Results 41 to 50 of about 47,935 (263)
Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous genotype
Hepatology International, 2018 Although guidelines are available for hereditary hemochromatosis, a high percentage of the recommendations within them are not shared between the different guidelines.
P. Adams +28 more
semanticscholar +1 more source
Complete heart block with ventricular tachycardia in a patient with hemochromatosis
Saudi Journal of Medicine and Medical Sciences, 2014 Hereditary hemochromatosis is an inherited condition of dysregulated iron absorption, and usually presents with clinical features of hepatic dysfunction. Cardiac involvement as the presenting manifestation of hereditary hemochromatosis is rare. We report
Sajeer Kalathingathodika +3 more
doaj +1 more source
Hepcidin and Host Defense against Infectious Diseases. [PDF]
, 2015 Hepcidin is the master regulator of iron homeostasis in vertebrates. The synthesis of hepcidin is induced by systemic iron levels and by inflammatory stimuli.
Ganz, Tomas +3 more
core +1 more source
The Myths and Realities of Hemochromatosis
Canadian Journal of Gastroenterology, 2007 Hemochromatosis is a common genetic condition and yet there are still a number of misperceptions surrounding the diagnosis and management of this condition. Hemochromatosis affects both men and women.
Melanie D Beaton, Paul C Adams
doaj +1 more source
Iron overload exacerbates age-associated cardiac hypertrophy in a mouse model of hemochromatosis
Scientific Reports, 2017 Cardiac damage associated with iron overload is the most common cause of morbidity and mortality in patients with hereditary hemochromatosis, but the precise mechanisms leading to disease progression are largely unexplored.
Abitha Sukumaran +5 more
semanticscholar +1 more source
Identification of erythroferrone as an erythroid regulator of iron metabolism. [PDF]
, 2014 Recovery from blood loss requires a greatly enhanced supply of iron to support expanded erythropoiesis. After hemorrhage, suppression of the iron-regulatory hormone hepcidin allows increased iron absorption and mobilization from stores.
Ganz, Tomas +5 more
core +1 more source
Immunity, Inflammation and Disease, 2017 Since its discovery, the hemochromatosis protein HFE has been primarily defined by its role in iron metabolism and homeostasis, and its involvement in the genetic disease termed hereditary hemochromatosis (HH).
A. Reuben +3 more
semanticscholar +1 more source
Hereditary hemochromatosis associated with autoimmune hemolytic anemia; A case report [PDF]
Journal of Preventive Epidemiology, 2019 Hereditary hemochromatosis is a disease associated with highly iron overload. This disease caused by genetic mutations inherited through family. Autoimmune hemolytic anemia is also an important autoimmune disease in which red blood cells (RBC) are ...
Masih Falahatian +2 more
doaj
Frontiers in Medicine, 2021 Hereditary hemochromatosis is a genetic iron overload disease related to a mutation within the HFE gene that controls the expression of hepcidin, the master regulator of systemic iron metabolism. The natural stable iron isotope composition in whole blood
Emmanuelle Albalat +5 more
doaj +1 more source
Safety Aspects of Iron in Food [PDF]
, 2001 During the last decades efforts regarding dietary iron supply focused mostly on the prevention of deficiencies, especially during growth and pregnancy.
Schümann, Klaus
core +1 more source