Probing the Substrate Promiscuity of Isopentenyl Phosphate Kinase as a Platform for Hemiterpene Analogue Production [PDF]
ChemBioChem, 2019 Abstract Isoprenoids are a large class of natural products with wide‐ranging applications. Synthetic biology approaches to the manufacture of isoprenoids and their new‐to‐nature derivatives are limited due to the provision in nature of just two hemiterpene building blocks for isoprenoid biosynthesis.
Sean Lund +2 more
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GeroScience, 2020 Terpenes and their derivatives have been used conventionally as potential dietary supplements to boost the nutritional value of endless food products. Several plant-based complex terpenoid and their derivatives have been reported for a wide range of medicinal and nutritional properties. However, their simple counterparts, whose production is relatively
Suresh Chandra Phulara +5 more
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Plant-Origin Coumarin-Hemiterpene Ethers and Their Chemotaxonomic Significance [PDF]
Jundishapur Journal of Natural Pharmaceutical ProductsContext: A particular class of coumarins, known as coumarin-hemiterpene ethers (CHEs), consists of a coumarin nucleus and a prenyloxy portion. No detailed report on natural coumarin-hemiterpene ethers (NCHEs) and their plant sources is available.
Saba Rahimi Bahoosh, Mahdi Mojarrab
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Synthetic Biology and Metabolic Engineering of Microalgae for Sustainable Lipid and Terpenoid Production: An Updated Perspective. [PDF]
Plant Biotechnol JABSTRACT Microalgae are increasingly recognised as powerful platforms for the sustainable production of lipids and terpenoids, with expanding applications in the food, fuel and biomanufacturing industries. In this updated review, we consolidate and critically assess the most recent advances in synthetic biology and metabolic engineering of key ...
Shitanaka T +6 more
europepmc +2 more sources
New Bitter-Tasting Hemiterpene Glycosides from the Japanese Fern Hymenophyllum barbatum.
Chemical and Pharmaceutical Bulletin, 2001 Hymenosides G--J were newly isolated from the Japanese fern Hymenophyllum barbatum, in addition to hymenosides A--F. The structures of hymenosides were elucidated by extensive two-dimensional nuclear magnetic resonance and/or chemical evidence. The structures of those aglycones were divided into three types, 1,4-dihydroxy-2-hydroxymethyl-but-2-ene, 1,4-
Masao Toyota +2 more
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Biochemical Characterization and Homology Modeling of Methylbutenol Synthase and Implications for Understanding Hemiterpene Synthase Evolution in Plants [PDF]
Journal of Biological Chemistry, 2011 2-Methyl-3-buten-2-ol (MBO) is a five-carbon alcohol produced and emitted in large quantities by many species of pine native to western North America. MBO is structurally and biosynthetically related to isoprene and can have an important impact on regional atmospheric chemistry.
Dennis W. Gray +3 more
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Hymenosides A-F, Six New Hemiterpene Glucosides from the Japanese Fern Hymenophyllum barbatum.
Chemical and Pharmaceutical Bulletin, 2001 In the course of investigation of the bitter-tasting substances of the Japanese fern Hymenophyllum barbatum belonging to the family Hymenophyllaceae, six new hemiterpene glucosides called hymenosides A-F (1-6) have been isolated from the methanol extract, together with an acyclic bis-bibenzyl derivative, perrottetin H.
Yasushi Oiso +2 more
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Cover Feature: Probing the Substrate Promiscuity of Isopentenyl Phosphate Kinase as a Platform for Hemiterpene Analogue Production (ChemBioChem 17/2019) [PDF]
ChemBioChem, 2019 Sean Lund +2 more
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Could the Biological Potency of Porcelia macrocarpa R.E. Fries (Annonaceae) be Linked to Its Diverse Metabolite Profile? [PDF]
Chem BiodiversABSTRACT Porcelia macrocarpa is a Brazilian plant species belonging to the Annonaceae family. To date, more than 190 compounds have been identified and/or isolated from this species, with terpenoids comprising the majority (62%). Alkaloids represent the second most abundant class (11%), followed by steroids (4%), acetogenins (4%), fatty acids (4 ...
Thevenard F +4 more
europepmc +2 more sources
New Coumarin-Hemiterpene Ether Glucosides and a Structurally Related Phenylpropanoic Acid Derivative from Artemisia Armeniaca [PDF]
Natural Product Communications, 2010 Two new coumarin-hemiterpene ether glucosides, 4’- O-(β-D-glucopyranosyl) desoxylacarol (1), and 5- O-(β-D-glucopyranosyl) lacarol (2), were isolated from the methanolic extract of the aerial parts of Artemisia armeniaca Lam. Their structures were established by means of spectroscopic analysis including 1H- and 2D-NMR, HRESIMS, and acid hydrolysis. In
Mahdi Mojarrab +3 more
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