Results 61 to 70 of about 1,942 (200)

Myeloperoxidase can differentiate between sepsis and non-infectious SIRS and predicts mortality in intensive care patients with SIRS

Intensive Care Medicine Experimental, 2017
Background Systemic inflammatory response syndrome (SIRS) is a clinical syndrome following inflammation. Clinically, it is difficult to distinguish SIRS following an infection, i.e., sepsis, from non-infectious SIRS.
Irene T. Schrijver, Hans Kemperman, Mark Roest, Jozef Kesecioglu, Dylan W. de Lange   +4 more
doaj   +1 more source

Evaluation of hemolysis effect on hemoglobin measurement by capillary electrophoresis

Journal of Analytical Science and Technology, 2019
Background Hemoglobin (Hb) is a hemeprotein with two linked pairs of globin chains. Each chain is connected to a heme residue in its center. Hemoglobinopathies are divided into quantitative and qualitative defects in globin synthesis.
Armin Mokhtariye, Abdol-Reza Varasteh, Amin Alaei, Sima Marzban, Fatemeh Keyfi   +4 more
doaj   +1 more source

Assessment of biochemical parameters and study its correlation in ß-Thalassemia major patients and healthy controls in Kirkuk City, Iraq

Medical Journal of Babylon, 2020
Background: Thalassemia is the name of a group of genetically (acquired) blood diseases, which include defects on the production of hemeprotein, and fractional or complete damage to the combination of a particular sort of simple protein chain. The defect
Ismail Khalil Abd, Israa Ghassan Zainal
doaj   +1 more source

Effect of crowding on the electron transfer process from plastocyanin and cytochrome c6 to photosystem I: a comparative study from cyanobacteria to green algae [PDF]

, 2011
Plastocyanin and cytochrome c 6, the alternate donor proteins to photosystem I, can be acidic, neutral or basic; the role of electrostatics in their interaction with photosystem I vary accordingly for cyanobacteria, algae and plants.
Hervás Morón, Manuel, Navarro Carruesco, José Antonio   +1 more
core   +1 more source

Ferricytochrome c Directly Oxidizes Aminoacetone to Methylglyoxal, a Catabolite Accumulated in Carbonyl Stress [PDF]

, 2013
Age-related diseases are associated with increased production of reactive oxygen and carbonyl species such as methylglyoxal. Aminoacetone, a putative threonine catabolite, is reportedly known to undergo metal-catalyzed oxidation to methylglyoxal, NH4 ...
Bechara, Etelvino José Henriques, Dyszy, Fabio H., Mano, Camila M., Mantovani, Mariana C., Massari, Julio, Nantes, Iseli L., Nascimento, Otaciro R., Sartori, Adriano, Tokikawa, Rita   +8 more
core   +2 more sources

Heme and iron limitation in a GI-tract foundation species leads to a reshuffling of the metalloproteome and a shift toward manganese usage

Frontiers in Chemistry
The metal-binding complement of the cellular proteome (the metalloproteome) depends on metal availability in the cellular environment and drives cellular metabolism.
Ronivaldo Rodrigues da Silva, James Larson, Brian Bothner, Jennifer L. DuBois   +3 more
doaj   +1 more source

Rotenone selectively occludes sensitivity to hypoxia in rat carotid body glomus cells [PDF]

, 2003
Carotid body glomus cells release transmitters in response to hypoxia due to the increase of excitability resulting from inhibition of O2 -regulated K+ channels. However, the mechanisms involved in the detection of changes of O2 tension are unknown.
García Fernández, María, López Barneo, José, Ortega Sáenz, Patricia, Pardal Redondo, Ricardo   +3 more
core   +2 more sources

Conformational Dependence of a Protein Kinase Phosphate Transfer Reaction

, 2004
Atomic motions and energetics for a phosphate transfer reaction catalyzed by the cAMP-dependent protein kinase (PKA) are calculated by plane-wave density functional theory, starting from structures of proteins crystallized in both the reactant ...
Austin, B. H. McMahon, C.-S. Tung, Cheng, Clementi, Frauenfelder, Frauenfelder, G. Henkelman, Hanggi, Johnson, Johnson, M. X. LaBute, Madhusudan, McMahon, N  meth, P. W. Fenimore, Pearson, Pinna, Smith, Songyang, Valiev, Yang, Zheng   +22 more
core   +2 more sources

BioSuper: A web tool for the superimposition of biomolecules and assemblies with rotational symmetry [PDF]

, 2014
Background Most of the proteins in the Protein Data Bank (PDB) are oligomeric complexes consisting of two or more subunits that associate by rotational or helical symmetries.
Abagyan, Ruben, Orozco López, Modesto, Rueda Borrego, Manuel, Totrov, Maxim   +3 more
core   +2 more sources

EPR characterization of the heme domain of a self-sufficient cytochrome P450 (CYP116B5) [PDF]

, 2022
CYP116B5 is a self-sufficient cytochrome P450 (CYP450) with interesting catalytic properties for synthetic purposes. When isolated, its heme domain can act as a peroxygenase on different substrates of biotechnological interest.
Chiesa, Mario, Correddu, Danilo, Di Nardo, Giovanna, Famulari, Antonino, García-Rubio, Inés, Gilardi, Gianfranco   +5 more
core   +3 more sources