Results 81 to 90 of about 2,605 (236)

Aki associated with macroscopic glomerular hematuria: Clinical and pathophysiologic consequences [PDF]

open access: yes, 2012
Hematuria is a common finding in various glomerular diseases. This article reviews the clinical data on glomerular hematuria and kidney injury, as well as the pathophysiology of hematuria-associated renal damage.
Alberto Ortiz   +29 more
core   +2 more sources

Porphyrin Atropisomerism as a Molecular Engineering Tool in Medicinal Chemistry, Molecular Recognition, Supramolecular Assembly, and Catalysis

open access: yesChemistry – A European Journal, Volume 30, Issue 43, August 1, 2024.
Porphyrin atropisomerism opens an entirely new toolbox, allowing for the precise design of a porphyrin's molecular shape. This review details how this phenomenon has been utilised across all fields of chemistry, focusing on molecular recognition, medicinal chemistry and catalysis.
Sophie Maguire   +5 more
wiley   +1 more source

Perioperative intravenous acetaminophen attenuates lipid peroxidation in adults undergoing cardiopulmonary bypass: a randomized clinical trial.

open access: yesPLoS ONE, 2015
BackgroundCardiopulmonary bypass (CPB) lyses erythrocytes and induces lipid peroxidation, indicated by increasing plasma concentrations of free hemoglobin, F2-isoprostanes, and isofurans.
Frederic T Billings   +3 more
doaj   +1 more source

Study On Traditional Medicine-modern Drug Interaction And Its Molecular Mechanism Elucidation In Rat Liver [PDF]

open access: yes, 1998
Traditional medicines have been used for thousands of years in maintaining health as an alternative to or in conjunction with modem medicines. Ubatan tradisional telah digunakan beribu-ribu tahun untuk penjagaan kesihatan sebagai alternatif atau ...
A. Taher, Yousef
core  

The flavohemoglobin Yhb1 is a new interacting partner of the heme transporter Str3

open access: yesMolecular Microbiology, Volume 122, Issue 1, Page 29-49, July 2024.
A new mechanism for Yhb1 (orange) heme‐dependent activation involves direct interaction with the cell‐surface heme transporter Str3 (blue) in the presence of exogenous heme (red). Upon exposure to nitric oxide (˙NO), the expression of yhb1+ is induced, as its promoter is liberated from Fep1 repression (violet).
Florie Lo Ying Ping   +4 more
wiley   +1 more source

Fast ferrous heme-NO oxidation in nitric oxide synthases. [PDF]

open access: yes, 2009
International audienceDuring catalysis, the heme in nitric oxide synthase (NOS) binds NO before releasing it to the environment. Oxidation of the NOS ferrous heme-NO complex by O2 is key for catalytic cycling, but the mechanism is unclear.
Santolini, J.   +2 more
core   +4 more sources

Fungal systems for lignocellulose deconstruction: From enzymatic mechanisms to hydrolysis optimization

open access: yesGCB Bioenergy, Volume 16, Issue 5, May 2024.
Biomass contains complex sugars and aromatic polymers that have the potential to serve as sustainable alternatives to fossil fuels and chemicals. Fungi possess specialized enzyme systems capable of breaking down lignocellulose into fermentable building blocks. This review analyses recent advancements in intricate fungal decomposition toolkits, shedding
Fengyun Ren   +5 more
wiley   +1 more source

Cultivating the uncultured: Harnessing the “sandwich agar plate” approach to isolate heme‐dependent bacteria from marine sediment

open access: yesmLife, Volume 3, Issue 1, Page 143-155, March 2024.
Abstract In the classical microbial isolation technique, the isolation process inevitably destroys all microbial interactions and thus makes it difficult to culture the many microorganisms that rely on these interactions for survival. In this study, we designed a simple coculture technique named the “sandwich agar plate method,” which maintains ...
Jing Zhang   +8 more
wiley   +1 more source

Gold nanoparticles - the theranostic challenge for PPPM: nanocardiology application [PDF]

open access: yes, 2013
The article overviews the potential biomedical applications of nanoscale gold particles for predictive, preventive and personalised nanomedicine in cardiology.
Ilya M Yemets   +5 more
core   +1 more source

Mechanistics of pH‐Dependent Sulfmyoglobin Formation: Spin Control and His64 Proton Relay

open access: yesJournal of Chemistry, Volume 2024, Issue 1, 2024.
The chemistry of hydrogen sulfide (H2S) has been directed towards physiologically relevant hemeproteins, including myoglobin, hemoglobin, and other similar proteins. Despite substantial efforts, there remains a need to elucidate the mechanism and identify the species involved in the reaction between oxy‐hemeproteins and H2S. Here, we summarize both our
Angel D. Rodriguez-Mackenzie   +5 more
wiley   +1 more source

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