Results 111 to 120 of about 39,725 (289)

Hemin/G-quadruplex DNAzyme for Designing of Electrochemical Sensors

International Journal of Electrochemical Science, 2015
Guanine-rich nucleic acid sequence can fold into guanine quadruplex (G-quadruplex) that is found to complex tightly with hemin to form the hemin/G-quadruplex.
Guo-Cheng Han, Xiao-Zhen Feng, Zhencheng   +2 more
doaj   +1 more source

Synthesis, Electrochemistry, In Vitro Antiprotozoal Efficacy and Mechanistic Study of Novel ‘Ferrantoin’ and Related Derivatives

Applied Organometallic Chemistry, Volume 40, Issue 7, July 2026.
1,2‐Disubstituted ferrocene analogues bearing hydantoin or rhodanine synthons were synthesised and assessed for antitrypanosomatid activity. An antileishmanial early lead, analogue 23, acting through ROS generation and hence oxidative stress, was uncovered.
Maryna Saayman, Janine Aucamp, Helena D. Janse van Rensburg, Christina Kannigadu, Rotondwa Mphephu, Andrew J. Swarts, Keisuke Suganuma, David D. N'Da   +7 more
wiley   +1 more source

Enhanced peroxidase-like properties of graphene-hemin-composite decorated with Au nanoflowers as electrochemical aptamer biosensor for the detection of K562 leukemia cancer cells

, 2016
Graphene composites with hemin and gold nanoparticles show a better performance for hydrogen peroxide decomposition compared to that of the three components alone or duplex/hybrid complexes.
Li Niu (727239), Hong Zhou (29614), Meirong Cui (4678168), Jing Liu (13076079), Shusheng Zhang (1500898)   +4 more
core  

Polystyrene–Hemin Dots for Chemiluminescence Imaging

, 2019
Chemiluminescence (CL) imaging has high sensitivity with significantly increased signal-to-background ratio due to no interferences of light source and autofluorescence.
Xiangyi Huang (1783891), Liyun Deng (5145266), Yuhan Teng (6852230), Yuhan Teng, Min Zhou (173135), Min Zhou, Mengdi Li, Jicun Ren, Jicun Ren (1727761), Mengdi Li (6409472), Liyun Deng, Xiangyi Huang   +11 more
core   +1 more source

Crystal Structure and Conformational Dynamics of N─N Bond‐Forming Piperazate Synthase

ChemBioChem, Volume 27, Issue 12, 26 June 2026.
Piperazate synthases (PZSs) catalyze the key N─N bond formation in the biosynthesis of the rare amino acid piperazic acid. X‐ray crystal structures of apo‐ and holo‐SbPZS show a dimeric enzyme with two heme‐containing active sites, where histidine residues coordinate the iron centers.
Nikita Pal, Simon Schröder, Amit Singh Sahrawat, Christian C. Gruber, Martin A. Hayes, Bastian Daniel, Sandy Schmidt, Karl Gruber   +7 more
wiley   +1 more source

Multifunctional Bio‐Based Packaging for Perishable Foods: Structural Design, Scalable Fabrication, and Versatile Applications

Advanced Materials, Volume 38, Issue 33, 12 June 2026.
An overview of design principles and scalable fabrication strategies for multifunctional bio‐based packaging. Radiative cooling films, modified‐atmosphere films/membranes, active antimicrobial/antioxidant platforms, intelligent optical/electrochemical labels, and superhydrophobic surfaces are co‐engineered from material chemistry to mesoscale structure
Lei Zhang, Jiaqi Zhang, Mei Cui, Wei Qi, Renliang Huang, Rongxin Su, Kai Zhang   +6 more
wiley   +1 more source

Involvement of EGFR-AKT signaling in hemin-induced neurotoxicity

Experimental Biology and Medicine
Intracerebral hemorrhage (ICH), as bleeding from ruptured vessels within the brain, is the second leading neuropathological problem following ischemic stroke.
Hui-Ju Huang, Yang-Jie Tseng, I-Jung Lee, Yu-Li Lo, Anya Maan-Yuh Lin, Anya Maan-Yuh Lin, Anya Maan-Yuh Lin   +6 more
doaj   +1 more source

Improvement of a Hemin Standard by Recrystallization

Experimental Biology and Medicine, 1952
Summary1. The purity of crude hemin preparations used, as determined by their iron content, was improved by recrystallization. 2. Crude hemin preparations in borate buffer showed variable extinction coefficients at any wavelength selected along the flat portions of the absorption spectra.
V S, BAVISOTTO, G H, PRITHAM, M E, CHILCOTE   +2 more
openaire   +2 more sources

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, Volume 13, Issue 33, 15 June 2026.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Biomimetic Nanoplatform for Targeted Glioblastoma Therapy via Concurrently Triggering GPX4/DHODH Mediated Ferroptosis

Advanced Science, Volume 13, Issue 31, 4 June 2026.
Considering the great challenge in Glioblastoma multiforme (GBM) treatment, the authors designed and synthesized a multifunctional nanoplatform that effectively induced ferroptosis by synergetically inhibiting intrinsic intrisinc anti‐ferroptosis proteins, GPX4 & DHODH, and realized excellent in vitro and in vivo anti‐GBM effect.
Guodong Ren, Xuewei Wang, Panpan Li, Hao Wu, Zhifei Bi, Qi Gao, Bolong Ma, Zixuan Tian, Jianfei Liu, Fuqiang Feng, Wen Liu, Lin Li, Chengwu Zhang   +12 more
wiley   +1 more source