Results 31 to 40 of about 1,942 (200)

The Effect of 5-Aminolevulinic Acid on Cytochrome P450-Mediated Prodrug Activation. [PDF]

open access: yesPLoS ONE, 2015
Of late, numerous prodrugs are widely used for therapy. The hemeprotein cytochrome P450 (CYP) catalyzes the activation of prodrugs to form active metabolites.
Mai Miura   +5 more
doaj   +1 more source

Tracking Heme-Protein Interactions in Healthy and Pathological Human Serum in Native Conditions by Miniaturized FFF-Multidetection

open access: yesApplied Sciences, 2022
The interaction of heme with blood serum proteins plays an important role in many physiological and pathological processes involving enzyme activity, gene expression and cell proliferation.
Valentina Marassi   +4 more
doaj   +1 more source

Theoretical Study on the Effective Magnetic Moments of Some Hemeproteins [PDF]

open access: bronzeProgress of Theoretical Physics Supplement, 1961
It is pointed out that the measurement of the static magnetic susceptibilities over a wide temperature range will be able to the detailed information about the electronic structure of the paramagnetic heme derivatives. On the basis of the data given by the electron paramagnetic resonance experiment, formulas for the temperature dependence of the ...
Masao Kotani
openalex   +3 more sources

Rhabdomyolysis as cause, consequence, or mimicker of myocardial infarction: A case report

open access: yesClinical Case Reports, Volume 11, Issue 11, November 2023., 2023
Key Clinical Message A timely diagnosis is essential to start appropriate therapy and to reduce risks of life‐threatening complications of rhabdomyolysis. Some cases can undergo differential diagnosis with other clinical conditions, e.g., myocardial infarction.
Marina Nasello   +11 more
wiley   +1 more source

The Histone Chaperones SET/TAF‐1β and NPM1 Exhibit Conserved Functionality in Nucleosome Remodeling and Histone Eviction in a Cytochrome c‐Dependent Manner

open access: yesAdvanced Science, Volume 10, Issue 29, October 17, 2023., 2023
This study focuses on the molecular action of two histone chaperones: SET/template‐activating factor‐Iβ and nucleophosmin 1. It is shown how these chaperones have specificity for fully dismantled nucleosomes, characterized the histone eviction (removal) process, and its modulation by cytochrome c.
Pedro Buzón   +5 more
wiley   +1 more source

The Reactions of Antibodies with Hemeprotein Antigens

open access: hybrid, 1969
Robert W. Noble   +2 more
openalex   +2 more sources

CYP116B5hd, a self-sufficient P450 cytochrome: A dataset of its electronic and geometrical properties

open access: yesData in Brief, 2022
This paper documents the dataset obtained from the Electron Paramagnetic Resonance (EPR) study of the electronic properties of a self-sufficient cytochrome P450, CYP116B5hd, which possesses an interesting catalytic activity for synthetic purposes.
Antonino Famulari   +5 more
doaj   +1 more source

Site-selective protein modification via disulfide rebridging for fast tetrazine/trans-cyclooctene bioconjugation [PDF]

open access: yes, 2020
An inverse electron demand Diels–Alder reaction between tetrazine and trans-cyclooctene (TCO) holds great promise for protein modification and manipulation.
Chudasama, V.   +6 more
core   +1 more source

Hemeprotein Tpx1 interacts with cell‐surface heme transporter Str3 in Schizosaccharomyces pombe

open access: yesMolecular Microbiology, 2020
Str3 is a transmembrane protein that mediates low‐affinity heme uptake in Schizosaccharomyces pombe. Under iron‐limiting conditions, Str3 remains at the cell surface in the presence of increasing hemin concentrations.
Vincent Normant   +6 more
semanticscholar   +1 more source

A natural heme deficiency exists in biology that allows nitric oxide to control heme protein functions by regulating cellular heme distribution

open access: yesBioEssays, Volume 45, Issue 8, August 2023., 2023
We hypothesize that tissues exist naturally in a heme‐deficient condition that limits the heme content and functions of heme proteins. The nitric oxide (NO) that is made in our tissues can control cell heme availability in a bimodal way, and so regulate heme protein functions in health and disease.
Dennis J. Stuehr   +5 more
wiley   +1 more source

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