Results 61 to 70 of about 27,519 (222)
The Development of Hemochromatosis after Treatment for Celiac Sprue
Canadian Journal of Gastroenterology, 1994 Celiac sprue is a chronic disease characterized by maldigestion and malabsorption. Whereas many diseases have been reported in association with celiac sprue, hemochromatosis has not.
Mang Ma, Edmond A Ryan, Vincent G Bain
doaj +1 more source
The role of iron in normal and impaired testicular function
Andrology, EarlyView.Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer +2 more
wiley +1 more source
A Rare Presentation of Transfusional Hemochromatosis: Hypogonadotropic Hypogonadism
Case Reports in Endocrinology, 2015 Hemochromatosis is a disease caused by extraordinary iron deposition in parenchymal cells leading to cellular damage and organ dysfunction. β-thalassemia major is one of the causes of secondary hemochromatosis due to regular transfusional treatment for ...
Rifki Ucler +6 more
doaj +1 more source
Rare Variants in PFIC‐Related Genes Among Adults With Intrahepatic Cholestasis
Hepatology Research, EarlyView.ABSTRACT Aim Biallelic pathogenic variants in progressive familial intrahepatic cholestasis (PFIC)‐related genes cause severe pediatric cholestasis. However, the clinical significance of heterozygous variants in adult intrahepatic cholestasis remains unclear.
Shunji Hirose +9 more
wiley +1 more source
Variable expressivity of HJV related hemochromatosis: “Juvenile” hemochromatosis?
, 2019 International audienceJuvenile hemochromatosis is a rare autosomal recessive disease due to variants in the Hemojuvelin (HJV) gene. Although biological features mimic HFE hemochromatosis, clinical presentation is worst with massive iron overload ...
Detivaud, Lenaick +9 more
core +1 more source
Mechanisms of Thrombocytosis in Iron‐Deficiency Anemia
European Journal of Haematology, Volume 117, Issue 4, Page 728-738, October 2026.ABSTRACT Iron‐deficiency anemia is frequently accompanied by reactive thrombocytosis, yet the mechanisms underlying this association remain incompletely understood. Beyond impaired erythropoiesis, iron availability has emerged as an active regulator of hematopoietic lineage decisions.
João Vitor Facco +2 more
wiley +1 more source
, 2011 With the identification of the HFE gene in 1996, the majority of cases of hereditary hemochromatosis (HH) or type 1 HH were found to be associated with homozygosity for a mutation leading to a cysteine to tyrosine substitution (C282Y) in the HFE protein.
Wallace, Daniel F. +3 more
core +1 more source
Journal of Education, Health and SportIntroduction: Hereditary hemochromatosis is the most common genetic disorder in Northern Europe. It involves an overload of iron in the tissues due to a deficiency of the protein hepcidin.
Dominika Prystacka-Szar +9 more
doaj +1 more source
Should the Children of Patients with Hemochromatosis be Screened for the Disease?
Canadian Journal of Gastroenterology, 1988 Idiopathic hemochromatosis is an underdiagnosed treatable condition inherited in an autosomal recessive pattern. Since early treatment is of demonstrated value, screening of high risk groups of individuals in a valuable exercise in preventive medicine ...
Donald G. MacIntosh +5 more
doaj +1 more source
Spontaneous Hepatobiliary Disease in a Breeding Colony of Aotus spp.
Journal of Medical Primatology, Volume 55, Issue 5, October 2026.ABSTRACT Background Owl monkeys are nonhuman primate species in the genus Aotus. The Michale E. Keeling Center for Comparative Medicine and Research maintains an Owl Monkey Breeding and Research Resource composed of four species of owl monkeys: Aotus nancymai, A. vociferans, A. azarae, and A. griseimembra.
M. E. Hensel +4 more
wiley +1 more source