Results 41 to 50 of about 1,725 (195)

Hyperspectral Absorption Microscopy Using Photoacoustic Remote Sensing [PDF]

, 2021
An improved method of remote optical absorption spectroscopy and hyperspectral optical absorption imaging is described which takes advantage of the photoacoustic remote sensing detection architecture. A wide range of photoacoustic excitation wavelengths ranging from 210 nm to 1550 nm was provided by a nanosecond tunable source allowing access to ...
arxiv   +1 more source

A natural heme deficiency exists in biology that allows nitric oxide to control heme protein functions by regulating cellular heme distribution

BioEssays, Volume 45, Issue 8, August 2023., 2023
We hypothesize that tissues exist naturally in a heme‐deficient condition that limits the heme content and functions of heme proteins. The nitric oxide (NO) that is made in our tissues can control cell heme availability in a bimodal way, and so regulate heme protein functions in health and disease.
Dennis J. Stuehr, Pranjal Biswas, Yue Dai, Arnab Ghosh, Sidra Islam, Dhanya Thamaraparambil Jayaram   +5 more
wiley   +1 more source

Hemeprotein Tpx1 interacts with cell‐surface heme transporter Str3 in Schizosaccharomyces pombe

Molecular Microbiology, 2020
Str3 is a transmembrane protein that mediates low‐affinity heme uptake in Schizosaccharomyces pombe. Under iron‐limiting conditions, Str3 remains at the cell surface in the presence of increasing hemin concentrations.
Vincent Normant, Ariane Brault, M. Avino, Thierry Mourer, Tobias Vahsen, J. Beaudoin, S. Labbé   +6 more
semanticscholar   +1 more source

Critical role for uricase and xanthine dehydrogenase in soybean nitrogen fixation and nodule development

The Plant Genome, Volume 16, Issue 2, June 2023., 2023
Abstract De novo purine biosynthesis is required for the incorporation of fixed nitrogen in ureide exporting nodules, as formed on soybean [Glycine max (L.) Merr.] roots. However, in many cases, the enzymes involved in this pathway have been deduced strictly from genome annotations with little direct genetic evidence, such as mutant studies, to confirm
Cuong X. Nguyen, Alice Dohnalkova, C. Nathan Hancock, Kendall R. Kirk, Gary Stacey, Minviluz G. Stacey   +5 more
wiley   +1 more source

Design of Artificial Enzymes: Insights into Protein Scaffolds

ChemBioChem, Volume 24, Issue 6, March 14, 2023., 2023
The design of artificial enzymes has emerged as a promising tool for the generation of potent biocatalysts able to promote new‐to‐nature reactions. This review aims to give a general overview of suitable protein scaffolds, that could be functionalized with an artificial moiety to develop versatile artificial catalysts. Abstract The design of artificial
Stefanie Hanreich, Elisa Bonandi, Ivana Drienovská   +2 more
wiley   +1 more source

Endothelial Glycocalyx Injury in SARS‐CoV‐2 Infection: Molecular Mechanisms and Potential Targeted Therapy

Mediators of Inflammation, Volume 2023, Issue 1, 2023., 2023
This review aims at summarizing state‐of‐the‐art knowledge on glycocalyx and SARS‐CoV‐2. The endothelial glycocalyx is a dynamic grid overlying the surface of the endothelial cell (EC) lumen and consists of membrane‐bound proteoglycans and glycoproteins.
Bingxuan Lv, Shengshi Huang, Hong Huang, Na Niu, Ju Liu, Mohammad Shadab   +5 more
wiley   +1 more source

Insights into Sulfhemoglobin Detection: UV‐Vis and Fluorescence Spectroscopy Correlations

Journal of Chemistry, Volume 2023, Issue 1, 2023., 2023
The mechanisms by which drugs and several sulfur chemicals induce sulfhemoglobin formation have not yet been elucidated. However, enzymes producing hydrogen sulfide in mammalian tissues and organs suggest sulfhemoglobin and sulfmyoglobin formation mechanisms are more complex than previously hypothesized. The process involves the interaction of H2S with
Lysmarie Santos-Velázquez, Juan López-Garriga, Mohd Sajid Ali   +2 more
wiley   +1 more source

Factors Controlling the Reactivity of Hydrogen Sulfide with Hemeproteins [PDF]

Biochemistry, 2009
Hemoglobin I (HbI) from the clam Lucina pectinata is an intriguing hemeprotein that binds and transports H(2)S to sulfide-oxidizing chemoautotrophic bacteria to maintain a symbiotic relationship and to protect the mollusk from H(2)S toxicity. Single point mutations at E7, B10, and E11 were introduced into the HbI heme pocket to define the reactivity of
Sebastian Fernandez-Alberti, Laurent Kiger, Ariel Lewis, Juan López-Garriga, Michael C. Marden, Syun Ru Yeh, Carmen L. Cadilla, Ruth G. León, Gullermina Casabona, Ruth Pietri   +9 more
openaire   +2 more sources

α‐Dioxygenases (α‐DOXs): Promising Biocatalysts for the Environmentally Friendly Production of Aroma Compounds

ChemBioChem, Volume 23, Issue 12, June 20, 2022., 2022
α‐Dioxygenases (α‐DOXs) are promising biocatalysts that catalyze the oxidation of fatty acids to produce (one carbon‐shortened) fatty aldehydes, which are used as flavors and fragrances. This comprehensive review summarizes the recent advances in the biotechnological utilization of α‐DOXs with focus on newly discovered cyanobacterial α‐DOXs together ...
In Jung Kim, Thomas Bayer, Henrik Terholsen, Uwe T. Bornscheuer   +3 more
wiley   +1 more source

Cytoglobin attenuates pancreatic cancer growth via scavenging reactive oxygen species

Oncogenesis, 2022
Pancreatic cancer is a highly challenging malignancy with extremely poor prognosis. Cytoglobin (CYGB), a hemeprotein involved in liver fibrosis and cancer development, is expressed in pericytes of all organs.
Dinh Viet Hoang, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Kenjiro Kimura, Daisuke Oikawa, Yoshihiro Ikura, Ninh Quoc Dat, Truong Huu Hoang, Misako Sato-Matsubara, Minh Phuong Dong, Ngo Vinh Hanh, Sawako Uchida-Kobayashi, Fuminori Tokunaga, Shoji Kubo, Naoko Ohtani, Katsutoshi Yoshizato, Norifumi Kawada   +17 more
doaj   +1 more source