Results 21 to 30 of about 1,565 (185)

Timing of hemoadsorption in sepsis: redefining early through mediator-guided therapy [PDF]

Journal of Intensive Care
Background Hemoadsorption is gaining acceptance as an adjunctive extracorporeal blood purification strategy in sepsis and septic shock; however, its clinical value remains contingent on two closely linked variables: when therapy is initiated and in whom ...
Prit Kusirisin, John A. Kellum, Nattachai Srisawat   +2 more
doaj   +2 more sources

Bacterial Superantigen-Mediated Toxic Shock: Hyperinflammatory Trajectories and Extracorporeal Immunomodulation in Streptococcal Toxic Shock Syndrome [PDF]

Toxins
Streptococcal toxic shock syndrome (STSS) is a fulminant manifestation of invasive group A Streptococcus infection characterized by superantigen-driven hyperinflammation, refractory shock, and rapidly progressive multiorgan dysfunction.
Kuo-Hao Lo, Kuo-Cheng Lu, Yen-Hung Liu, Yi-Chou Hou   +3 more
doaj   +2 more sources

CytoSorb^® Hemoadsorption in Post-Cardiac Arrest Syndrome After Out-of-Hospital Cardiac Arrest: A Propensity Score-Matched Cohort Study [PDF]

Biomedicines
Background: Post-cardiac arrest syndrome (PCAS) following out-of-hospital cardiac arrest (OHCA) is driven by global ischemia–reperfusion injury, endothelial dysfunction, and a dysregulated inflammatory response.
Julian Kreutz, Klevis Mihali, Vivien Sievertsen, Lukas Harbaum, Georgios Chatzis, Styliani Syntila, Bernhard Schieffer, Birgit Markus   +7 more
doaj   +2 more sources

Early use of hemoadsorption in patients after out-of hospital cardiac arrest - a matched pair analysis. [PDF]

PLoS ONE, 2020
BackgroundPro- and anti-inflammatory mediators are released during and after cardiac arrest, which may be unfavourable. Small case-series and observational studies suggested that unselective hemoadsorption may reduce inadequately high cytokine levels ...
Muharrem Akin, Vera Garcheva, Jan-Thorben Sieweke, Ulrike Flierl, Hannah C Daum, Johann Bauersachs, Andreas Schäfer   +6 more
doaj   +2 more sources

Severe Diltiazem Poisoning Managed With CytoSorb Hemoadsorption and Supportive Therapies: A Case Report [PDF]

Critical Care Explorations
BACKGROUND:. Severe intoxication with nondihydropyridine calcium channel blockers, such as diltiazem, is associated with high morbidity and mortality. Evidence supporting extracorporeal treatment strategies remains limited.
Juul M. Cox, PharmD, Julia A. M. Verwaaijen, MD, Ruben M. F. Hendriks, BSc, Dorien Smeets, PharmD, Suzanne van Rijswijk, MD, Tessa M. Bosch, PharmD, PhD   +5 more
doaj   +2 more sources

Effects of hemoadsorption on plasma catecholamine levels: an in vitro study [PDF]

Scientific Reports
Hemoadsorption with polystyrene-divinylbenzene (PS-DVB)-based adsorbents is explored as an adjunctive extracorporeal therapy in selected critically ill patients with dysregulated systemic inflammation.
Andreas Körtge, Gerd Klinkmann, Christoph Kamper, Reinhold Wasserkort, Steffen Mitzner   +4 more
doaj   +2 more sources

The effects of hemoadsorption in patients with sepsis-associated persistent severe AKI who require CRRT: A prospective, randomized controlled pilot study [PDF]

Annals of Intensive Care
Background: Sepsis-associated persistent severe acute kidney injury (S-PAKI) is marked by a sustained hyperinflammatory response and is associated with a poor prognosis.
Keran Shi, Wei Jiang, Lin Song, Yuchen Wang, Xianghui Li, Jing Wang, Ying Shi, Zhixiang Yang, Xing Cai, Wei Han, Jiujiang Liu, Jingjing Yin, Xiaohua Gu, Qingquan Lyu, Xiaolan Xu, Renyan Zhao, Haixia Wang, Qiaoping Chen, Qingjie Zhu, Xiaoyan Wu, Jiangquan Yu, Ruiqiang Zheng   +21 more
doaj   +2 more sources

The Immunomodulatory Potential of Hemoadsorption in Burn Care

Blood Purification
Background: Burns are a common injury affecting thousands of people worldwide each year. Clinical severity varies according to the total body surface area burned, which is in turn associated with morbidity and mortality. The management of a severe burn patient requires admission to a referral center.
Nicolas Chardon, Frank Bidar, Paul Samuel Abraham, Céline Monard, Kevin K. Chung, Thomas Rimmelé   +5 more
openaire   +4 more sources

Post VV-ECMO Weaning Hyperinflammation—Can Prophylactic Hemoadsorption Treatment Prevent Complications?

Medicina, 2023
Acute respiratory distress syndrome (ARDS) is a severe clinical condition characterized by acute respiratory failure and a high mortality risk despite conventional mechanical ventilatory support.
Pedja Kovacevic, Sasa Dragic, Milka Jandric, Danica Momcicevic, Sandra Topolovac, Vedrana Malesevic, Tijana Kovacevic, Marijana Matejic-Spasic, Tanja Knezevic, Biljana Zlojutro   +9 more
doaj   +2 more sources

The use of CytoSorb hemoadsorption in critically ill patients: a narrative review [PDF]

Frontiers in Medicine
Inflammation, a complex biological response against injury or infection, is an important pathological basis for various critical diseases. A “normal” immune response exemplifies a balanced dialogue between immunological cells and a medley of pro- and ...
Kaixin Lei, Ao Chen, Xinqi An, Jun Guo, Baihai Su, Baihai Su, Baihai Su, Yupei Li   +7 more
doaj   +2 more sources