Evolutionary Pro-To-Thr Mutation in the Intrinsically Disordered Domain of ANP32 Family Members Modulates Their Target Binding Modes. [PDF]
Adv Sci (Weinh)Gene duplication has allowed protein evolution toward novel functions and mechanisms. The differences between paralogous genes frequently rely on the sequence of disordered regions.
Baños-Jaime B +8 more
europepmc +4 more sources
Femtosecond imaging of giant-hemeprotein with XFEL pulses.
Biophysical Journal, 2023 Published by Biophysical Soc., Bethesda, Md.
P. Lourdu Xavier +14 more
semanticscholar +4 more sources
Low levels of nitric oxide promotes heme maturation into several hemeproteins and is also therapeutic [PDF]
Redox Biology, 2022 Nitric oxide (NO) is a signal molecule and plays a critical role in the regulation of vascular tone, displays anti-platelet and anti-inflammatory properties.
Arnab Ghosh +8 more
doaj +2 more sources
Open Chemistry, 2020 A unique method was used to synthesize extremely stable silver stearate nanoparticles (AgStNPs) incorporated in an organic-based monolith. The facile strategy was then used to selectively isolate hemeproteins, myoglobin (Myo)
Alzahrani Eman
doaj +2 more sources
Assimilatory Nitrate Reductase of Rhodopseudomonas capsulata AD2: A Molybdo-Hemeprotein [PDF]
Zeitschrift fur Naturforschung. Section C, Biosciences, 1979 The assimilatory nitrate reductase of the phototrophic bacterium Rhodopseudomonas capsulata strain AD2 was purified to homogeneity by a combination of ammonium sulfate fractionation, chromatography on DEAE-cellulose and isoelectric focusing (isoelectric ...
Kasem Alef, J. Klemme
semanticscholar +2 more sources
Site-directed Mutagenesis of Cytochromec 6 from Anabaena Species PCC 7119 [PDF]
Journal of Biological Chemistry, 1999 A number of surface residues of cytochromec 6 from the cyanobacterium Anabaenasp. PCC 7119 have been modified by site-directed mutagenesis. Changes were made in six amino acids, two near the heme group (Val-25 and Lys-29) and four in the positively ...
Díaz Quintana, Antonio Jesús +4 more
core +2 more sources
Regulation of the expression of ferrochelatase in a murine model of diabetes mellitus type I [PDF]
Biochemistry and Biophysics ReportsBackground: Diabetes produces changes on cellular hemeprotein metabolism. The last enzyme of heme biosynthetic pathway is ferrochelatase (FECH), an enzyme that catalyzes the insertion of ferrous ion into protoporphyrin IX to produce heme. The aim of this
Leda María Oliveri +2 more
doaj +2 more sources
Neuroglobin regulates autophagy through mTORC1/RAPTOR/ULK-1 pathway in human neuroblastoma cells [PDF]
Scientific ReportsNeuroglobin (NGB) is a hexacoordinated hemeprotein mainly expressed in neurons. Following its upregulation and mitochondrial localization, NGB plays a pro-survival role against neuronal stress.
Valeria Manganelli +12 more
doaj +2 more sources
A microscale isolation of hemins from hemeproteins by use of polyacrylamide gel electrophoresis [PDF]
, 1975 An analytical and semipreparative procedure has been developed for the isolation of the prosthetic groups of various hemeproteins by use of polyacrylamide gel electrophoresis.
Anson +19 more
core +2 more sources
Light‐Induced Pulsed EPR Dipolar Spectroscopy on a Paradigmatic Hemeprotein
ChemPhysChem, 2019 Light‐induced pulsed EPR dipolar spectroscopic methods allow the determination of nanometer distances between paramagnetic sites. Here we employ orthogonal spin labels, a chromophore triplet state and a stable radical, to carry out distance measurements ...
Maria Giulia Dal Farra +8 more
semanticscholar +6 more sources