Results 101 to 110 of about 39,725 (289)

Porphyromonas gingivalis Outer Membrane Vesicles‐Associated DNA Triggers Inflammation by Inducing IL‐6 in Astrocytes

open access: yesMolecular Oral Microbiology, EarlyView.
Pg releases OMVs which contain Pg genomic DNA. The Pg OMVs‐associated DNA is incorporated into astrocytes via endocytosis and increases IL‐6 mRNA expression via TLR9. These effects of Pg OMVs may induce neuroinflammation, which could contribute to the onset and progression of AD in periodontal disease.
Ayu Takai   +7 more
wiley   +1 more source

Dietary inclusion of cyanobacteria Arthrospira (Spirulina platensis) spp. decreases the aggravating effect of hemin from red meat in a rat colorectal carcinogenesis model

open access: yesFuture Foods
Colorectal cancer (CRC) risk, associated with a high intake of red/processed meat, may be related to hemin. A potential chemopreventive agent, Arthrospira (Spirulina platensis) spp. (AP) is a cyanobacteria employed as a functional food with the potential
Luis Manuel Sarmiento-Machado   +4 more
doaj   +1 more source

Citizen‐Centered Public Service Design in Agile Digital Transformation: Insights From Public Mobility Services

open access: yesPublic Administration, EarlyView.
ABSTRACT The aim of this study is to highlight the critical role of human‐centered design approach as a foundational element in the agile digital transformation of public service design. Grounded in service‐design principles and public‐service logic, it analyses how agencies adopt agile practices and involve stakeholders in co‐design of disrupted ...
Hemin Choi, Maria Cucciniello
wiley   +1 more source

Preparation of Hydrogen Peroxide Sensitive Nanofilms by a Layer-by-Layer Technique

open access: yesNanomaterials, 2018
H2O2-sensitive nanofilms composed of DNA and hemin-appended poly(ethyleneimine) (H-PEI) were prepared by a layer-by-layer deposition of DNA and H-PEI through an electrostatic interaction.
Kentaro Yoshida   +4 more
doaj   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Hemin reduces inflammation associated with TNBS-induced colitis

open access: yes, 2018
Vanessa Mateus,1,2 João Rocha,2 Hélder Mota-Filipe,2 Bruno Sepodes,2 Rui Pinto2,3 1H&TRC – Health and Technology Research Center, ESTeSL – Lisbon School of Health Technology, Instituto Politécnico de Lisboa, Lisbon ...
Pinto R   +4 more
core  

One-Step Solvothermal Synthesis of Carbon Dots for Rapid and Accurate Determination of Hemin Content

open access: yesMolecules
The development of sensitive and specific methods for the high-quality analysis of hemin-related drugs is significant in the pharmaceutical field. In this work, a simple and rapid method based on the fluorescent properties of carbon dots (CDs) was ...
Yiaobo Zhang   +5 more
doaj   +1 more source

Cost savings with hemin versus givosiran for the treatment of patients with acute intermittent porphyria (AIP)

open access: yesJournal of Medical Economics, 2020
Objective Since 1983, hemin has been FDA-approved for acute intermittent porphyria (AIP) attacks. In 2019, FDA approved givosiran for the treatment of adults with acute hepatic porphyria.
S. Massachi   +3 more
semanticscholar   +1 more source

A Novel Plasma Heme Assay Reveals Disease Severity in Beta‐Thalassemia and Sickle Cell Anemia

open access: yesAmerican Journal of Hematology, Volume 101, Issue 7, Page 1706-1716, July 2026.
ABSTRACT Anemia results from imbalanced hemoglobin or red blood cell production and clearance. Hemolytic anemia, caused by premature red blood cell removal, can be intravascular (in blood) or extravascular (erythrophagocytosis). Hemolysis is common in Sickle Cell Disease (SCD) and Beta‐Thalassemia anemia (β‐thalassemia), the most prevalent inherited ...
Laurent Kiger   +14 more
wiley   +1 more source

The Comparison of Acetic Acid and Strontium Chloride Procedures for Extraction of Hemin

open access: yesMedical Laboratory Journal, 2007
Background and objectives: Hemin is a porphyrin compound derived from hemoglobin, the precursor of other porphyrin hemoglobin derivatives and the raw material of Hematin.
A Alavi   +4 more
doaj  

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