Results 71 to 80 of about 37,115 (234)

Consumer use and response to online third-party raw DNA interpretation services [PDF]

, 2018
This study was funded in part by a pilot grant from the Boston University School of Public Health.
Brett, Cariaso, Carroll, Collins, Darst, Kirkpatrick, Koeller, Mainous, Powell, Powell, Roberts, Roberts, Wouden   +12 more
core   +1 more source

Single‐Breathhold 3D MR Elastography in the Liver, With Simultaneous R2* and PDFF Mapping

Magnetic Resonance in Medicine, EarlyView.
Purpose To develop a sequence for the rapid acquisition of MR elastography (MRE) parameters in 3D, with simultaneous measurement of proton‐density fat fraction (PDFF) and R2* for multiparametric assessment of liver disease. Methods The proposed sequence uses an interleaved motion‐encoding scheme to acquire 3D volumes of all motion encodings and wave ...
Donovan P Tripp, Anne‐Sophie van Schelt, Omar Darwish, Karl P Kunze, Shamsa Al Harthy, Nader S Metwalli, Ahmed M Gharib, Claudia Prieto, René M Botnar, Ralph Sinkus, Radhouene Neji   +10 more
wiley   +1 more source

A Rare Presentation of Transfusional Hemochromatosis: Hypogonadotropic Hypogonadism

Case Reports in Endocrinology, 2015
Hemochromatosis is a disease caused by extraordinary iron deposition in parenchymal cells leading to cellular damage and organ dysfunction. β-thalassemia major is one of the causes of secondary hemochromatosis due to regular transfusional treatment for ...
Rifki Ucler, Erdal Kara, Murat Atmaca, Sehmus Olmez, Murat Alay, Yaren Dirik, Aydin Bora   +6 more
doaj   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Hereditary hemochromatosis: pathogenesis, symptoms, diagnosis and current treatment - literature review

Journal of Education, Health and Sport
Introduction: Hereditary hemochromatosis is the most common genetic disorder in Northern Europe. It involves an overload of iron in the tissues due to a deficiency of the protein hepcidin.
Dominika Prystacka-Szar, Natalia Rulewska, Filip Grabowski, Jakub Siemko, Dagmara Neska , Justyna Stadler-Szajda, Adrianna Czyżnikiewicz, Wenancjusz Stołowski, Magdalena Bujak, Magdalena Waśniowska   +9 more
doaj   +1 more source

Patients and blood donors with hemochromatosis: A survey conducted in Førde Health Trust

Bioingeniøren, 2021
Introduction: To allow eligible persons with hemochromatosis to become blood donors will be advantageous for these individuals and for the blood supply.
Turid Aarhus Braseth, Anne Synnøve Røsvik, Tor Audun Hervig   +2 more
doaj  

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Hepatitis C Virus and Hepatocellular Carcinoma: Pathogenetic Mechanisms and Impact of Direct-Acting Antivirals [PDF]

, 2018
INTRODUCTION: Globally, between 64 and 103 million people are chronically infected with Hepatitis C virus (HCV), with more than 4.6 million people in the United States and is associated with more than 15.000 deaths annually.
Petruzziello, Arnolfo, Pinacchio, Claudia, Scheri, Giuseppe Corano, Schietroma, Ivan, Statzu, Maura, Vullo, Vincenzo   +5 more
core   +1 more source

Developmental Trends in Serum Iron, Transferrin, and Transferrin Saturation From Birth to 12 Months

Acta Paediatrica, EarlyView.
ABSTRACT Aim There is a need for updated reference intervals for iron status biomarkers during infancy. This study aimed to investigate reference interval trends and diurnal variation of iron, transferrin, and transferrin saturation in infants subjected to delayed cord clamping at birth (DCC). Methods Data analysis from population‐based Swedish studies,
Sara Marie Larsson, Lena Hellström‐Westas, Ulrica Askelöf, Cecilia Götherström, Magnus Domellöf, Ola Andersson   +5 more
wiley   +1 more source

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis [PDF]

, 2014
Variation in body iron is associated with or causes diseases, including anaemia and iron overload. Here, we analyse genetic association data on biochemical markers of iron status from 11 European-population studies, with replication in eight additional ...
Anderson, Denise, Benyamin, Beben, Broer, Linda, Esko, Tonu, Franke, Lude, Goegele, Martin, Haeldin, Jonas, Jolley, Jennifer, Kiemeney, Lambertus A., Kutalik, Zoltan, Luan, Jian'an, Meitinger, Thomas, Mihailov, Evelin, Milani, Lili, Peters, Annette, Podmore, Clara, Radhakrishnan, Aparna, Rendon, Augusto, Ried, Janina S., Sambrook, Jennifer, Sanna, Serena, Sweep, Fred C., Tanaka, Toshiko, Thiery, Joachim, Traglia, Michela, van der Meer, Peter, Vermeulen, Sita H., Waldenberger, Melanie, Wang, Fudi, Westra, Harm-Jan, Winkelmann, Juliane   +30 more
core   +4 more sources