Influence of the freezing process upon fluoride binding to hemeproteins [PDF]
Fluoride association with ferric myoglobins and hemoglobins in aqueous buffers above freezing has been well studied. We chose this reaction to investigate the feasibility of observing titration intermediates and estimating dissociation constants at the freezing temperature by electron paramagnetic resonance spectroscopy at cryogenic temperatures ...
An-Suei Yang, Arthur S. Brill
openaire +2 more sources
Abstract In the classical microbial isolation technique, the isolation process inevitably destroys all microbial interactions and thus makes it difficult to culture the many microorganisms that rely on these interactions for survival. In this study, we designed a simple coculture technique named the “sandwich agar plate method,” which maintains ...
Jing Zhang+8 more
wiley +1 more source
Application of Brownian motion theory to the analysis of membrane channel ionic trajectories calculated by molecular dynamics [PDF]
This paper shows how Brownian motion theory can be used to analyze features of individual ion trajectories in channels as calculated by molecular dynamics, and that its use permits more precise determinations of diffusion coefficients than would ...
Aalfs, Cora M.+6 more
core +2 more sources
Mechanistics of pH‐Dependent Sulfmyoglobin Formation: Spin Control and His64 Proton Relay
The chemistry of hydrogen sulfide (H2S) has been directed towards physiologically relevant hemeproteins, including myoglobin, hemoglobin, and other similar proteins. Despite substantial efforts, there remains a need to elucidate the mechanism and identify the species involved in the reaction between oxy‐hemeproteins and H2S. Here, we summarize both our
Angel D. Rodriguez-Mackenzie+5 more
wiley +1 more source
Aki associated with macroscopic glomerular hematuria: Clinical and pathophysiologic consequences [PDF]
Hematuria is a common finding in various glomerular diseases. This article reviews the clinical data on glomerular hematuria and kidney injury, as well as the pathophysiology of hematuria-associated renal damage.
Alberto Ortiz+29 more
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Fast ferrous heme-NO oxidation in nitric oxide synthases. [PDF]
International audienceDuring catalysis, the heme in nitric oxide synthase (NOS) binds NO before releasing it to the environment. Oxidation of the NOS ferrous heme-NO complex by O2 is key for catalytic cycling, but the mechanism is unclear.
Santolini, J.+2 more
core +3 more sources
The cytochrome P450 family consists of ubiquitous monooxygenases with the potential to perform a wide variety of catalytic applications. Among the members of this family, CYP116B5hd shows a very prominent resistance to peracid damage, a property that ...
Antonino Famulari+6 more
doaj +1 more source
Antioxidantes dietéticos para la prevención de la periodontitis crónica y su tratamiento. Una revisión de las evidencias actuales procedentes de estudios en animales y humanos [PDF]
Objetivos. Dada la relación existente entre periodontitis crónica y altos niveles de estrés oxidativo, esta revisión pretende clarificar qué papel puede desempeñar la ingesta de los diferentes antioxidantes de la dieta en el mantenimiento de un ...
Bullon, Pedro
core
Gold nanoparticles - the theranostic challenge for PPPM: nanocardiology application [PDF]
The article overviews the potential biomedical applications of nanoscale gold particles for predictive, preventive and personalised nanomedicine in cardiology.
Ilya M Yemets+5 more
core +1 more source
Molecular simulations of globins: Exploring the relationship between structure, dynamics and function [PDF]
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32392The discovery in the last two decades of novel members of the globin superfamily has challenged the conventional view about the structure and function of globins.
Arroyo, Pau+10 more
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