Results 81 to 90 of about 39,725 (289)

Proteomic analysis of the effect of hemin in breast cancer

open access: yesScientific Reports, 2023
Heme, an iron-containing prosthetic group found in many proteins, carries out diverse biological functions such as electron transfer, oxygen storage and enzymatic reactions.
G. P. Coló   +8 more
doaj   +1 more source

Supramolecular Assembly of Stepped‐Persistent ROS Nanogenerator for Sustained Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
ROS catalytic systems often fail to achieve both effective tumor elimination and persistent immune activation due to their monotonous ROS production profiles. A stepped‐persistent ROS nanogenerator was developed by supramolecularly assembling multiple ROS generation modules within a nanofiber structure to simultaneously extend ROS generation duration ...
Zhenqiang Wang   +10 more
wiley   +1 more source

Selective oxidation of ethylbenzene by a biomimetic combination: Hemin and N-hydroxyphthalimide (NHPI)

open access: yes, 2007
A biomimetic catalytic system consisting of hemin and N-hydroxyphthalimide (NHPI) for the selective oxidation of ethylbenzene with dioxygen is reported. 90.32% conversion of ethylbenzene with 94.30% selectivity for acetophenone (AcPO) can be obtained at ...
Xu, Jie   +5 more
core   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

open access: yesBMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma   +9 more
wiley   +1 more source

Hemin-binding ability of LipL41.

open access: yes, 2013
(A) The hemin binding of LipL41 was examined by hemin-agarose beads. Shown are input sample (Input), hemin-agarose-bound (Bound) and resulting flow through (FT), and the non-specific binding control of agarose-bound (Bound) and resulting flow through (FT)
Yuh-Ju Sun (151128)   +7 more
core   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

open access: yesBMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong   +11 more
wiley   +1 more source

Insights into G-Quadruplex–Hemin Dynamics Using Atomistic Simulations: Implications for Reactivity and Folding

open access: yesbioRxiv, 2020
Guanine quadruplex nucleic acids (G4s) are involved in key biological processes such as replication or transcription. Beyond their biological relevance, G4s find applications as biotechnological tools since they readily bind hemin and enhance its ...
Petr Stadlbauer   +7 more
semanticscholar   +1 more source

Microbial keystone taxa and metabolic signatures in centenarians regulate intestinal homeostasis during aging

open access: yesiMeta, EarlyView.
Clostridium scindens and its metabolite indole‐3‐acetic acid (IAA) are identified as a keystone taxon and metabolic signature in centenarians. Clostridium scindens enhances microbial network stability and produces IAA via its own amidase (AMIE) and aldehyde dehydrogenase (ALDH), thus promoting intestinal homeostasis by activating the aryl hydrocarbon ...
Wei‐Chuan Lin   +13 more
wiley   +1 more source

Polymeric Membrane Neutral Phenol-Sensitive Electrodes for Potentiometric G-Quadruplex/Hemin DNAzyme-Based Biosensing

open access: yes, 2013
The first potentiometric transducer for G-quadruplex/hemin DNAzyme-based biosensing has been developed by using potential responses of electrically neutral oligomeric phenols on polymeric membrane electrodes. In the presence of G-quadruplex/hemin DNAzyme
Ren, Qingwei   +3 more
core   +1 more source

Tiny carriers, big impact: How Fusobacterium nucleatum extracellular vesicles drive oral diseases and beyond

open access: yesInterdisciplinary Medicine, EarlyView.
This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma   +6 more
wiley   +1 more source

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