Results 1 to 10 of about 21,101 (162)
Successful IVIG Treatment in Neonatal Hemochromatosis Without Extrahepatic Siderosis: A Case Report [PDF]
ReportsBackground and Clinical Significance: Neonatal hemochromatosis is a rare iron overload disorder that causes severe liver injury in newborns, typically with extrahepatic siderosis.
Gwan Yong Lim +4 more
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Case Report: Secukinumab for the treatment of severe psoriasis in a patient with hereditary hemochromatosis [PDF]
Frontiers in MedicineThere are several comorbidities associated with psoriasis, including genetic disorders such as hereditary hemochromatosis, which can lead to organ damage secondary to iron overload.
Yingzhe Yu +4 more
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An unusual dyspnea in an 87-year old woman affected by Sjögren’s syndrome [PDF]
Beyond Rheumatology, 2021 Primary Sjögren’s syndrome (pSS) is a progressive autoimmune disease and is characterized by eye and mouth dryness due to lymphocytic infiltration in lacrimal and salivary glands leading to tissue destruction, but it can also present systemic ...
Carlo Grendene +4 more
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Iron in Porphyrias: Friend or Foe?
Diagnostics, 2022 Iron is a trace element that is important for many vital processes, including oxygen transport, oxidative metabolism, cellular proliferation, and catalytic reactions. Iron supports these functions mainly as part of the heme molecule. Heme synthesis is an
Elena Buzzetti +2 more
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HFE hemochromatosis: an overview about therapeutic recommendations
Hematology, Transfusion and Cell Therapy, 2022 Hemochromatosis is currently characterized by the iron overload caused by hepcidin deficiency. Large advances in the knowledge on the hemochromatosis pathophysiology have occurred due to a better understanding of the protein of the iron metabolism, the ...
Rodolfo D. Cancado +2 more
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Acta Marisiensis - Seria Medica, 2022 Objective: Hereditary hemochromatosis, or primary hemochromatosis, is a recessive genetic liver disorder caused by iron accumulation in tissues. This study evaluates patients with hereditary hemochromatosis to determine correlations between clinical and ...
Sigmirean Victor
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Juvenile Hemochromatosis due to a Homozygous Variant in the HJV Gene
Case Reports in Pediatrics, 2022 Hemochromatosis type 2 or juvenile hemochromatosis has an early onset of severe iron overload resulting in organ manifestation such as liver fibrosis, cirrhosis, cardiomyopathy, arthropathy, hypogonadism, diabetes, osteopathic medicine, and thyroid ...
María-Belén Moreno-Risco +5 more
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Iron Metabolism in the Disorders of Heme Biosynthesis
Metabolites, 2022 Given its remarkable property to easily switch between different oxidative states, iron is essential in countless cellular functions which involve redox reactions. At the same time, uncontrolled interactions between iron and its surrounding milieu may be
Andrea Ricci +5 more
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IRON METABOLISM IN THALASSEMIA AND SICKLE CELL DISEASE
Mediterranean Journal of Hematology and Infectious Diseases, 2009 There are two main mechanisms by which iron overload develops in thalassemias: increased iron absorption due to ineffective erythropoiesis and blood transfusions.
Raffaella Mariani +3 more
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