Role of the Circadian Gas-Responsive Hemeprotein NPAS2 in Physiology and Pathology [PDF]
Neuronal PAS domain protein 2 (NPAS2) is a hemeprotein comprising a basic helix–loop–helix domain (bHLH) and two heme-binding sites, the PAS-A and PAS-B domains.
Emanuele Murgo+4 more
doaj +7 more sources
Finding Value in Wastewaters from the Cork Industry: Carbon Dots Synthesis and Fluorescence for Hemeprotein Detection [PDF]
Valorisation of industrial low-value waste residues was preconized. Hence, carbon dots (C-dots) were synthesized from wastewaters of the cork industry—an abundant and affordable, but environmentally-problematic industrial effluent.
Marta R. Alexandre+3 more
doaj +3 more sources
Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c [PDF]
Repair of injured DNA relies on nucleosome dismantling by histone chaperones and de-phosphorylation events carried out by Protein Phosphatase 2A (PP2A).
Francisco Rivero-Rodríguez+8 more
doaj +5 more sources
Spectral Studies of Iron Coordination in Hemeprotein Complexes Difference Spectroscopy below 250 mμ [PDF]
In order to evaluate the feasibility of observing the spectral behavior of protein groups in the coordination sphere of the iron in hemeproteins, criteria are developed to determine whether or not the application of difference absorption spectroscopy to ...
Brill, Arthur S., Sandberg, Howard E.
core +3 more sources
New roles for GAPDH, Hsp90, and NO in regulating heme allocation and hemeprotein function in mammals. [PDF]
The intracellular trafficking of mitochondrial heme presents a fundamental challenge to animal cells. This article provides some background on heme allocation, discusses some of the concepts, and then reviews research done over the last decade, much in ...
Stuehr DJ+4 more
europepmc +2 more sources
Bio-Electroanalysis Performance of Heme Redox-Center for π-π Interaction Bonding of a Methylene Blue-Graphene Modified Electrode [PDF]
Hemeprotein detection has motivated extensive research on the direct reaction of a heme molecule and a redox dye. The present study used methylene blue as both donor and acceptor for a redox reaction.
Porntip Khownarumit+5 more
doaj +2 more sources
Hsp90 in Human Diseases: Molecular Mechanisms to Therapeutic Approaches [PDF]
The maturation of hemeprotein dictates that they incorporate heme and become active, but knowledge of this essential cellular process remains incomplete. Studies on chaperon Hsp90 has revealed that it drives functional heme maturation of inducible nitric
Mamta P. Sumi, Arnab Ghosh
doaj +2 more sources
Ferruginous hemeprotein HhuH facilitates the cadmium adsorption and chromium reduction in <i>Stenotrophomonas</i> sp. SY1. [PDF]
Cadmium (Cd) and chromium (Cr) are frequently encountered toxicants, while iron (Fe) plays a crucial role in bacterial survival under conditions of heavy metal stress.
Zhou Z+5 more
europepmc +2 more sources
Behind the Optimization of the Sensor Film: Bioconjugation of Triangular Gold Nanoparticles with Hemoproteins for Sensitivity Enhancement of Enzymatic Biosensors [PDF]
Electrochemical biosensors are widely used in a multitude of applications, such as medical, nutrition, research, among other fields. These sensors have been historically used and have not undergone many changes in terms of the involved electrochemical ...
Miriam Chávez+6 more
doaj +2 more sources
PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ. [PDF]
Intrinsic protein flexibility is of overwhelming relevance for intermolecular recognition and adaptability of highly dynamic ensemble of complexes, and the phenomenon is essential for the understanding of numerous biological processes.
Casado-Combreras MÁ+12 more
europepmc +7 more sources