Results 31 to 40 of about 1,725 (195)

Recombinant Hemoglobin II From Lucina pectinata: A Large-Scale Method For Hemeprotein Expression in E. coli

open access: greenThe Protein Journal, 2010
C. Ramos   +6 more
semanticscholar   +3 more sources

Reversing the Enantioselectivity of Enzymatic Carbene N−H Insertion Through Mechanism‐Guided Protein Engineering**

open access: yesAngewandte Chemie, Volume 135, Issue 35, August 28, 2023., 2023
Computational modelling was employed to rationally guide protein engineering toward controlling the accessible conformations of a key lactone‐carbene (LAC) intermediate in the enzyme active site by installing a new H‐bond anchoring point. This H‐bonding interaction controls the relative orientation of the fleeting carbene intermediate, orienting it for
Carla Calvó‐Tusell   +4 more
wiley   +2 more sources

Tracking Heme-Protein Interactions in Healthy and Pathological Human Serum in Native Conditions by Miniaturized FFF-Multidetection

open access: yesApplied Sciences, 2022
The interaction of heme with blood serum proteins plays an important role in many physiological and pathological processes involving enzyme activity, gene expression and cell proliferation.
Valentina Marassi   +4 more
doaj   +1 more source

The Effect of 5-Aminolevulinic Acid on Cytochrome P450-Mediated Prodrug Activation. [PDF]

open access: yesPLoS ONE, 2015
Of late, numerous prodrugs are widely used for therapy. The hemeprotein cytochrome P450 (CYP) catalyzes the activation of prodrugs to form active metabolites.
Mai Miura   +5 more
doaj   +1 more source

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