Results 151 to 160 of about 49,325 (314)
THE NATURE OF STORAGE IRON IN IDIOPATHIC HEMOCHROMATOSIS AND IN HEMOSIDEROSIS [PDF]
G Richter
openalex +1 more source
ABSTRACT The iron regulatory hormone hepcidin contributes to the pathogenesis of anemia of inflammation (AI) by inhibiting the iron exporter ferroportin in target cells, causing hypoferremia. Under acute inflammation, hepcidin induction requires hemojuvelin (Hjv), a bone morphogenetic protein co‐receptor, while Fpn mRNA is also suppressed in a hepcidin‐
Siqi Liu+3 more
wiley +1 more source
Persistent AST Elevation in a Patient With Ovarian Cancer: A Rare Diagnostic Challenge
ABSTRACT Background Persistent elevation of aspartate aminotransferase (AST) is commonly indicative of liver injury or disease, but isolated AST elevation without concurrent alanine aminotransferase (ALT) increase is rare and difficult to diagnose. While AST is non‐specific and found in various tissues, its isolated elevation is due to less common ...
Lechuang Chen, Yu Zhang, Qing H. Meng
wiley +1 more source
The common heritage of mankind : from the law of the sea to the human genome and cyberspace [PDF]
Since Arvid Pardo addressed the UN General Assembly in 1967 and proposed to declare the deep seabed and ocean floor the common heritage of mankind, the need has been felt to adapt the concept of common heritage to the human genome and the internet ...
Buttigieg, Jean
core
Amy G. Feldman, P. Whitington
semanticscholar +1 more source
Hemochromatosis is an inherited iron overload condition caused by mutations that reduce the levels of the iron‐regulatory hormone hepcidin or its binding to ferroportin.
Naja Nyffenegger+7 more
doaj +1 more source
The pathophysiology, presentation and classification of Type 1 diabetes
Abstract Type 1 diabetes is characterised by the autoimmune destruction of pancreatic β‐cells, leading to an absolute or near‐absolute insulin deficiency. Although traditionally associated with childhood onset, it can manifest at any age, and it is increasingly recognised that there is significant heterogeneity in its clinical presentation. This review
Kristie I. Aamodt, Alvin C. Powers
wiley +1 more source
Model of reticuloendothelial iron metabolism in humans: abnormal behavior in idiopathic hemochromatosis and in inflammation [PDF]
Georges Fillet, Y Beguin, L Baldelli
openalex +1 more source
HLA and hemochromatosis disease association in São Miguel Island [PDF]
Mestrado em Biologia Molecular e CelularA hemocromatose hereditária uma doença autossómica recessiva do metabolismo do ferro, geralmente associada à mutação C282Y no gene HFE. Presume-se que a origem desta mutação tenha ocorrido por acaso no haplótipo
Gomes, Cidália Maria Teixeira
core +1 more source
Our study provides genetic analysis supporting the beneficial effects of GLP1 action on MASLD. These benefits may be attributed to mechanisms such as lowering blood glucose levels, reducing blood pressure, and improving HDL cholesterol levels. ABSTRACT Purpose Previous studies have shown that glucagon‐like peptide 1 (GLP1) receptor agonists may help ...
Zhiqiang Ma+3 more
wiley +1 more source