Demonstration that spleen green hemeprotein is identical to granulocyte myeloperoxidase.
The biochemical, spectroscopic, enzymatic, and redox properties of spleen myeloperoxidase, a peroxidase formerly called "spleen green hemeprotein," and granulocyte myeloperoxidase were compared by electrophoresis, amino-terminal amino acid sequences, optical and EPR spectroscopy, steady-state enzyme kinetics, and oxidation-reduction potential.
M. Ikeda-Saito+7 more
semanticscholar +4 more sources
Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation at tyrosine 48 [PDF]
Regulation of mitochondrial activity allows cells to adapt to changing conditions and to control oxidative stress, and its dysfunction can lead to hypoxia-dependent pathologies such as ischemia and cancer.
Conte, Rebecca del+7 more
core +4 more sources
Nitric oxide (NO) is a signal molecule and plays a critical role in the regulation of vascular tone, displays anti-platelet and anti-inflammatory properties.
Arnab Ghosh+8 more
doaj +1 more source
Hemoglobin I from Lucina pectinata on Collagen Scaffold: A Prospective Hydrogen Sulfide Scavenger
Hydrogen sulfide (H2S), independently of being a toxic gas with a characteristic smell of rotten eggs, is a crucial signaling molecule with significant physiological functions.
Jennifer Vargas Santiago+2 more
doaj +1 more source
THE DETERMINATION OF ELECTRONIC PROPERTIES BY PROTEIN STRUCTURE IN HEMEPROTEIN
Rufus Lumry
openalex +4 more sources
Cytoglobin attenuates pancreatic cancer growth via scavenging reactive oxygen species
Pancreatic cancer is a highly challenging malignancy with extremely poor prognosis. Cytoglobin (CYGB), a hemeprotein involved in liver fibrosis and cancer development, is expressed in pericytes of all organs.
Dinh Viet Hoang+17 more
doaj +1 more source
Myoglobin is a hemeprotein that reversibly binds oxygen and gives muscle its red color. Here, the authors report a genetic variant in the MB gene that associates with myoglobinopathy, an autosomal dominant progressive myopathy, and altered oxygen binding
Montse Olivé+43 more
doaj +1 more source
Resonance Raman Spectroscopy of the Oxygenated Intermediates of Human CYP19A1 Implicates a Compound I Intermediate in the Final Lyase Step [PDF]
CYP19A1, or aromatase, a cytochrome P450 responsible for estrogen biosynthesis in humans, is an important therapeutic target for the treatment of breast cancer.
Kincaid, James R.+3 more
core +2 more sources
Optimization of Hnox Protein Production in Escherichia Coli
Hemeproteinscarry a variety of different functions in organisms ranging from steroidbiosynthesis to respiration, signaling to drug metabolism. In industry,hemeproteins are used for production of drugs such as: pravastatin for loweringcholesterol ...
Nur Başak Sürmeli
doaj +1 more source
Cloning, Expression, and Purification of a Nitric Oxide Synthase-Like Protein from Bacillus cereus
The nitric oxide synthase-like protein from Bacillus cereus (bcNOS) has been cloned, expressed, and characterized. This small hemeprotein (356 amino acids in length) has a mass of 43 kDa and forms a dimer.
Heather J. Montgomery+3 more
doaj +1 more source