Results 51 to 60 of about 1,955 (147)

Phosphorylation of cytochrome c at tyrosine 48 finely regulates its binding to the histone chaperone SET/TAF‐Iβ in the nucleus

Protein Science, Volume 33, Issue 12, December 2024.
Abstract Post‐translational modifications (PTMs) of proteins are ubiquitous processes present in all life kingdoms, involved in the regulation of protein stability, subcellular location and activity. In this context, cytochrome c (Cc) is an excellent case study to analyze the structural and functional changes induced by PTMS as Cc is a small ...
Joaquin Tamargo‐Azpilicueta, Miguel Á. Casado‐Combreras, Rafael L. Giner‐Arroyo, Adrián Velázquez‐Campoy, Inmaculada Márquez, José L. Olloqui‐Sariego, Miguel A. De la Rosa, Irene Diaz‐Moreno   +7 more
wiley   +1 more source

Porphyrin Atropisomerism as a Molecular Engineering Tool in Medicinal Chemistry, Molecular Recognition, Supramolecular Assembly, and Catalysis

Chemistry – A European Journal, Volume 30, Issue 43, August 1, 2024.
Porphyrin atropisomerism opens an entirely new toolbox, allowing for the precise design of a porphyrin's molecular shape. This review details how this phenomenon has been utilised across all fields of chemistry, focusing on molecular recognition, medicinal chemistry and catalysis.
Sophie Maguire, Grant Strachan, Karolis Norvaiša, Claire Donohoe, Lígia C. Gomes‐da‐Silva, Mathias O. Senge   +5 more
wiley   +1 more source

The flavohemoglobin Yhb1 is a new interacting partner of the heme transporter Str3

Molecular Microbiology, Volume 122, Issue 1, Page 29-49, July 2024.
A new mechanism for Yhb1 (orange) heme‐dependent activation involves direct interaction with the cell‐surface heme transporter Str3 (blue) in the presence of exogenous heme (red). Upon exposure to nitric oxide (˙NO), the expression of yhb1+ is induced, as its promoter is liberated from Fep1 repression (violet).
Florie Lo Ying Ping, Tobias Vahsen, Ariane Brault, Raphaël Néré, Simon Labbé   +4 more
wiley   +1 more source

Fungal systems for lignocellulose deconstruction: From enzymatic mechanisms to hydrolysis optimization

GCB Bioenergy, Volume 16, Issue 5, May 2024.
Biomass contains complex sugars and aromatic polymers that have the potential to serve as sustainable alternatives to fossil fuels and chemicals. Fungi possess specialized enzyme systems capable of breaking down lignocellulose into fermentable building blocks. This review analyses recent advancements in intricate fungal decomposition toolkits, shedding
Fengyun Ren, Fan Wu, Xin Wu, Tongtong Bao, Yucheng Jie, Le Gao   +5 more
wiley   +1 more source

Cultivating the uncultured: Harnessing the “sandwich agar plate” approach to isolate heme‐dependent bacteria from marine sediment

mLife, Volume 3, Issue 1, Page 143-155, March 2024.
Abstract In the classical microbial isolation technique, the isolation process inevitably destroys all microbial interactions and thus makes it difficult to culture the many microorganisms that rely on these interactions for survival. In this study, we designed a simple coculture technique named the “sandwich agar plate method,” which maintains ...
Jing Zhang, Qi‐Yun Liang, Da‐Shuai Mu, Fengbai Lian, Ya Gong, Mengqi Ye, Guan‐Jun Chen, Yuqi Ye, Zong‐Jun Du   +8 more
wiley   +1 more source

Improved method for assembly of hemeprotein neuronal NO-synthase heterodimers [PDF]

Analytical Biochemistry, 2016
The assembly of mutated and wild type monomers into functional heterodimeric hemeproteins has provided important mechanistic insights. As in the case of NO synthase (NOS), the existing methods to make such heterodimeric NOSs are inefficient and labor intensive with typical yields of about 5%.
Yoshihiro, Morishima, Haoming, Zhang, Miranda, Lau, Yoichi, Osawa   +3 more
openaire   +2 more sources

Genetic Polymorphisms in CYP2 Gene Family in Bulgarian Individuals and their Clinical Implications

Acta Medica Bulgarica
The cytochrome P450 superfamily consists of hemeproteins involved in the detoxication of different xenobiotics, including drugs. The CYP2 gene family is responsible for the metabolism of 80% of the drugs in clinical use.
Yovinska S., Bakalov D., Mihova K., Kamenarova K., Kaneva R., Nikolov R., Dimova I.   +6 more
doaj   +1 more source

Influence of Saccharides on the Stabilization of Frozen Hemeprotein.

NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI, 1998
糖類による凍結Hbの変性沈殿量,誘導形態,酸素親和性の生理機能に及ぼす影響を試験した.凝固沈殿量はシークロース,グリセロール,トレハロースとも0.4%以上の添加で,凍結期間7ヵ月の長期においても,認められなかった.0.2%添加で,わずかに沈殿が認められたが,糖無添加の3.6%に比べて著しく低かった.メト化抑制効果はシュクロース,グリセロールでほぼ同等であった.その効果は糖濃度と正の相関であった.7カ月の長期冷凍において,metHbの生成量は無添加で51%,1.6%添加で8%以下,6%添加で4%以下であった.トレハロースは1.6～3%添加のとき,metHbの生成量が最小になった.冷凍によって,糖濃度が低いほどHbの酸素平衡曲線はシグモイド型から双曲線型へ移行した.シェクロース,グリセロール ...
IZUMIMOTO, Masatoshi, ZHU, Yongning
openaire   +2 more sources

Demonstration that spleen green hemeprotein is identical to granulocyte myeloperoxidase

Journal of Biological Chemistry, 1989
The biochemical, spectroscopic, enzymatic, and redox properties of spleen myeloperoxidase, a peroxidase formerly called "spleen green hemeprotein," and granulocyte myeloperoxidase were compared by electrophoresis, amino-terminal amino acid sequences, optical and EPR spectroscopy, steady-state enzyme kinetics, and oxidation-reduction potential.
M, Ikeda-Saito, H C, Lee, K, Adachi, H S, Eck, R C, Prince, K S, Booth, W S, Caughey, S, Kimura   +7 more
openaire   +2 more sources

The Purity of Two Commercial Hemeproteins. [PDF]

Acta Chemica Scandinavica, 1985
K. G. Paul, P. I. Ohlson, B. Nordén, M. L. Smith, Gotfryd Kupryszewski, Bo Wigilius   +5 more
openaire   +2 more sources