Results 131 to 140 of about 43,983 (296)

Terpene Hydroperoxides as Lipid Peroxidation Inducers: Biomimetic and HaCaT Cell Studies in Allergic Contact Dermatitis

open access: yesContact Dermatitis, EarlyView.
Fragrance terpene hydroperoxides from limonene, linalool, and geraniol induced the formation of lipid peroxidation products when incubated with PLPC liposomes or in vitro with HaCaT keratinocytes. Lipid peroxidation products included aldehydes, ketones, and hydroperoxides.
Aaron I. Moore   +6 more
wiley   +1 more source

Role of cytochrome c heme lyase in the import of cytochrome c into mitochondria [PDF]

open access: yes, 1988
The import of cytochrome c into Neurospora crassa mitochondria was examined at distinct stages in vitro. The precursor protein, apocytochrome c, binds to mitochondria with high affinity and specificity but is not transported completely across the outer ...
Hergersberg, Christoph   +2 more
core  

Sirt3 Rescues Porphyromonas gingivalis‐Impaired Cementogenesis via SOD2 Deacetylation

open access: yesCell Proliferation, EarlyView.
Sirt3 deacetylated SOD2 via K68 to orchestrate P.g.‐impaired cementogenesis. Reestablishment of the Sirt3/SOD2 axis by honokiol reduced SOD2 acetylation and facilitated cementogenesis. ABSTRACT The keystone pathogen Porphyromonas gingivalis (P.g.) is responsible for cementum resorption in periodontitis; however, the mechanism involved in it remains ...
Xin Huang   +6 more
wiley   +1 more source

Stabilization of Aqueous Hemin Solutions. [PDF]

open access: bronze, 1958
A.C. Maehly   +5 more
openalex   +1 more source

Role of Hemin and Growth Media on the Autofluorescence of Streptococcus mutans [PDF]

open access: yes, 2015
poster abstractAbstract Carious lesions fluoresce under blue light. The primary cariogenic bacterium Streptococcus mutans has been shown previously to fluoresce within blue light wavelengths.
Eckert, George J.   +2 more
core  

Hemin and iron increase synthesis and trigger export of xanthine oxidoreductase from hepatocytes to the circulation

open access: yesRedox Biology, 2023
We recently reported a previously unknown salutary role for xanthine oxidoreductase (XOR) in intravascular heme overload whereby hepatocellular export of XOR to the circulation was identified as a seminal step in affording protection.
Evan R. DeVallance   +12 more
doaj  

Porphyromonas gingivalis outer membrane vesicles increase vascular permeability by inducing stress fiber formation and degrading vascular endothelial‐cadherin in endothelial cells

open access: yesThe FEBS Journal, Volume 292, Issue 7, Page 1696-1709, April 2025.
Porphyromonas gingivalis (Pg), a periodontal bacterium implicated in systemic diseases, release outer membrane vesicles (OMVs). Here, we show that Pg OMVs induce stress fiber formation and degrade vascular endothelial cadherin (VEc) via lysosomes and endosomes in endothelial cells, leading to hyper‐permeability.
Mana Mekata   +7 more
wiley   +1 more source

A signal transduction blind spot: the function of adenylyl cyclase transmembrane domains

open access: yesThe FEBS Journal, EarlyView.
Transmembrane adenylyl cyclases (tmACs) are essential for synthesising the universal second messenger cyclic AMP. All tmACs share a common topology that includes a large 12‐helix transmembrane (TM) domain. This domain accounts for ~ 35% of the coding sequence but its function is still an open question.
Ryan S. Dowsell, Matthew G. Gold
wiley   +1 more source

A guide to heat shock factors as multifunctional transcriptional regulators

open access: yesThe FEBS Journal, EarlyView.
The heat shock factors (HSFs) are evolutionarily conserved transcription factors best known as regulators of molecular chaperone genes in response to heat shock and other protein‐damaging stresses. Vertebrate HSFs, HSF1‐5, HSFX, and HSFY, are implicated in various physiological and pathological processes, including organismal development and cancer ...
Hendrik S. E. Hästbacka   +3 more
wiley   +1 more source

Study on porphyromonas gingivalis- and porphyromonas endodontalis- mediated signaling pathway [PDF]

open access: yes, 2019
It is known that anaerobic microbes like Porphyromonas gingivalis (P. gingivalis) are involved in the progression and initiation of multiple forms of periodontal disease such as chronic periodontitis.
Alamry, Nujud
core  

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