Results 41 to 50 of about 37,295 (215)

Mechanism for Multiple Ligand Recognition by the Human Transferrin Receptor [PDF]

open access: yes, 2003
Transferrin receptor 1 (TfR) plays a critical role in cellular iron import for most higher organisms. Cell surface TfR binds to circulating iron-loaded transferrin (Fe-Tf) and transports it to acidic endosomes, where low pH promotes iron to dissociate ...
Björkman, Pamela J   +3 more
core   +5 more sources

Prevalence of iron deficiency in 62,685 women of seven race/ethnicity groups: The HEIRS Study. [PDF]

open access: yes, 2020
BackgroundFew cross-sectional studies report iron deficiency (ID) prevalence in women of different race/ethnicity and ages in US or Canada.Materials and methodsWe evaluated screening observations on women who participated between 2001-2003 in a cross ...
Acton, Ronald T   +10 more
core  

Dangerous dietary supplements: Garcinia cambogia-associated hepatic failure requiring transplantation. [PDF]

open access: yes, 2016
Commercial dietary supplements are marketed as a panacea for the morbidly obese seeking sustainable weight-loss. Unfortunately, many claims cited by supplements are unsupported and inadequately regulated.
Bodzin, Adam S   +4 more
core   +1 more source

Chronic hepatitis B complicated with secondary hemochromatosis was cured clinically: A case report

open access: yesOpen Medicine, 2023
Chronic hepatitis B (CHB) often causes iron overload in the liver but rarely causes severe secondary hemochromatosis (SH). A 48-year-old man was infected with CHB via vertical transmission. For 21 years, nonstandard treatment with second-line hepatitis B
Ye Yun   +4 more
doaj   +1 more source

Hemojuvelin-Neogenin Interaction Is Required for Bone Morphogenic Protein-4-induced Hepcidin Expression [PDF]

open access: yes, 2009
Hemojuvelin (HJV) is a glycosylphosphatidylinositol-linked protein and binds both bone morphogenic proteins (BMPs) and neogenin. Cellular HJV acts as a BMP co-receptor to enhance the transcription of hepcidin, a key iron regulatory hormone secreted ...
An-Sheng Zhang   +44 more
core   +3 more sources

Hereditary hemochromatosis associated with autoimmune hemolytic anemia; A case report [PDF]

open access: yesJournal of Preventive Epidemiology, 2019
Hereditary hemochromatosis is a disease associated with highly iron overload. This disease caused by genetic mutations inherited through family. Autoimmune hemolytic anemia is also an important autoimmune disease in which red blood cells (RBC) are ...
Masih Falahatian   +2 more
doaj  

Liver transplantation for alcoholic cirrhosis: Long term follow-up and impact of disease recurrence [PDF]

open access: yes, 2001
Background. Alcoholic liver disease has emerged as a leading indication for hepatic transplantation, although it is a controversial use of resources. We aimed to examine all aspects of liver transplantation associated with alcohol abuse.
Andrea M. DiMartini   +71 more
core   +1 more source

In-silico Molecular Analysis of Mutated Sequences of HFE1, HFE2, TFR2 and SLC40A1 causing Hemochromatosis Disease [PDF]

open access: yesInternational Journal Bioautomation, 2011
Hemochromatosis is a disorder in iron metabolism that is characterized by excess iron absorption. There are two forms of hemochromatosis: primary hemochromatosis is caused by a problem with your genes.
Bilal Hussain   +4 more
doaj  

A Late Presentation of a Fatal Disease: Juvenile Hemochromatosis

open access: yesCase Reports in Medicine, 2013
Juvenile hemochromatosis is a rare and severe form of hereditary hemochromatosis. We report the case of a 39-year-old female who presented with heart failure and cirrhosis from previously unrecognized juvenile hemochromatosis.
Cynthia Cherfane   +3 more
doaj   +1 more source

Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells [PDF]

open access: yes, 2005
Type 2 hereditary hemochromatosis (HH) or juvenile hemochromatosis is an early onset, genetically heterogeneous, autosomal recessive disorder of iron overload.
Bjorkman, Pamela J.   +4 more
core   +1 more source

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