Results 21 to 30 of about 1,955 (147)
Recent Approaches for Manipulating Globin Gene Expression in Treating Hemoglobinopathies
Frontiers in Genome Editing, 2021 Tissue oxygenation throughout life depends on the activity of hemoglobin (Hb) one of the hemeproteins that binds oxygen in the lungs and secures its delivery throughout the body.
Claudio Mussolino +2 more
doaj +1 more source
Hsp90 in Human Diseases: Molecular Mechanisms to Therapeutic Approaches
Cells, 2022 The maturation of hemeprotein dictates that they incorporate heme and become active, but knowledge of this essential cellular process remains incomplete. Studies on chaperon Hsp90 has revealed that it drives functional heme maturation of inducible nitric
Mamta P. Sumi, Arnab Ghosh
doaj +1 more source
New insights into the role of heme oxygenase-1 in acute kidney injury
Kidney Research and Clinical Practice, 2020 Acute kidney injury (AKI) is attended by injury-related biomarkers appearing in the urine and serum, decreased urine output, and impaired glomerular filtration rate.
Meryl Nath, Anupam Agarwal
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Mechanisms of Neuronal Damage in Acute Hepatic Porphyrias
Diagnostics, 2021 Porphyrias are a group of congenital and acquired diseases caused by an enzymatic impairment in the biosynthesis of heme. Depending on the specific enzyme involved, different types of porphyrias (i.e., chronic vs. acute, cutaneous vs.
Andrea Ricci +3 more
doaj +1 more source
Rhabdomyolysis as cause, consequence, or mimicker of myocardial infarction: A case report
Clinical Case Reports, Volume 11, Issue 11, November 2023., 2023 Key Clinical Message A timely diagnosis is essential to start appropriate therapy and to reduce risks of life‐threatening complications of rhabdomyolysis. Some cases can undergo differential diagnosis with other clinical conditions, e.g., myocardial infarction.
Marina Nasello +11 more
wiley +1 more source
Optimization of Hnox Protein Production in Escherichia Coli
Cumhuriyet Science Journal, 2017 Hemeproteinscarry a variety of different functions in organisms ranging from steroidbiosynthesis to respiration, signaling to drug metabolism. In industry,hemeproteins are used for production of drugs such as: pravastatin for loweringcholesterol ...
Nur Başak Sürmeli
doaj +1 more source
Open Chemistry, 2020 A unique method was used to synthesize extremely stable silver stearate nanoparticles (AgStNPs) incorporated in an organic-based monolith. The facile strategy was then used to selectively isolate hemeproteins, myoglobin (Myo)
Alzahrani Eman
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Hypoxic Regulation of the Large-Conductance, Calcium and Voltage-Activated Potassium Channel, BK
Frontiers in Physiology, 2021 Hypoxia is a condition characterized by a reduction of cellular oxygen levels derived from alterations in oxygen balance. Hypoxic events trigger changes in cell-signaling cascades, oxidative stress, activation of pro-inflammatory molecules, and growth ...
Sara V. Ochoa +9 more
doaj +1 more source
Hydrogen Sulfide and Hemeproteins: Knowledge and Mysteries [PDF]
Antioxidants & Redox Signaling, 2011 Historically, hydrogen sulfide (H(2)S) has been regarded as a poisonous gas, with a wide spectrum of toxic effects. However, like ·NO and CO, H(2)S is now referred to as a signaling gas involved in numerous physiological processes. The list of reports highlighting the physiological effects of H(2)S is rapidly expanding and several drug candidates are ...
Ruth, Pietri +2 more
openaire +2 more sources
Advanced Science, Volume 10, Issue 29, October 17, 2023., 2023 This study focuses on the molecular action of two histone chaperones: SET/template‐activating factor‐Iβ and nucleophosmin 1. It is shown how these chaperones have specificity for fully dismantled nucleosomes, characterized the histone eviction (removal) process, and its modulation by cytochrome c.
Pedro Buzón +5 more
wiley +1 more source