Results 71 to 80 of about 2,618 (230)
This paper documents the dataset obtained from the Electron Paramagnetic Resonance (EPR) study of the electronic properties of a self-sufficient cytochrome P450, CYP116B5hd, which possesses an interesting catalytic activity for synthetic purposes.
Antonino Famulari+5 more
doaj
Rotenone selectively occludes sensitivity to hypoxia in rat carotid body glomus cells [PDF]
Carotid body glomus cells release transmitters in response to hypoxia due to the increase of excitability resulting from inhibition of O2 -regulated K+ channels. However, the mechanisms involved in the detection of changes of O2 tension are unknown.
García Fernández, María+3 more
core +2 more sources
Development of Bioorthogonally Degradable Tough Hydrogels Using Enamine N‐Oxide Based Crosslinkers
Inducibly degradable enamine N‐oxide crosslinkers are integrated into tough double network hydrogels, enabling rapid and bioorthogonal degradation by aqueous diboron solutions. These chemical reagent‐responsive biomaterials maintain structural integrity during use while enabling rapid degradation when needed, making them ideal for applications in ...
Thomas T. Kim+4 more
wiley +1 more source
PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ
Intrinsic protein flexibility is of overwhelming relevance for intermolecular recognition and adaptability of highly dynamic ensemble of complexes, and the phenomenon is essential for the understanding of numerous biological processes.
Miguel Á. Casado-Combreras+12 more
doaj
EPR characterization of the heme domain of a self-sufficient cytochrome P450 (CYP116B5) [PDF]
CYP116B5 is a self-sufficient cytochrome P450 (CYP450) with interesting catalytic properties for synthetic purposes. When isolated, its heme domain can act as a peroxygenase on different substrates of biotechnological interest.
Chiesa, Mario+5 more
core +3 more sources
Porphyrin atropisomerism opens an entirely new toolbox, allowing for the precise design of a porphyrin's molecular shape. This review details how this phenomenon has been utilised across all fields of chemistry, focusing on molecular recognition, medicinal chemistry and catalysis.
Sophie Maguire+5 more
wiley +1 more source
Ferricytochrome c Directly Oxidizes Aminoacetone to Methylglyoxal, a Catabolite Accumulated in Carbonyl Stress [PDF]
Age-related diseases are associated with increased production of reactive oxygen and carbonyl species such as methylglyoxal. Aminoacetone, a putative threonine catabolite, is reportedly known to undergo metal-catalyzed oxidation to methylglyoxal, NH4 ...
Bechara, Etelvino José Henriques+8 more
core +2 more sources
The flavohemoglobin Yhb1 is a new interacting partner of the heme transporter Str3
A new mechanism for Yhb1 (orange) heme‐dependent activation involves direct interaction with the cell‐surface heme transporter Str3 (blue) in the presence of exogenous heme (red). Upon exposure to nitric oxide (˙NO), the expression of yhb1+ is induced, as its promoter is liberated from Fep1 repression (violet).
Florie Lo Ying Ping+4 more
wiley +1 more source
BackgroundCardiopulmonary bypass (CPB) lyses erythrocytes and induces lipid peroxidation, indicated by increasing plasma concentrations of free hemoglobin, F2-isoprostanes, and isofurans.
Frederic T Billings+3 more
doaj +1 more source
Study On Traditional Medicine-modern Drug Interaction And Its Molecular Mechanism Elucidation In Rat Liver [PDF]
Traditional medicines have been used for thousands of years in maintaining health as an alternative to or in conjunction with modem medicines. Ubatan tradisional telah digunakan beribu-ribu tahun untuk penjagaan kesihatan sebagai alternatif atau ...
A. Taher, Yousef
core