT Omaveloxolone is a synthetic oleanane triterpene with considerable antitumor activity. It induces human glioblastoma (GBM) cell death in vitro and in vivo, but the underlying mechanism remains to be determined. In this study, GBM cell lines (GBM8401 and U‐87 MG cells) were exposed to different concentrations of omaveloxolone (0, 600, 800 and ...
Kuan‐Ting Lee, Yi‐Chiang Hsu, Ann‐Shung Lieu, Chih‐Lung Lin, Tai‐Hsin Tsai   +4 more
wiley   +1 more source

Heme-Oxygenase 1 Mediated Activation of Cyp3A11 Protects Against Non-Steroidal Pain Analgesics Induced Acute Liver Damage in Sickle Cell Disease Mice. [PDF]

Cells
Vats R, Ungalara R, Dubey RK, Sundd P, Pradhan-Sundd T.   +4 more
europepmc   +1 more source