Mediators of Inflammation, Volume 2023, Issue 1, 2023., 2023 This review aims at summarizing state‐of‐the‐art knowledge on glycocalyx and SARS‐CoV‐2. The endothelial glycocalyx is a dynamic grid overlying the surface of the endothelial cell (EC) lumen and consists of membrane‐bound proteoglycans and glycoproteins.
Bingxuan Lv +5 more
wiley +1 more source
Inhibitory domain-specific antibodies to cytochrome P-450scc [PDF]
, 1989 Highly specific antibodies to cytochrome P-450scc and its F1 and F2 fragments, representing N- and C-terminal sequences of the hemeprotein respectively, were raised in rabbits.
Chashchin, Vadim L. +2 more
core +1 more source
Factors Controlling the Reactivity of Hydrogen Sulfide with Hemeproteins [PDF]
Biochemistry, 2009 Hemoglobin I (HbI) from the clam Lucina pectinata is an intriguing hemeprotein that binds and transports H(2)S to sulfide-oxidizing chemoautotrophic bacteria to maintain a symbiotic relationship and to protect the mollusk from H(2)S toxicity. Single point mutations at E7, B10, and E11 were introduced into the HbI heme pocket to define the reactivity of
Sebastian Fernandez-Alberti +9 more
openaire +2 more sources
Insights into Sulfhemoglobin Detection: UV‐Vis and Fluorescence Spectroscopy Correlations
Journal of Chemistry, Volume 2023, Issue 1, 2023., 2023 The mechanisms by which drugs and several sulfur chemicals induce sulfhemoglobin formation have not yet been elucidated. However, enzymes producing hydrogen sulfide in mammalian tissues and organs suggest sulfhemoglobin and sulfmyoglobin formation mechanisms are more complex than previously hypothesized. The process involves the interaction of H2S with
Lysmarie Santos-Velázquez +2 more
wiley +1 more source
Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation at tyrosine 48 [PDF]
, 2017 Regulation of mitochondrial activity allows cells to adapt to changing conditions and to control oxidative stress, and its dysfunction can lead to hypoxia-dependent pathologies such as ischemia and cancer.
Conte, Rebecca del +7 more
core +4 more sources
Cytochrome c: Surfing Off of the Mitochondrial Membrane on the Tops of Complexes III and IV [PDF]
, 2019 The proper arrangement of protein components within the respiratory electron transport chain is nowadays a matter of intense debate, since altering it leads to cell aging and other related pathologies.
Díaz Moreno, Irene +4 more
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Hemoglobin I from Lucina pectinata on Collagen Scaffold: A Prospective Hydrogen Sulfide Scavenger
Journal of Chemistry, 2022 Hydrogen sulfide (H2S), independently of being a toxic gas with a characteristic smell of rotten eggs, is a crucial signaling molecule with significant physiological functions.
Jennifer Vargas Santiago +2 more
doaj +1 more source
Label-free photoacoustic microscopy of cytochromes [PDF]
, 2013 Photoacoustic microscopy (PAM) has achieved submicron lateral resolution in showing subcellular structures; however, relatively few endogenous subcellular contrasts have so far been imaged. Given that the hemeprotein, mostly cytochromes in general cells,
Wang, Lihong V. +4 more
core +1 more source
Cytoglobin attenuates pancreatic cancer growth via scavenging reactive oxygen species
Oncogenesis, 2022 Pancreatic cancer is a highly challenging malignancy with extremely poor prognosis. Cytoglobin (CYGB), a hemeprotein involved in liver fibrosis and cancer development, is expressed in pericytes of all organs.
Dinh Viet Hoang +17 more
doaj +1 more source
Site-selective protein modification via disulfide rebridging for fast tetrazine/trans-cyclooctene bioconjugation [PDF]
, 2020 An inverse electron demand Diels–Alder reaction between tetrazine and trans-cyclooctene (TCO) holds great promise for protein modification and manipulation.
Chudasama, V. +6 more
core +1 more source