Improved method for assembly of hemeprotein neuronal NO-synthase heterodimers [PDF]
Analytical Biochemistry, 2016 The assembly of mutated and wild type monomers into functional heterodimeric hemeproteins has provided important mechanistic insights. As in the case of NO synthase (NOS), the existing methods to make such heterodimeric NOSs are inefficient and labor intensive with typical yields of about 5%.
Yoshihiro, Morishima +3 more
openaire +2 more sources
Supramolecular electrode assemblies for bioelectrochemistry [PDF]
, 2017 For more than three decades, the field of bioelectrochemistry has provided novel insights into the catalytic mechanisms of enzymes, the principles that govern biological electron transfer, and has elucidated the basic principles for bioelectrocatalytic ...
Armstrong +74 more
core +1 more source
Genetic Polymorphisms in CYP2 Gene Family in Bulgarian Individuals and their Clinical Implications
Acta Medica BulgaricaThe cytochrome P450 superfamily consists of hemeproteins involved in the detoxication of different xenobiotics, including drugs. The CYP2 gene family is responsible for the metabolism of 80% of the drugs in clinical use.
Yovinska S. +6 more
doaj +1 more source
Immobilization of proteins in silica gel: Biochemical and biophysical properties [PDF]
, 2015 The development of silica-based sol-gel techniques compatible with the retention of protein structure and function started more than 20 years ago, mainly for the design of biotechnological devices or biomedical applications.
Abbruzzetti, S +8 more
core +1 more source
Mitochondrial Dysfunction Induces Formation of Lipid Droplets as a Generalized Response to Stress [PDF]
, 2013 Lipid droplet (LD) formation is a hallmark of cellular stress. Cells attempt to combat noxious stimuli by switching their metabolism from oxidative phosphorylation to glycolysis, sparing resources in LDs for generating cellular reducing power and for ...
Choi, Augustine M. K. +3 more
core +3 more sources
Iron transfer and storage proteins [PDF]
, 2013 Željezo je vrlo bitan element za temeljne metaboličke procese. S obzirom na činjenicu da je neophodan za niz funkcija, organizmi ga moraju pohranjivati na način da bude netoksičan i brzo dostupan.
Kuhanec, Antonija
core +2 more sources
Cofactor engineering for enhancing the flux of metabolic pathways. [PDF]
, 2014 The manufacture of a diverse array of chemicals is now possible with biologically engineered strains, an approach that is greatly facilitated by the emergence of synthetic biology.
Akhtar, MK, Jones, PR
core +3 more sources
Reaction intermediates and molecular mechanism of Peroxynitrite activation by NO synthases [PDF]
, 2016 The activation of peroxynitrite (PN) by hemoproteins, which leads to its detoxification or on the contrary to the enhancement of its cytotoxic activity, is a reaction of physiological importance that is still poorly understood. It has been known for some
Adak +63 more
core +3 more sources
The photosynthetic cytochrome c550 from the diatom Phaeodactylum tricornutum [PDF]
, 2016 The photosynthetic cytochrome c550 from the marine diatom Phaeodactylum tricornutum has been purified and characterized. Cytochrome c550 is mostly obtained from the soluble cell extract in relatively large amounts. In addition, the protein appeared to be
Bernal Bayard, Pilar +7 more
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Antioxidant Properties of Propofol [PDF]
, 2006 Propofol is an intravenous sedative-hypnotic agent indicated for induction and maintenance of general anesthesia as well as for sedation of intubated, mechanically ventilated adults in intensive care units (ICU).
Astuto, Marinella +6 more
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