Results 181 to 190 of about 34,452 (261)

G-Quadruplex/Hemin DNAzyme-Functionalized Silver Nanoclusters with Synergistic Antibacterial and Wound Healing Capabilities for Infected Wound Management.

Small, 2023
Systematic management of infected wounds requires simultaneous antiinfection and wound healing, which has become the current treatment dilemma. Recently, a multifunctional silver nanoclusters (AgNCs)-based hydrogel dressing to meet these demands is ...
Jiaojiao Zhu, Tiao Wen, Shuangquan Qu, Qingnian Li, Biwu Liu, Wenhu Zhou   +5 more
semanticscholar   +1 more source

Colorimetric and Photocurrent-Polarity-Switching Photoelectrochemical Dual-Mode Sensing Platform for Highly Selective Detection of Mercury Ions Based on the Split G-Quadruplex-Hemin Complex.

Analytical Chemistry, 2022
Mercury ion (Hg2+) is one of the most harmful heavy metal ions with the greatest impact on public health. Herein, based on the excellent catalytic activity toward 3,3',5,5'-tetramethylbenzidine (TMB) and the strong photocurrent-polarity-switching ability
Yamin Fu, Cuicui Du, Qingqing Zhang, Ke Xiao, Xiaohua Zhang, Jinhua Chen   +5 more
semanticscholar   +1 more source

Enzyme-Loaded Hemin/G-Quadruplex-Modified ZIF-90 Metal-Organic Framework Nanoparticles: Bioreactor Nanozymes for the Cascaded Oxidation of N-hydroxy-l-arginine and Sensing Applications.

Small, 2022
Biocatalytic cascades are challenging to operate in homogeneous solution, where diffusional mass transport hinders efficient communication between the reactive components.
C. Chen, M. Vázquez‐González, Michael P. O’Hagan, Yuanyuan Ouyang, Zhanhui Wang, I. Willner   +5 more
semanticscholar   +1 more source

Highly Sensitive Biosensing Applications of a Magnetically Immobilizable Covalent G-Quadruplex-Hemin DNAzyme Catalytic System.

Analytical Chemistry, 2022
G-quadruplex/hemin (G4/hemin) DNAzymes are biosensing systems, but their application remains limited by an overall low activity and a rather high level of unwarranted background reactions.
Yun Chen, Dehui Qiu, Xiaobo Zhang, Yuan Liu, Mingpan Cheng, Jianping Lei, J. Mergny, H. Ju, Jun Zhou   +8 more
semanticscholar   +1 more source

Hemin mitigates contrast‐induced nephropathy by inhibiting ferroptosis via HO‐1/Nrf2/GPX4 pathway

Clinical and Experimental Pharmacology and Physiology, 2022
Contrast‐induced nephropathy (CIN) is a common complication with adverse outcome after iodinated‐contrast injection, yet still lacking effective medication. Heme oxygenase‐1 (HO‐1) has been reported to play an important role against renal injuries. Hemin,
Zhao Gao, Ziyue Zhang, Daqian Gu, Yunqian Li, Kun Zhang, Xiaoli Dong, Lingli Liu, Jiye Zhang, Jimin Chen, Duozhi Wu, M. Zeng   +10 more
semanticscholar   +1 more source

Generation of high-valent iron-oxo porphyrin cation radicals on hemin loaded carbon nanotubes for efficient degradation of sulfathiazole.

Journal of Hazardous Materials, 2022
Hemin has attracted considerable interest as an efficient catalyst recently, however, its direct application is inefficient due to severe molecular aggregation. Immobilizing hemin on various supports is a feasible approach to address this issue.
Sijing Chen, Zhen Li, Longsheng Wu, Lu Liu, Jingping Hu, Huijie Hou, S. Liang, Jiakuan Yang   +7 more
semanticscholar   +1 more source

Biomimetic design of graphdiyne supported hemin for enhanced peroxidase-like activity.

Journal of Colloid and Interface Science, 2021
Effective electronic interactions between molecular catalysts and supports are critical for heterogeneous enzyme mimics, yet they are frequently neglected in most catalyst designs.
Tao Wang, Xuelong Bi, Lina Wang, Manhong Liu, William W. Yu, Zhiling Zhu, Ning Sui   +6 more
semanticscholar   +1 more source

Highly-sensitive and fast detection of human telomeric G-Quadruplex DNA based on a hemin-conjugated fluorescent metal-organic framework platform.

Biosensors & bioelectronics, 2021
The formation of G-quadruplex (G4) structures in Human telomeric DNA (H-Telo) has been demonstrated to inhibit the activity of telomerase enzyme that is associated with the proliferation of many cancer cells.
Vahid Javan Kouzegaran, K. Farhadi, Mehrdad Forough, M. Bahram, Özgül Persil Çetinkol   +4 more
semanticscholar   +1 more source

Hemin enhances radiosensitivity of lung cancer cells through ferroptosis.

Experimental Cell Research, 2021
The principle underlying radiotherapy is to kill cancer cells while minimizing the harmful effects on non-cancer cells, which has still remained as a major challenge.
W. A. Almahi, K. N. Yu, F. Mohammed, Peizhong Kong, W. Han   +4 more
semanticscholar   +1 more source

Enhancing Microcirculation on Multitriggering Manner Facilitates Angiogenesis and Collagen Deposition on Wound Healing by Photoreleased NO from Hemin-Derivatized Colloids

ACS Nano, 2019
A deficiency of nitric oxide (NO) supply has been found to impair wound healing. The exogenous topical delivery of NO is a promising approach to enhance vasodilation and stimulate angiogenesis and collagen deposition.
Chia-Hao Su, Wei-Peng Li, Chen-Sheng Yeh
exaly   +2 more sources