Results 51 to 60 of about 1,942 (200)

Demonstration that spleen green hemeprotein is identical to granulocyte myeloperoxidase.

open access: yesJournal of Biological Chemistry, 1989
The biochemical, spectroscopic, enzymatic, and redox properties of spleen myeloperoxidase, a peroxidase formerly called "spleen green hemeprotein," and granulocyte myeloperoxidase were compared by electrophoresis, amino-terminal amino acid sequences, optical and EPR spectroscopy, steady-state enzyme kinetics, and oxidation-reduction potential.
M. Ikeda-Saito   +7 more
semanticscholar   +4 more sources

Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation at tyrosine 48 [PDF]

open access: yes, 2017
Regulation of mitochondrial activity allows cells to adapt to changing conditions and to control oxidative stress, and its dysfunction can lead to hypoxia-dependent pathologies such as ischemia and cancer.
Conte, Rebecca del   +7 more
core   +4 more sources

Low levels of nitric oxide promotes heme maturation into several hemeproteins and is also therapeutic

open access: yesRedox Biology, 2022
Nitric oxide (NO) is a signal molecule and plays a critical role in the regulation of vascular tone, displays anti-platelet and anti-inflammatory properties.
Arnab Ghosh   +8 more
doaj   +1 more source

Hemoglobin I from Lucina pectinata on Collagen Scaffold: A Prospective Hydrogen Sulfide Scavenger

open access: yesJournal of Chemistry, 2022
Hydrogen sulfide (H2S), independently of being a toxic gas with a characteristic smell of rotten eggs, is a crucial signaling molecule with significant physiological functions.
Jennifer Vargas Santiago   +2 more
doaj   +1 more source

Cytoglobin attenuates pancreatic cancer growth via scavenging reactive oxygen species

open access: yesOncogenesis, 2022
Pancreatic cancer is a highly challenging malignancy with extremely poor prognosis. Cytoglobin (CYGB), a hemeprotein involved in liver fibrosis and cancer development, is expressed in pericytes of all organs.
Dinh Viet Hoang   +17 more
doaj   +1 more source

Myoglobinopathy is an adult-onset autosomal dominant myopathy with characteristic sarcoplasmic inclusions

open access: yesNature Communications, 2019
Myoglobin is a hemeprotein that reversibly binds oxygen and gives muscle its red color. Here, the authors report a genetic variant in the MB gene that associates with myoglobinopathy, an autosomal dominant progressive myopathy, and altered oxygen binding
Montse Olivé   +43 more
doaj   +1 more source

Resonance Raman Spectroscopy of the Oxygenated Intermediates of Human CYP19A1 Implicates a Compound I Intermediate in the Final Lyase Step [PDF]

open access: yes, 2014
CYP19A1, or aromatase, a cytochrome P450 responsible for estrogen biosynthesis in humans, is an important therapeutic target for the treatment of breast cancer.
Kincaid, James R.   +3 more
core   +2 more sources

Optimization of Hnox Protein Production in Escherichia Coli

open access: yesCumhuriyet Science Journal, 2017
Hemeproteinscarry a variety of different functions in organisms ranging from steroidbiosynthesis to respiration, signaling to drug metabolism. In industry,hemeproteins are used for production of drugs such as: pravastatin for loweringcholesterol ...
Nur Başak Sürmeli
doaj   +1 more source

Cloning, Expression, and Purification of a Nitric Oxide Synthase-Like Protein from Bacillus cereus

open access: yesBiochemistry Research International, 2010
The nitric oxide synthase-like protein from Bacillus cereus (bcNOS) has been cloned, expressed, and characterized. This small hemeprotein (356 amino acids in length) has a mass of 43 kDa and forms a dimer.
Heather J. Montgomery   +3 more
doaj   +1 more source

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