Results 41 to 50 of about 2,121 (177)

Algorithmic Identification of Murzymes and Murburn Mechanisms Based on Structural, Theoretical, Experimental, and Generic Features

BioMed Research International, Volume 2026, Issue 1, 2026.
Murburn concept is a decade‐old theorization for explaining several cellular redox‐metabolic and electro/mechanophysiological outcomes. It stems from “mured burning”, connoting delocalized stochastic electron‐transfer processes, involving diffusible reactive species (DRS).
Kelath Murali Manoj, Vinith Rejathalal, Amrit Subramanian, Pathange Omkareshwara Rao, P. Unnikrishnan, K. P. Soman, Nahit Gencer   +6 more
wiley   +1 more source

Genome-wide structural and evolutionary analysis of the P450 monooxygenase genes (P450ome) in the white rot fungus Phanerochaete chrysosporium : Evidence for gene duplications and extensive gene clustering

BMC Genomics, 2005
Background Phanerochaete chrysosporium, the model white rot basidiomycetous fungus, has the extraordinary ability to mineralize (to CO2) lignin and detoxify a variety of chemical pollutants.
Yadav Jagjit S, Chakraborty Ranajit, Doddapaneni Harshavardhan   +2 more
doaj   +1 more source

Quantitative Treatments for Explaining the Mechanism and Kinetics of Catalytic Electron Transfers in Murburn Processes, Particularly Involving Heme Enzymes Like (Per)oxidases and P450s

BioMed Research International, Volume 2026, Issue 1, 2026.
The seminal Michaelis–Menten theorization for biological catalysis was based on “transition state” (TS), involving the formation of a topologically complementary substrate (S) and enzyme (E) complex (ES) at the “active site” of the latter. Rudolph Marcus put forth the theory of outer sphere electron transfer (ET) in a “donor–acceptor” TS complex, which
Kelath Murali Manoj, Daniel Andrew Gideon, Philip Moses Samuel, Suhotra Das, Nahit Gencer   +4 more
wiley   +1 more source

Acetylated Epigallocatechin Gallate and Ascorbyl Palmitate: Comparative Study on Antioxidant Activity and Retardation of Lipid Oxidation in Fish Mince and Shrimp Oil

Journal of Food Science, Volume 90, Issue 10, October 2025.
ABSTRACT Antioxidant activities of acetylated epigallocatechin gallate (A‐EGCG) and ascorbyl palmitate (AP) were compared using different in vitro assays and food model systems. Both A‐EGCG and AP exhibited DPPH and ABTS radical scavenging activities and reducing power. AP demonstrated greater scavenging efficacy toward both radicals than A‐EGCG (p < 0.
Bharathipriya Rajasekaran, Min‐Hsiung Pan, Natchaphol Buamard, Bin Zhang, Jun Tae Kim, Soottawat Benjakul   +5 more
wiley   +1 more source

Structure and dynamics of hemeproteins using X-ray Absorption Spectroscopy

, 2009
Experimental investigations on protein dynamics are usually carried out in solution; however, in most cases, the determination of protein structure is done by crystallography that relies on the diffraction properties of the protein arranged in a three ...
Arcovito Alessandro, Alessandro Arcovito, S. Della Longa, D'Angelo Paola, D'ANGELO, Paola, DELLA LONGA, STEFANO   +5 more
core   +1 more source

Nitric Oxide Binding Geometry in Heme-Proteins: Relevance for Signal Transduction

Antioxidants
Nitric oxide (NO) synthesis, signaling, and scavenging is associated to relevant physiological and pathological events. In all tissues and organs, NO levels and related functions are regulated at different levels, with heme proteins playing pivotal roles.
Giovanna De Simone, Alessandra di Masi, Diego Sbardella, Paolo Ascenzi, Massimiliano Coletta   +4 more
doaj   +1 more source

The Urea Cycle in Connection to Polyamine Metabolism in Higher Plants: New Perspectives on a Central Pathway

Physiologia Plantarum, Volume 177, Issue 3, May/June 2025.
ABSTRACT The ornithine‐urea cycle is a biochemical pathway primarily found in animals, where it plays a crucial role in the re‐assimilation of ammonium and the removal of excess nitrogen in the form of urea. In lower photosynthetic eukaryotes, it contributes to metabolic responses during episodes of high nitrogen availability.
J. Buezo, M. Urra, E. M. González, R. Alcázar, D. Marino, J. F. Moran   +5 more
wiley   +1 more source

Investigations of Ultrafast Dynamics of Photoexcited Hemeproteins and Iodomethane in Condensed Phase Using Transient Raman and Absorption Spectroscopies.

, 1993
This dissertation describes the development and application of transient Raman and absorption spectroscopies using 8 ps laser pulses for the study of photoexcitation dynamics of hemeproteins and CH$\sb3$I in the condensed phase.
Zhu, Huiping
core   +1 more source

Development of Bioorthogonally Degradable Tough Hydrogels Using Enamine N‐Oxide Based Crosslinkers

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
Inducibly degradable enamine N‐oxide crosslinkers are integrated into tough double network hydrogels, enabling rapid and bioorthogonal degradation by aqueous diboron solutions. These chemical reagent‐responsive biomaterials maintain structural integrity during use while enabling rapid degradation when needed, making them ideal for applications in ...
Thomas T. Kim, Deep Malu, Dongjing He, Yuhang Hu, Justin Kim   +4 more
wiley   +1 more source

Evolutionary Pro‐To‐Thr Mutation in the Intrinsically Disordered Domain of ANP32 Family Members Modulates Their Target Binding Modes

Advanced Science, Volume 12, Issue 12, March 27, 2025.
Protein evolution usually lies on mutations at disordered domains to promote novel functions and regulations. Here it is demonstrated that this is the case of ANP32A and ANP32B, two paralogs with apparently similar structures and functions, where a single amino‐acid substitution in the disordered domain triggers the extended‐to‐compact conformational ...
Blanca Baños‐Jaime, Ana B. Uceda‐Mayo, Francisco Rivero‐Rodríguez, Miguel Á. Casado‐Combreras, Alejandro Velázquez‐Cruz, Adrián Velázquez‐Campoy, Laura Corrales‐Guerrero, Miguel A. De la Rosa, Irene Díaz‐Moreno   +8 more
wiley   +1 more source