Drug Removal by Hemoadsorption
Blood PurificationBackground: There is growing interest in hemoadsorption (HA) therapies in critically ill patients although their precise indications remain to be established. Several devices are available on the market with heterogeneous properties and capabilities. Summary: Due to the nonspecific removal associated with most HA techniques, concerns have been raised ...
Ilona Lemagnen +6 more
openaire +4 more sources
Removal of Ticagrelor by Hemoadsorption with the HA380 Cartridge
Blood PurificationIntroduction: Hemoadsorption has emerged as a potential intervention for the removal of ticagrelor. We aimed to evaluate the efficacy of the HA380 hemoadsorption cartridge for this purpose. Methods: Six healthy adult sheep received 270 mg of ticagrelor via an orogastric tube, followed by hemoadsorption using a HA380 cartridge for a duration of 4 h. The
Taku Furukawa +9 more
openaire +4 more sources
The Effect of Hemoadsorption with CytoSorb on Severe COVID-19 Complications
Общая реаниматологияThe aim of the study was to assess the effect of hemoadsorption with CytoSorb on the inflammatory response, respiratory failure, and mortality in patients with severe novel coronavirus infection.Materials and methods.
A. S. Rybalko +7 more
doaj +2 more sources
Hemoadsorption corrects hyperresistinemia and restores anti-bacterial neutrophil function
Intensive Care Medicine Experimental, 2017 Background Mounting evidence suggests that sepsis-induced morbidity and mortality are due to both immune activation and immunosuppression. Resistin is an inflammatory cytokine and uremic toxin.
Anthony Bonavia +3 more
doaj +2 more sources
Hemoadsorption by CytoSorb in septic patients: a case series [PDF]
Critical Care, 2017 Septic shock, defined as life-threatening organ dysfunction caused by a dysregulated host response to infection, is a highly lethal condition that causes substantial morbidity and mortality among critically ill patients. One of the hallmarks of sepsis is the excessive release of cytokines and other inflammatory mediators causing refractory hypotension,
Klaus Kogelmann +3 more
openaire +5 more sources
Extracorporeal Cytokine Hemadsorption for the Treatment of Severe Steroid Refractory Cytokine Release Syndrome Secondary to T-Cell Immunotherapy for B-Cell Malignancies: A Case Series. [PDF]
Hematol OncolHematological Oncology, Volume 44, Issue 4, July 2026.
Cavallaro G +12 more
europepmc +2 more sources
Case Report: Adjunctive hemoadsorption therapy in a patient with Takotsubo cardiomyopathy and hyperinflammation [PDF]
Frontiers in MedicineIntroductionTakotsubo cardiomyopathy (TCM) is a transient, stress-related cardiac dysfunction that mimics acute coronary syndrome and is typically seen in postmenopausal women.
Jose O. Castro
doaj +2 more sources
Efficacy of hemoadsorption in the severe course of COVID-19
Frontiers in MedicineIntroductionInsufficiencies of the majority of targeted therapies for the most severe, life-threatening forms of COVID-19 warrant alternative, adjuvant treatment options for enhanced life maintenance that include extracorporeal blood purification and ...
Aleksei Yurievitch Yakovlev +7 more
doaj +3 more sources
Evaluation of Hemoadsorption Capacity of the CytoSorb Adsorber for Toxic Doses of Diclofenac and Meloxicam in Porcine Plasma. [PDF]
J Clin ApherABSTRACT The objective of this in vitro experimental was to determine the utility of hemoadsorption (HA) using the CytoSorb adsorber to remove meloxicam and diclofenac from porcine plasma. For this purpose 12 1‐L aliquots of porcine plasma, 6 units were spiked with 293 μg/mL (262–320 μg/mL) diclofenac and 6 with 42.8 μg/mL (41.4–44.7 μg/mL) meloxicam ...
Giani B +3 more
europepmc +2 more sources