Results 71 to 80 of about 2,618 (230)

CYP116B5hd, a self-sufficient P450 cytochrome: A dataset of its electronic and geometrical properties

open access: yesData in Brief, 2022
This paper documents the dataset obtained from the Electron Paramagnetic Resonance (EPR) study of the electronic properties of a self-sufficient cytochrome P450, CYP116B5hd, which possesses an interesting catalytic activity for synthetic purposes.
Antonino Famulari   +5 more
doaj  

Rotenone selectively occludes sensitivity to hypoxia in rat carotid body glomus cells [PDF]

open access: yes, 2003
Carotid body glomus cells release transmitters in response to hypoxia due to the increase of excitability resulting from inhibition of O2 -regulated K+ channels. However, the mechanisms involved in the detection of changes of O2 tension are unknown.
García Fernández, María   +3 more
core   +2 more sources

Development of Bioorthogonally Degradable Tough Hydrogels Using Enamine N‐Oxide Based Crosslinkers

open access: yesAdvanced Materials, Volume 37, Issue 13, April 2, 2025.
Inducibly degradable enamine N‐oxide crosslinkers are integrated into tough double network hydrogels, enabling rapid and bioorthogonal degradation by aqueous diboron solutions. These chemical reagent‐responsive biomaterials maintain structural integrity during use while enabling rapid degradation when needed, making them ideal for applications in ...
Thomas T. Kim   +4 more
wiley   +1 more source

PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ

open access: yesComputational and Structural Biotechnology Journal, 2022
Intrinsic protein flexibility is of overwhelming relevance for intermolecular recognition and adaptability of highly dynamic ensemble of complexes, and the phenomenon is essential for the understanding of numerous biological processes.
Miguel Á. Casado-Combreras   +12 more
doaj  

EPR characterization of the heme domain of a self-sufficient cytochrome P450 (CYP116B5) [PDF]

open access: yes, 2022
CYP116B5 is a self-sufficient cytochrome P450 (CYP450) with interesting catalytic properties for synthetic purposes. When isolated, its heme domain can act as a peroxygenase on different substrates of biotechnological interest.
Chiesa, Mario   +5 more
core   +3 more sources

Porphyrin Atropisomerism as a Molecular Engineering Tool in Medicinal Chemistry, Molecular Recognition, Supramolecular Assembly, and Catalysis

open access: yesChemistry – A European Journal, Volume 30, Issue 43, August 1, 2024.
Porphyrin atropisomerism opens an entirely new toolbox, allowing for the precise design of a porphyrin's molecular shape. This review details how this phenomenon has been utilised across all fields of chemistry, focusing on molecular recognition, medicinal chemistry and catalysis.
Sophie Maguire   +5 more
wiley   +1 more source

Ferricytochrome c Directly Oxidizes Aminoacetone to Methylglyoxal, a Catabolite Accumulated in Carbonyl Stress [PDF]

open access: yes, 2013
Age-related diseases are associated with increased production of reactive oxygen and carbonyl species such as methylglyoxal. Aminoacetone, a putative threonine catabolite, is reportedly known to undergo metal-catalyzed oxidation to methylglyoxal, NH4 ...
Bechara, Etelvino José Henriques   +8 more
core   +2 more sources

The flavohemoglobin Yhb1 is a new interacting partner of the heme transporter Str3

open access: yesMolecular Microbiology, Volume 122, Issue 1, Page 29-49, July 2024.
A new mechanism for Yhb1 (orange) heme‐dependent activation involves direct interaction with the cell‐surface heme transporter Str3 (blue) in the presence of exogenous heme (red). Upon exposure to nitric oxide (˙NO), the expression of yhb1+ is induced, as its promoter is liberated from Fep1 repression (violet).
Florie Lo Ying Ping   +4 more
wiley   +1 more source

Perioperative intravenous acetaminophen attenuates lipid peroxidation in adults undergoing cardiopulmonary bypass: a randomized clinical trial.

open access: yesPLoS ONE, 2015
BackgroundCardiopulmonary bypass (CPB) lyses erythrocytes and induces lipid peroxidation, indicated by increasing plasma concentrations of free hemoglobin, F2-isoprostanes, and isofurans.
Frederic T Billings   +3 more
doaj   +1 more source

Study On Traditional Medicine-modern Drug Interaction And Its Molecular Mechanism Elucidation In Rat Liver [PDF]

open access: yes, 1998
Traditional medicines have been used for thousands of years in maintaining health as an alternative to or in conjunction with modem medicines. Ubatan tradisional telah digunakan beribu-ribu tahun untuk penjagaan kesihatan sebagai alternatif atau ...
A. Taher, Yousef
core  

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