New roles for GAPDH, Hsp90, and NO in regulating heme allocation and hemeprotein function in mammals. [PDF]
Biol Chem, 2022 The intracellular trafficking of mitochondrial heme presents a fundamental challenge to animal cells. This article provides some background on heme allocation, discusses some of the concepts, and then reviews research done over the last decade, much in ...
Stuehr DJ +4 more
europepmc +4 more sources
Role of the Circadian Gas-Responsive Hemeprotein NPAS2 in Physiology and Pathology [PDF]
Biology, 2023 Neuronal PAS domain protein 2 (NPAS2) is a hemeprotein comprising a basic helix–loop–helix domain (bHLH) and two heme-binding sites, the PAS-A and PAS-B domains.
Emanuele Murgo +4 more
doaj +3 more sources
Ferruginous hemeprotein HhuH facilitates the cadmium adsorption and chromium reduction in Stenotrophomonas sp. SY1 [PDF]
Applied and Environmental MicrobiologyCadmium (Cd) and chromium (Cr) are frequently encountered toxicants, while iron (Fe) plays a crucial role in bacterial survival under conditions of heavy metal stress.
Zijie Zhou +5 more
doaj +3 more sources
Light‐Induced Pulsed EPR Dipolar Spectroscopy on a Paradigmatic Hemeprotein [PDF]
ChemPhysChem, 2019 AbstractLight‐induced pulsed EPR dipolar spectroscopic methods allow the determination of nanometer distances between paramagnetic sites. Here we employ orthogonal spin labels, a chromophore triplet state and a stable radical, to carry out distance measurements in singly nitroxide‐labeled human neuroglobin.
Dal Farra, Maria Giulia +8 more
semanticscholar +7 more sources
Open Chemistry, 2020 A unique method was used to synthesize extremely stable silver stearate nanoparticles (AgStNPs) incorporated in an organic-based monolith. The facile strategy was then used to selectively isolate hemeproteins, myoglobin (Myo)
Alzahrani Eman
doaj +3 more sources
PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ [PDF]
Computational and Structural Biotechnology Journal, 2022 Intrinsic protein flexibility is of overwhelming relevance for intermolecular recognition and adaptability of highly dynamic ensemble of complexes, and the phenomenon is essential for the understanding of numerous biological processes.
Miguel Á. Casado-Combreras +12 more
doaj +9 more sources
Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c [PDF]
Redox Biology, 2021 Repair of injured DNA relies on nucleosome dismantling by histone chaperones and de-phosphorylation events carried out by Protein Phosphatase 2A (PP2A).
Francisco Rivero-Rodríguez +8 more
doaj +5 more sources
Bio-Electroanalysis Performance of Heme Redox-Center for π-π Interaction Bonding of a Methylene Blue-Graphene Modified Electrode [PDF]
Nanomaterials, 2023 Hemeprotein detection has motivated extensive research on the direct reaction of a heme molecule and a redox dye. The present study used methylene blue as both donor and acceptor for a redox reaction.
Porntip Khownarumit +5 more
doaj +2 more sources
Femtosecond imaging of giant-hemeprotein with XFEL pulses
Biophysical Journal, 2023 Published by Biophysical Soc., Bethesda, Md.
Lourdu Xavier, Paulraj +14 more
openaire +3 more sources
Hsp90 in Human Diseases: Molecular Mechanisms to Therapeutic Approaches [PDF]
Cells, 2022 The maturation of hemeprotein dictates that they incorporate heme and become active, but knowledge of this essential cellular process remains incomplete. Studies on chaperon Hsp90 has revealed that it drives functional heme maturation of inducible nitric
Mamta P. Sumi, Arnab Ghosh
doaj +2 more sources